PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_1961 [new locus tag: SAUSA300_RS10755 ]
• pan locus tag^?: SAUPAN001398000
• symbol: SAUSA300_1961
• pan gene symbol^?: —
• synonym:
• product: phiPVL ORF41-like protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_1961 [new locus tag: SAUSA300_RS10755 ]
• symbol: SAUSA300_1961
• product: phiPVL ORF41-like protein
• replicon: chromosome
• strand: -
• coordinates: 2117652..2119607
• length: 1956
• essential: unknown

⊟Accession numbers

• Gene ID: 3913732 NCBI
• RefSeq: YP_494612 NCBI
• BioCyc: see SAUSA300_RS10755
• MicrobesOnline: 1293476 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

• 1
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  541
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  1141
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  ATGAGGAAGGATATGAAAATAAATAAATTAACAATATCGAACTTTGCCGGAATCAAAGAA
  GAAAAATTTAATTTTGACGGTAAAGATGCAAAAATATACGGCAATAATGCGACTGGTAAG
  ACTACAACAGCAACCGCATTACAATGGTTGCTTTTCGATAAAGGTTTGGACGGTTCAACC
  AAATCATTTAACCCTGTACCTTTAAACGAAAAAAACGAAGAAAATTATGAGTTAATTCCG
  ACTGTTTTCGCAGAATTTGAAATCGACGGAAAAATTACGACTTTTAAAAAAGAGTCACAT
  CCTAAATACACAATAAATCAAAAGACGAATCGCAAGGAATACTCACGAAGTCGAACGAAG
  AAACAATATATCAATGATGAATCAATAAAAGTAAAGGATTATAAAGCTCGTATTGATGAA
  CTTATTGATGAAGATGTATTCAAGTTAATTACGAACCCTCAAGCATTTAACTTACTAGAT
  TGGAAGAAGCGAAGAAGTTTGTTGTTTGAAATTGCTAAACCAATCAATGATGAGGATGTC
  ATTAAAACAAATGATGATTTTAAAGAACTAAATAATATTCTTGGAGATCATGAAATTGAA
  ACAAAGAAAAAGATTCTTACGGACAAGATAAAACAGATTAACAAAGATATCAAAGATATT
  CCGATACGTATTAACCAAACACAACAAAATAAGCAGGATGTACCAGAATTCGATAATGAT
  AGATACGCAATTATCAAACAAGAAATTGAGCAACTTGAAAATGAGCGTATAGATATTCAA
  AACGGTAAGGAAGAAATTAATTTACGTAATCAATTAGCTGATAAACAATCAGAATTGAAA
  CGCATAGAAGACAATAACAGCGCAAGTAATGAGAACAAAATCCATGCTTTAACAAATGAA
  TTACACGTTGAAAATGGAACGGTAGCAAACCTTAAAACGAGATTAAAGCAAAACAAACAA
  CAAATCACGCATGAAGAAAATAGACGTAATCAATTATTAGAAAATCATAAAGGATTAAAA
  AGTGATTTAGAAAAAGCTAAAAATCAAAAATTTGAATATCTTGATGACAATGTATGTAGT
  TGTTGTGGTCAAAAGTTACCAGTTGAACAAGTGGATATGGCAAGAGAAAAAGCATTGCAG
  AAATTCAATGCTAGCAAATCGAAAGAATTAGAAACAATACAAACATCTATCAATCACATT
  ATTTCAGAAGGCAAGAAAATAAAGCTAATCATCGAGAAGTTAGAGGATGACAATAATAAT
  CTTCAAATTAAAATCAACGAAGCAGAAGAGCGTTCAGCAAGAATACAAAACAAAATTAAT
  AAGTTGAAAACAACTCACGTTGACGTTACGCAAACTGACGAATACAAAGCAGTAATGTTA
  GAGATAAATGAGATTAATCAAAAACGCTCTAACATCAGGAAAACTATTCAAGATAAAGTT
  TCAGGAATAGATGACAAAATAAGCGAACTTACTCAAGAAAAATCAGAAATTGAAGTGTCA
  AGATCAATCGAAAAATCAAATAAACATCTAGATGATGTTATTTCTGAATTAAGAAATGAA
  GAAGACAGATTATTGGATGAAAAAGAAAAGTATTCACATGACCTTTATATCTTAAAAGAA
  TTTACAACAACAAAAGTCAAAATGCTTACTGAAAACATCAATAATGAATTTGAAATTGCT
  GAATTTAAGCTATTCAATACCTTAGTTAACGGCGAATTAGAAGAAACATGTTCCACAACG
  GTTAACGGCGTCGAATACGACAGCGGTTTAAATAACGCCTCAAGAATTAATGTTGGCTTA
  GATATCATCAATACACTGTCAAAACATTTTAAAGTTACAGCGCCAATATTTATTGATAAT
  GCTGAATCAGTAACAGAGCTTATCAAAACAGAATCACAACAAATTCAATTGATAGTAAAT
  GAACAAGATAAAAAATTAAGAATGGAGACTATATAA
  60
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  1956
  

⊟Protein

⊟General

• locus tag: SAUSA300_1961 [new locus tag: SAUSA300_RS10755 ]
• symbol: SAUSA300_1961
• description: phiPVL ORF41-like protein
• length: 651
• theoretical pI: 5.69722
• theoretical MW: 75608.7
• GRAVY: -0.892166

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 14.7)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 14.7)
  and 2 more
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 8.1)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 8.1)
• TheSEED  :
  • ATPase involved in DNA repair, phage associated
• PFAM:
  P-loop_NTPase (CL0023) AAA_23; AAA domain (PF13476; HMM-score: 26.9)
  AAA_27; AAA domain (PF13514; HMM-score: 22.6)
  and 7 more
  no clan defined DUF3568; Protein of unknown function (DUF3568) (PF12092; HMM-score: 18.4)
  P-loop_NTPase (CL0023) SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 18.2)
  AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 14.6)
  MukB; MukB N-terminal (PF04310; HMM-score: 12.1)
  Reo_sigma (CL0326) Reo_sigmaC; Reovirus sigma C capsid protein (PF04582; HMM-score: 9.9)
  no clan defined DUF5347; Family of unknown function (DUF5347) (PF17282; HMM-score: 9.1)
  P-loop_NTPase (CL0023) AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 6.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: -1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.051042
  • TAT(Tat/SPI): 0.002615
  • LIPO(Sec/SPII): 0.003952
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 87161143 NCBI
• RefSeq: YP_494612 NCBI
• UniProt: A0A0H2XI78 UniProt

⊟Protein sequence

• MRKDMKINKLTISNFAGIKEEKFNFDGKDAKIYGNNATGKTTTATALQWLLFDKGLDGSTKSFNPVPLNEKNEENYELIPTVFAEFEIDGKITTFKKESHPKYTINQKTNRKEYSRSRTKKQYINDESIKVKDYKARIDELIDEDVFKLITNPQAFNLLDWKKRRSLLFEIAKPINDEDVIKTNDDFKELNNILGDHEIETKKKILTDKIKQINKDIKDIPIRINQTQQNKQDVPEFDNDRYAIIKQEIEQLENERIDIQNGKEEINLRNQLADKQSELKRIEDNNSASNENKIHALTNELHVENGTVANLKTRLKQNKQQITHEENRRNQLLENHKGLKSDLEKAKNQKFEYLDDNVCSCCGQKLPVEQVDMAREKALQKFNASKSKELETIQTSINHIISEGKKIKLIIEKLEDDNNNLQIKINEAEERSARIQNKINKLKTTHVDVTQTDEYKAVMLEINEINQKRSNIRKTIQDKVSGIDDKISELTQEKSEIEVSRSIEKSNKHLDDVISELRNEEDRLLDEKEKYSHDLYILKEFTTTKVKMLTENINNEFEIAEFKLFNTLVNGELEETCSTTVNGVEYDSGLNNASRINVGLDIINTLSKHFKVTAPIFIDNAESVTELIKTESQQIQLIVNEQDKKLRMETI

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SAUSA300_1960 < SAUSA300_1961

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications