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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0160 [new locus tag: NWMN_RS00875 ]
  • pan locus tag?: SAUPAN001077000
  • symbol: NWMN_0160
  • pan gene symbol?: hptS
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_0160 [new locus tag: NWMN_RS00875 ]
  • symbol: NWMN_0160
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 202776..204332
  • length: 1557
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGACGGCATACAAACCTTATAGACATCAATTAAGACGATCGTTATTTGCGTCTACTATT
    TTTCCAGTATTTTTAGTCATTATTATTGGACTAGTAAGCTTCTATGCCATCTATATTTGG
    ATTGAGCATCGTACGATTCATCAACATGTTGATGAAAGTCAGTCATCTTTACATCATACT
    GAAAAGCAGATTCAGACATTTATTACACAGCATAATAATTCGTTTCAAGAGCTCGATTTA
    ACAAATCATCATGATGTGACCGCTACAAAACGTGAATTATTAAAATTAATACACCAACAG
    CCCGCAACACTTTATTATGAATTATCTGGACCAAATCAGTTTATAACCAATAATTATGAA
    CATTTAAACACTAAAAATATGTATTTATTTTCAACGCATCAGCTTAAATTCAAAAATAGT
    ACATATATGCTTAAAATTTATATGGCTAACACCCCACGTTTAAGTGAAATTAAGAAAGAT
    AACCGACAATTCGCACTTATCGTTGATCAATATGACAATATTTTATACGCCAACGATGAC
    CGTTTTACTATAGGTGAAAAGTATAGACCACAACAATTCGGATTTATGAATGAATCTGTA
    AAATTAAACCATGCTGACCATCGTCTCATTATTTATAAAGATATACATGAAAACATTGAA
    GATGGTATCACGTTGTTAATTGTTATGGCCGTAGTTCTTGTTTTACTAGTAATATTTGGT
    TTCATTAGCGCAGATAATATGGCTAAACGACAAACAAAAGATATCGAAACGATTATTCAA
    AAAATTTACTATGCCAAAAATCGTCATCTAGGTACATATACGCCTTTAAAAAACAACAGT
    GAACTAGAAGAAATTAATAATTATATTTACGATTTATTTGAATCAAATGAGCAACTGATC
    CATTCTATCGAGCATACAGAACGTCGCTTGCGTGATATTCAGTTAAAGGAAATAGAACGC
    CAATTCCAGCCTCATTTCCTATTCAATACGATGCAAACAATACAATATTTAATTACGTTA
    TCTCCGAAATTAGCACAAACTGTGGTCCAACAATTATCGCAAATGTTACGTTACTCATTA
    CGTACAAACTCACATACAGTGGAATTAAACGAAGAGTTGAACTACATTGAACAGTATGTT
    GCAATACAAAACATCCGTTTTGATGACATGATTAAGCTCCATATTGAAAGTTCTGAAGAA
    GCGCGTCACCAGACAATTGGTAAAATGATGCTTCAGCCACTCATAGAAAATGCTATTAAA
    CATGGTAGAGATACTGAGTCATTGGACATTACTATACGCCTGACATTGGCACGTCAGAAT
    TTACATGTTTTAGTTTGCGACAATGGTATCGGGATGTCGTCATCTCGCCTGCAATATGTA
    CGCCAATCTCTTAATAATGATGTATTTGATACTAAGCATTTGGGATTAAATCATTTACAC
    AATAAAGCAATGATTCAATATGGTTCACATGCACGACTCCATATTTTTTCAAAGCGTAAT
    CAAGGTACGTTAATTTGTTATAAAATACCACTTTCAAGGGGGAATGTAGATGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1557

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_0160 [new locus tag: NWMN_RS00875 ]
  • symbol: NWMN_0160
  • description: hypothetical protein
  • length: 518
  • theoretical pI: 8.26122
  • theoretical MW: 61046.4
  • GRAVY: -0.383591

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination sporulation integral membrane protein YtvI (TIGR02872; HMM-score: 16.6)
    Cellular processes Cellular processes Sporulation and germination anti-sigma F factor (TIGR01925; EC 2.7.11.1; HMM-score: 15.4)
    Signal transduction Regulatory functions Protein interactions anti-sigma F factor (TIGR01925; EC 2.7.11.1; HMM-score: 15.4)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, Spx/MgsR family (TIGR01617; HMM-score: 13.9)
    and 2 more
    Cellular processes Cellular processes Sporulation and germination stage II sporulation protein M (TIGR02831; HMM-score: 12.6)
    Cellular processes Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 12.4)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined His_kinase; Histidine kinase (PF06580; HMM-score: 76)
    and 10 more
    His_Kinase_A (CL0025) HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (PF02518; HMM-score: 25.8)
    no clan defined SIT; SHP2-interacting transmembrane adaptor protein, SIT (PF15330; HMM-score: 16.3)
    His_Kinase_A (CL0025) HATPase_c_2; Histidine kinase-like ATPase domain (PF13581; HMM-score: 14.5)
    no clan defined DUF2730; Protein of unknown function (DUF2730) (PF10805; HMM-score: 14.2)
    Tetraspannin (CL0347) Tetraspannin; Tetraspanin family (PF00335; HMM-score: 14.1)
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 13.9)
    no clan defined Spore_III_AB; Stage III sporulation protein AB (spore_III_AB) (PF09548; HMM-score: 13.7)
    Phage_barrel (CL0504) Phage-tail_3; Putative phage tail protein (PF13550; HMM-score: 13.1)
    no clan defined DUF4477; Domain of unknown function (DUF4477) (PF14780; HMM-score: 9.5)
    STAT_int; STAT protein, protein interaction domain (PF02865; HMM-score: 7.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.99
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001519
    • TAT(Tat/SPI): 0.000272
    • LIPO(Sec/SPII): 0.001285
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTAYKPYRHQLRRSLFASTIFPVFLVIIIGLVSFYAIYIWIEHRTIHQHVDESQSSLHHTEKQIQTFITQHNNSFQELDLTNHHDVTATKRELLKLIHQQPATLYYELSGPNQFITNNYEHLNTKNMYLFSTHQLKFKNSTYMLKIYMANTPRLSEIKKDNRQFALIVDQYDNILYANDDRFTIGEKYRPQQFGFMNESVKLNHADHRLIIYKDIHENIEDGITLLIVMAVVLVLLVIFGFISADNMAKRQTKDIETIIQKIYYAKNRHLGTYTPLKNNSELEEINNYIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTIQYLITLSPKLAQTVVQQLSQMLRYSLRTNSHTVELNEELNYIEQYVAIQNIRFDDMIKLHIESSEEARHQTIGKMMLQPLIENAIKHGRDTESLDITIRLTLARQNLHVLVCDNGIGMSSSRLQYVRQSLNNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYKIPLSRGNVDV

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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