PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 06-JUL-2013

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
• pan locus tag^?: SAUPAN001398000
• symbol: NWMN_1912
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
• symbol: NWMN_1912
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 2121965..2123908
• length: 1944
• essential: unknown

⊟Accession numbers

• Gene ID: 5331176 NCBI
• RefSeq: YP_001332946 NCBI
• BioCyc:
• MicrobesOnline: 3707500 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  1561
  1621
  1681
  1741
  1801
  1861
  1921
  
  ATGAAAATAAATAAGTTAACTATATCGAACTTTGCTGGAATCAAAGAAGTAACATTTAAC
  TTTGACGGTAAAGATGCAAAAATATACGGCAATAATGCGACTGGTAAGACTACAACAGCA
  ACCGCATTACAATGGCTGCTTTTCGATAAAGGTTTGGACGGATCAACCAAATCATTTAAC
  CCTGTACCTTTAAACGAAAAAAACGCAGAAAATTATGAGTTAATTCCGACTGTTTTCGCA
  GAATTTGAAATCGACGGAAAAATTACGACTTTTAAAAAAGAGTCACATCCTAAATACACA
  ATAAATCAAAAAACGAATCGCAAGGAATACTCACGAAGTCGAACGAAGAAACAATATATC
  AATGATGAATCAATAAAAGTAAAGGATTATAAAGCTCGTATTGATGAACTGATTGATGAA
  GATGTATTCAAGTTAATTACGAACCCTCAAGCATTTAACTTACTAGATTGGAAGAAGCGA
  AGAAGTTTGTTGTTTGAAATTGCTAAACCAATCAATGATGAGGATGTCATTAAAACAAAT
  GATGATTTTAAAGAATTAAATAATATTCTTGGAGATCATGAAATTGAAACAAAGAAAAAG
  ATTCTTACGGACAAGATAAAACAGATTAACAAAGATATCAAAGATATTCCGATACGTATT
  AACCAAACACAACAAAATAAGCAGGATGTACCAGAATTCGATAACGATAGATACGCAATT
  ATCAAACAAGAAATTGAGCAACTTGAAAATGAGCGTATAGATATTCAAAACGGTAAGGAA
  GAAATTAATTTGCGTAATCAATTAGCTGATAAACAATCAGAATTGAAACGCATAGAAGAC
  AATAACAGCGCAAGTAATGAGAACAAAATCCATGCTTTAACAAATGAATTACACGTTGAA
  AATGGAACGGTAGCAAACCTTAAAACGAGATTAAAGCAAAACAAACAACAAATCACACAT
  GAAGAAAATAGACGTAATCAATTATTGGAAAATCACAAAGGACTAAAAAGTGATTTAGAA
  AAATCTAAAAATCAAAAATTTGAACATCTTGATGACAATGTATGTAGTTGTTGTGGTCAA
  CAGTTACCAACTGAACAAGTGAATGAGGCAAGAGAAAAAGCTTTACAGAAATTCAATGTA
  AAAAAATCGAAAGAATTAGAAACAATACAAACATCTATCAATCACATTATTTCAGAAGGC
  AAGAAAATAAAGCCAATCATCGAGAAGTTAGAGGATGACAATAATAATCTTCAAATTAAA
  ATCAACGAAGCAGAAGAGCGTTCAGCAAGAATACAAAACAAAATTAATAAGTTGAAAACG
  ACTCACGTTGACGTTACGCAAACTGACGAATACAAAGCAGTAATGTTAGAGATAAATGAG
  ATTAATCAAAAACGCTCTAACATCAGGAAAACTATTCAAGATAAAGTTTCAGGAATAGAT
  GACAAAATAAGCGAACTTACTCAAGAAAAATCAGAAATTGAAGTGTCAAGATCAATCGAA
  AAATCAAATAAACATCTAGATGATGTTATTTCTGAATTAAGAAATGAAGAAGACAGATTA
  TTGGATGAAAAAGAAAAGTATTCACATGACCTTTATATCTTAAAAGAATTTACAACAACA
  AAAGTCAAAATGCTTACTGAAAATATCAATAACGAATTTGATATTGCTGAATTTAAGTTA
  TTCAATACCTTAGTTAACGGCGAATTAGAAGAAACATGTTCCACAACGGTTAACGGCGTC
  GAATACGACAGCGGTTTAAATAACGCCTCAAGAATTAATGTTGGCTTAGATATCATCAAT
  ACACTGTCAAAACATTTTAAAGTTACAGCACCAATATTTATTGATAATGCTGAATCAGTA
  ACAGAGCTTATCAAAACAGAATCACAACAAATTCAATTGATAGTAAATGAACAAGATAAA
  AAATTAAGAATGGAGACTATATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
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  660
  720
  780
  840
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  960
  1020
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  1140
  1200
  1260
  1320
  1380
  1440
  1500
  1560
  1620
  1680
  1740
  1800
  1860
  1920
  1944
  

⊟Protein

⊟General

• locus tag: NWMN_1912 [new locus tag: NWMN_RS11020 ]
• symbol: NWMN_1912
• description: hypothetical protein
• length: 647
• theoretical pI: 5.79129
• theoretical MW: 74990.9
• GRAVY: -0.888872

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 15.7)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 15.7)
  and 3 more
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 10.9)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 10.9)
  putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 9.2)
• TheSEED: data available for USA300_FPR3757
• PFAM:
  P-loop_NTPase (CL0023) AAA_23; AAA domain (PF13476; HMM-score: 38.9)
  and 6 more
  AAA_27; AAA domain (PF13514; HMM-score: 21.2)
  SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 19.7)
  no clan defined DUF3568; Protein of unknown function (DUF3568) (PF12092; HMM-score: 16.4)
  P-loop_NTPase (CL0023) AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 14.8)
  Reo_sigma (CL0326) Reo_sigmaC; Reovirus sigma C capsid protein (PF04582; HMM-score: 11.7)
  no clan defined DUF5347; Family of unknown function (DUF5347) (PF17282; HMM-score: 10.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: -1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.05577
  • TAT(Tat/SPI): 0.000764
  • LIPO(Sec/SPII): 0.001847
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 151222124 NCBI
• RefSeq: YP_001332946 NCBI
• UniProt: A0A0H3K9M0 UniProt

⊟Protein sequence

• MKINKLTISNFAGIKEVTFNFDGKDAKIYGNNATGKTTTATALQWLLFDKGLDGSTKSFNPVPLNEKNAENYELIPTVFAEFEIDGKITTFKKESHPKYTINQKTNRKEYSRSRTKKQYINDESIKVKDYKARIDELIDEDVFKLITNPQAFNLLDWKKRRSLLFEIAKPINDEDVIKTNDDFKELNNILGDHEIETKKKILTDKIKQINKDIKDIPIRINQTQQNKQDVPEFDNDRYAIIKQEIEQLENERIDIQNGKEEINLRNQLADKQSELKRIEDNNSASNENKIHALTNELHVENGTVANLKTRLKQNKQQITHEENRRNQLLENHKGLKSDLEKSKNQKFEHLDDNVCSCCGQQLPTEQVNEAREKALQKFNVKKSKELETIQTSINHIISEGKKIKPIIEKLEDDNNNLQIKINEAEERSARIQNKINKLKTTHVDVTQTDEYKAVMLEINEINQKRSNIRKTIQDKVSGIDDKISELTQEKSEIEVSRSIEKSNKHLDDVISELRNEEDRLLDEKEKYSHDLYILKEFTTTKVKMLTENINNEFDIAEFKLFNTLVNGELEETCSTTVNGVEYDSGLNNASRINVGLDIINTLSKHFKVTAPIFIDNAESVTELIKTESQQIQLIVNEQDKKLRMETI

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: NWMN_1911 < NWMN_1912 < NWMN_1913 < NWMN_1914 < NWMN_1915

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications