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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2051 [new locus tag: NWMN_RS11840 ]
  • pan locus tag?: SAUPAN005447000
  • symbol: NWMN_2051
  • pan gene symbol?: —
  • synonym:
  • product: lytic regulatory protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2051 [new locus tag: NWMN_RS11840 ]
  • symbol: NWMN_2051
  • product: lytic regulatory protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2268233..2269324
  • length: 1092
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    TTGTTTACTTACTTTAAATCAGCATTTAAAAATGCTAAACCACAATTATTAATAACATTG
    ATATATGCACTTATAGCATTTGCTGTAATTGCAGTTGTATATTTACTTGCTAATTTCCAG
    CTTGCTAAGTATGCACAAACTATTGCAATTTATTCACAATTTGGGCAAAAACCACCAGTA
    GATGCATATTTAAAAGTTATCGCTGTATTACTTATAGCAGCTGTAGTTTCACTGTTTGTT
    TTAGTTCAAATTTTTATCGGAATTACAAATGTTATGAAACGAGCAATGAGTCATGAAAAA
    GTAAAATTTACCGATTTATTTATTGCATTTAAAAAAGGTAATTATTTAAAGAGCGTTCTG
    ATCGGTCTTGTATCTATAGCAATGATTATCGTTCTTTCACTTCTGACATCATTACTATAC
    AAATTATTTTCTCCAGTATCAGAAATGATTATGAATTCAGTACAATCATCATATGCAGAT
    AGTACACACCTGATTGGTATTGCTATTACAACTCAAAGCATCATAATCATTGTTGTTTTA
    TTGATTAAAGCAATTATTACTTGGTTATTGTTAATACCTATTTTCAACTTTATGACTAGT
    TTCGTTGAATCAACTAACGATAAAGTAAAAACACACTTAGCTAATGGATTTAAAGCAATG
    AAAAATGGTCAAAAAACATTTTTCAAATTTTTCATTGGAATACTATTATTAAACTTAATT
    ATTATTTTATTTAAAACACCTGTTGGTTACTTGATTTCATTTAATACGCAATCACTCTCT
    CAAAGTGTTGCAGAAAATATCATAAGAGTTTATACAGTAATGACAATTATTTTATTCGTT
    GTTATTCATGCAATCATTTTAATGGGTATCGTTCAATATTACTTAAAACGTGGTCAAAAA
    ATTACTAAAGATAAAGTAAAAACAGCTGACAAGAATAAAAAAGTTGTCACTGAACCAAAA
    AATACAAAAGTAGAAAATGATAAAGTGACAACATCTGTTGAAACAAAAACAGAAAAAGCA
    CAAGATTCATTAAATGATAATACAACAAAAACAATGACTTCAGATAAACCAGAAGACAAT
    CAACCAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1092

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2051 [new locus tag: NWMN_RS11840 ]
  • symbol: NWMN_2051
  • description: lytic regulatory protein
  • length: 363
  • theoretical pI: 10.3916
  • theoretical MW: 40665.4
  • GRAVY: 0.528926

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 15.1)
    DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 15)
    MLANA; Protein melan-A (PF14991; HMM-score: 14.7)
    DUF975; Protein of unknown function (DUF975) (PF06161; HMM-score: 13.6)
    and 3 more
    Mucin; Mucin-like glycoprotein (PF01456; HMM-score: 9.1)
    Abhydrolase_9_N; Alpha/beta-hydrolase family N-terminus (PF15420; HMM-score: 7.6)
    DHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 6.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016051
    • TAT(Tat/SPI): 0.000434
    • LIPO(Sec/SPII): 0.00222
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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