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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_0388 [new locus tag: NWMN_RS02190 ]
- pan locus tag?: SAUPAN002104000
- symbol: set1nm
- pan gene symbol?: ssl1
- synonym:
- product: superantigen-like protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_0388 [new locus tag: NWMN_RS02190 ]
- symbol: set1nm
- product: superantigen-like protein
- replicon: chromosome
- strand: +
- coordinates: 436032..436712
- length: 681
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5330216 NCBI
- RefSeq: YP_001331422 NCBI
- BioCyc:
- MicrobesOnline: 3705919 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGAAATTTAAAGCGATAGCAAAAGCAAGTTTAGCATTGGGAATGTTAGCAACAGGTGTA
ATTACATCGAATGTACAATCAGTACAAGCGAAAGCAGAAGTTAAACAACAAAGTGAATCA
GAGTTAAAACACTATTATAATAAACCAATTTTAGAGCGTAAAAATGTGACTGGATTTAAA
TATACTGATGAGGGTAAACACTATTTAGAAGTCACAGTAGGGCAACAGCATTCTCGAATC
ACTTTACTTGGATCTGATAAAGATAAATTTAAAGACGGAGAAAACTCAAATATAGATGTG
TTTATCCTTAGAGAAGGTGACAGTAGACAAGCAACAAATTACTCAATTGGTGGCGTTACA
AAATCAAATAGTGTGCAGTATATTGATTATATCAATACGCCAATTTTAGAAATCAAGAAA
GATAATGAAGATGTACTTAAAGATTTTTACTACATTTCAAAAGAAGACATCTCATTAAAA
GAACTTGATTATAGATTAAGAGAACGTGCGATTAAACAACACGGCTTGTATTCAAATGGT
CTTAAACAAGGTCAAATTACAATTACAATGAATGATGGCACAACACATACAATCGATTTA
AGTCAAAAACTTGAAAAAGAACGTATGGGTGAGTCAATCGACGGCACTAAGATTAATAAA
ATTCTAGTAGAAATGAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_0388 [new locus tag: NWMN_RS02190 ]
- symbol: Set1nm
- description: superantigen-like protein
- length: 226
- theoretical pI: 9.02582
- theoretical MW: 25646.9
- GRAVY: -0.642035
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: OB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 110.1)and 2 moreAnt-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 21.6)MAP; MAP domain (PF03642; HMM-score: 14.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.14
- Cellwall Score: 0.16
- Extracellular Score: 9.7
- Internal Helices: 0
- LocateP: N-terminally anchored (with CS)
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: -0.17
- Signal peptide possibility: 1
- N-terminally Anchored Score: 3
- Predicted Cleavage Site: SVQAKAEV
- SignalP: Signal peptide SP(Sec/SPI) length 30 aa
- SP(Sec/SPI): 0.987487
- TAT(Tat/SPI): 0.007408
- LIPO(Sec/SPII): 0.004027
- Cleavage Site: CS pos: 30-31. VQA-KA. Pr: 0.5042
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKFKAIAKASLALGMLATGVITSNVQSVQAKAEVKQQSESELKHYYNKPILERKNVTGFKYTDEGKHYLEVTVGQQHSRITLLGSDKDKFKDGENSNIDVFILREGDSRQATNYSIGGVTKSNSVQYIDYINTPILEIKKDNEDVLKDFYYISKEDISLKELDYRLRERAIKQHGLYSNGLKQGQITITMNDGTTHTIDLSQKLEKERMGESIDGTKINKILVEMK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Stefan Monecke, Peter Slickers, Ralf Ehricht
Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition.
FEMS Immunol Med Microbiol: 2008, 53(2);237-51
[PubMed:18507678] [WorldCat.org] [DOI] (P p)