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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
  • pan locus tag?: SAUPAN001398000
  • symbol: NWMN_1912
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
  • symbol: NWMN_1912
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2121965..2123908
  • length: 1944
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGAAAATAAATAAGTTAACTATATCGAACTTTGCTGGAATCAAAGAAGTAACATTTAAC
    TTTGACGGTAAAGATGCAAAAATATACGGCAATAATGCGACTGGTAAGACTACAACAGCA
    ACCGCATTACAATGGCTGCTTTTCGATAAAGGTTTGGACGGATCAACCAAATCATTTAAC
    CCTGTACCTTTAAACGAAAAAAACGCAGAAAATTATGAGTTAATTCCGACTGTTTTCGCA
    GAATTTGAAATCGACGGAAAAATTACGACTTTTAAAAAAGAGTCACATCCTAAATACACA
    ATAAATCAAAAAACGAATCGCAAGGAATACTCACGAAGTCGAACGAAGAAACAATATATC
    AATGATGAATCAATAAAAGTAAAGGATTATAAAGCTCGTATTGATGAACTGATTGATGAA
    GATGTATTCAAGTTAATTACGAACCCTCAAGCATTTAACTTACTAGATTGGAAGAAGCGA
    AGAAGTTTGTTGTTTGAAATTGCTAAACCAATCAATGATGAGGATGTCATTAAAACAAAT
    GATGATTTTAAAGAATTAAATAATATTCTTGGAGATCATGAAATTGAAACAAAGAAAAAG
    ATTCTTACGGACAAGATAAAACAGATTAACAAAGATATCAAAGATATTCCGATACGTATT
    AACCAAACACAACAAAATAAGCAGGATGTACCAGAATTCGATAACGATAGATACGCAATT
    ATCAAACAAGAAATTGAGCAACTTGAAAATGAGCGTATAGATATTCAAAACGGTAAGGAA
    GAAATTAATTTGCGTAATCAATTAGCTGATAAACAATCAGAATTGAAACGCATAGAAGAC
    AATAACAGCGCAAGTAATGAGAACAAAATCCATGCTTTAACAAATGAATTACACGTTGAA
    AATGGAACGGTAGCAAACCTTAAAACGAGATTAAAGCAAAACAAACAACAAATCACACAT
    GAAGAAAATAGACGTAATCAATTATTGGAAAATCACAAAGGACTAAAAAGTGATTTAGAA
    AAATCTAAAAATCAAAAATTTGAACATCTTGATGACAATGTATGTAGTTGTTGTGGTCAA
    CAGTTACCAACTGAACAAGTGAATGAGGCAAGAGAAAAAGCTTTACAGAAATTCAATGTA
    AAAAAATCGAAAGAATTAGAAACAATACAAACATCTATCAATCACATTATTTCAGAAGGC
    AAGAAAATAAAGCCAATCATCGAGAAGTTAGAGGATGACAATAATAATCTTCAAATTAAA
    ATCAACGAAGCAGAAGAGCGTTCAGCAAGAATACAAAACAAAATTAATAAGTTGAAAACG
    ACTCACGTTGACGTTACGCAAACTGACGAATACAAAGCAGTAATGTTAGAGATAAATGAG
    ATTAATCAAAAACGCTCTAACATCAGGAAAACTATTCAAGATAAAGTTTCAGGAATAGAT
    GACAAAATAAGCGAACTTACTCAAGAAAAATCAGAAATTGAAGTGTCAAGATCAATCGAA
    AAATCAAATAAACATCTAGATGATGTTATTTCTGAATTAAGAAATGAAGAAGACAGATTA
    TTGGATGAAAAAGAAAAGTATTCACATGACCTTTATATCTTAAAAGAATTTACAACAACA
    AAAGTCAAAATGCTTACTGAAAATATCAATAACGAATTTGATATTGCTGAATTTAAGTTA
    TTCAATACCTTAGTTAACGGCGAATTAGAAGAAACATGTTCCACAACGGTTAACGGCGTC
    GAATACGACAGCGGTTTAAATAACGCCTCAAGAATTAATGTTGGCTTAGATATCATCAAT
    ACACTGTCAAAACATTTTAAAGTTACAGCACCAATATTTATTGATAATGCTGAATCAGTA
    ACAGAGCTTATCAAAACAGAATCACAACAAATTCAATTGATAGTAAATGAACAAGATAAA
    AAATTAAGAATGGAGACTATATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1944

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
  • symbol: NWMN_1912
  • description: hypothetical protein
  • length: 647
  • theoretical pI: 5.79129
  • theoretical MW: 74990.9
  • GRAVY: -0.888872

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 15.7)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 15.7)
    and 3 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 10.9)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 10.9)
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 9.2)
  • TheSEED: data available for USA300_FPR3757
  • PFAM:
    P-loop_NTPase (CL0023) AAA_23; AAA domain (PF13476; HMM-score: 38.9)
    and 6 more
    AAA_27; AAA domain (PF13514; HMM-score: 21.2)
    SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 19.7)
    no clan defined DUF3568; Protein of unknown function (DUF3568) (PF12092; HMM-score: 16.4)
    P-loop_NTPase (CL0023) AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 14.8)
    Reo_sigma (CL0326) Reo_sigmaC; Reovirus sigma C capsid protein (PF04582; HMM-score: 11.7)
    no clan defined DUF5347; Family of unknown function (DUF5347) (PF17282; HMM-score: 10.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.05577
    • TAT(Tat/SPI): 0.000764
    • LIPO(Sec/SPII): 0.001847
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKINKLTISNFAGIKEVTFNFDGKDAKIYGNNATGKTTTATALQWLLFDKGLDGSTKSFNPVPLNEKNAENYELIPTVFAEFEIDGKITTFKKESHPKYTINQKTNRKEYSRSRTKKQYINDESIKVKDYKARIDELIDEDVFKLITNPQAFNLLDWKKRRSLLFEIAKPINDEDVIKTNDDFKELNNILGDHEIETKKKILTDKIKQINKDIKDIPIRINQTQQNKQDVPEFDNDRYAIIKQEIEQLENERIDIQNGKEEINLRNQLADKQSELKRIEDNNSASNENKIHALTNELHVENGTVANLKTRLKQNKQQITHEENRRNQLLENHKGLKSDLEKSKNQKFEHLDDNVCSCCGQQLPTEQVNEAREKALQKFNVKKSKELETIQTSINHIISEGKKIKPIIEKLEDDNNNLQIKINEAEERSARIQNKINKLKTTHVDVTQTDEYKAVMLEINEINQKRSNIRKTIQDKVSGIDDKISELTQEKSEIEVSRSIEKSNKHLDDVISELRNEEDRLLDEKEKYSHDLYILKEFTTTKVKMLTENINNEFDIAEFKLFNTLVNGELEETCSTTVNGVEYDSGLNNASRINVGLDIINTLSKHFKVTAPIFIDNAESVTELIKTESQQIQLIVNEQDKKLRMETI

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]