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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002574
  • pan locus tag?: SAUPAN006275000
  • symbol: JSNZ_002574
  • pan gene symbol?: —
  • synonym:
  • product: TetR/AcrR family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002574
  • symbol: JSNZ_002574
  • product: TetR/AcrR family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 2579761..2580348
  • length: 588
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGATCATAGATCGACGTATTAGAAAATCACAAGTTGCAATGAGAAATGCATTTATTGAA
    CTTTTACATCAACACCAATTAGAAGAGATTACTGTACAACAAATTGCAGATTTAGCTGAT
    GTTAACCGTAGTACATTTTATACGCATTATTATGATAAATATGATTTGCTTGAAAAATTA
    GAGGACCAGCAGTTGGAGGAAATAAGAGACTTCATTCATGATGAGAAGTTAAATGGAGCA
    GTTAAGTTATCCACGGATAACATACATCAAATTATGACCGTTTTAATAGAAATGGTAGAA
    AAAGACATCGCATTTTATCAATTGATGTTTCGTATGGGTAAAGATTCAAATATCCACGAA
    AAACTTTATGATTTAATTATGTGTCATTTACAACGTTATAAAAATGAAAATGATCAAATT
    AATAGTATACCATTTTCCTATTTCATGAGTTATGTTTCAGGTGCGGGATTGTCTTTGATA
    AGACATTGGGTAGAAGATCCAAACCGTATAGATAAAGTTGACTTAATAATGCATTTTAAT
    ACGATTGTCAATCAAGGGCCAGCAACGATAATTAAAAATATACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    588

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002574
  • symbol: JSNZ_002574
  • description: TetR/AcrR family transcriptional regulator
  • length: 195
  • theoretical pI: 5.78931
  • theoretical MW: 23162.4
  • GRAVY: -0.343077

⊟Function[edit | edit source]

  • TIGRFAM:
    probable dihydroxyacetone kinase regulator (TIGR02366; HMM-score: 42.7)
    and 4 more
    Signal transduction Regulatory functions DNA interactions mycofactocin system transcriptional regulator (TIGR03968; HMM-score: 25.8)
    Signal transduction Regulatory functions DNA interactions transcriptional repressor BetI (TIGR03384; HMM-score: 21.2)
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 15.7)
    pyrimidine utilization regulatory protein R (TIGR03613; HMM-score: 13.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    TetR_C (CL0174) TetR_C_8; Transcriptional regulator C-terminal region (PF14278; HMM-score: 49.5)
    and 6 more
    HTH (CL0123) TetR_N; Bacterial regulatory proteins, tetR family (PF00440; HMM-score: 28.3)
    HTH_Tnp_1_2; Helix-turn-helix of insertion element transposase (PF13022; HMM-score: 17.9)
    no clan defined FtsH_ext; FtsH Extracellular (PF06480; HMM-score: 14.3)
    HTH (CL0123) HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 13.3)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 12.7)
    HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9793
    • Cytoplasmic Membrane Score: 0.0174
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.003
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001792
    • TAT(Tat/SPI): 0.000166
    • LIPO(Sec/SPII): 0.000236
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIIDRRIRKSQVAMRNAFIELLHQHQLEEITVQQIADLADVNRSTFYTHYYDKYDLLEKLEDQQLEEIRDFIHDEKLNGAVKLSTDNIHQIMTVLIEMVEKDIAFYQLMFRMGKDSNIHEKLYDLIMCHLQRYKNENDQINSIPFSYFMSYVSGAGLSLIRHWVEDPNRIDKVDLIMHFNTIVNQGPATIIKNIQ

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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