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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_1076 [new locus tag: NWMN_RS06100 ]
- pan locus tag?: SAUPAN003427000
- symbol: NWMN_1076
- pan gene symbol?: ssl13
- synonym:
- product: superantigen-like protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_1076 [new locus tag: NWMN_RS06100 ]
- symbol: NWMN_1076
- product: superantigen-like protein
- replicon: chromosome
- strand: -
- coordinates: 1179605..1180330
- length: 726
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5330662 NCBI
- RefSeq: YP_001332110 NCBI
- BioCyc:
- MicrobesOnline: 3706627 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
GCATCTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
ATAACAGGTGCAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
AACTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_1076 [new locus tag: NWMN_RS06100 ]
- symbol: NWMN_1076
- description: superantigen-like protein
- length: 241
- theoretical pI: 9.81625
- theoretical MW: 27364.6
- GRAVY: -0.643983
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 28)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 10
- Internal Helices: 0
- LocateP: N-terminally anchored (No CS)
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: -0.17
- Signal peptide possibility: 1
- N-terminally Anchored Score: 2
- Predicted Cleavage Site: No CleavageSite
- SignalP: Signal peptide SP(Sec/SPI) length 38 aa
- SP(Sec/SPI): 0.69993
- TAT(Tat/SPI): 0.006631
- LIPO(Sec/SPII): 0.265755
- Cleavage Site: CS pos: 38-39. AKA-YY. Pr: 0.2570
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Ilse Jongerius, Jörg Köhl, Manoj K Pandey, Maartje Ruyken, Kok P M van Kessel, Jos A G van Strijp, Suzan H M Rooijakkers
Staphylococcal complement evasion by various convertase-blocking molecules.
J Exp Med: 2007, 204(10);2461-71
[PubMed:17893203] [WorldCat.org] [DOI] (P p)