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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2241 [new locus tag: NWMN_RS12915 ]
  • pan locus tag?: SAUPAN005834000
  • symbol: NWMN_2241
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2241 [new locus tag: NWMN_RS12915 ]
  • symbol: NWMN_2241
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2463934..2465166
  • length: 1233
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCATAAGTTTTGGGCGACATTTACTTTGACATATATCAAAAAAATTAAAGCTAAATCA
    TTTGTAATTTTTATGATTATTATTGCTGCCTTAATGATTGGCCTATCTAACATTGATAAG
    ATTATTAACATGTTTGATGATGGTCCAGATAAAATTGGTGTAGCAGCACCGAATGAACAA
    ATCTATAAGGTTTTCAAGCAACAGGCGAATACATTTCATAGTGATGCTAAGTTTACTAAA
    GTTTCTATAGAAGATGCTGAAAAAGAAGTAAAAAAACATAAACTTGATAAAGCTTATATT
    ATCAAGGTGAATCAAAATCGCACGTTACAAGGGACAATCATTAGTGAGAAGCGAGTAAGT
    CATGAAGATTCACAAAAAGTACAAGCACTGCTTACAGCTATTCAAACAAATATGGTAGCC
    GGGGAATTAAATATCAACAAAGAAGACTTACAAAAATTACAAGCACAAAGTAAAGTTGAT
    AATAAGGTGATTTCTAATGATGAAGTCGATAAAGTATCAGAAGGACAAAAGATTTTCAAC
    TATGCTTTAGCTTATGGCATTATCTTTCTAATGTTCTTCATTGTTTTAAATTATGCATCT
    CAAATAGCTATGGAAATTGCTAGTGAGAAAACATCGCGTGTCATTGAAATGATTATTACA
    AGTATTTCACCAATCCAACATATTTTTGCTAAAATTTTAGGCGTTATAGCAGTTGCCGTG
    ACTCAGATTATTTTAATTGTATTGATGGCAGTTATATGCATTTTTGCCTTTGACTTAAAA
    GACTTGCTACAAGGTTTTAACGTGGAAATGAATCAATTGTCTTGGCAAATTATTATTGTC
    GGAATTATAAGTAGTATTGTTGGAATTACGGCGTATGTATTACTTGCAGCCATCCTCGGA
    TCATTAACATCTAGAATAGAAGATTTAAATCAATCTTTGATGCCACTGACATTACTTGGT
    ATGATTGCATTTTATATCGCGATATTCACGATAAATAATCCTGATGGACAACTTGCTTTA
    ATCACAAGTTATATTCCGTTTTTAGCGCCATTTCAATTAGTTGTACGCGCTCAAACTTCA
    GGGCTTCAAATATATGAGGTCATCTTAAGTTCTTTAATCTCAATTGTAATGGTAGCTGTC
    TTGATATGGATTGCAATTAAAACATATAAAGATTCAGTACTTACATTTGAACGTGGCTTA
    TTTAATTCAATGAAACGTGTATTTAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1233

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_2241 [new locus tag: NWMN_RS12915 ]
  • symbol: NWMN_2241
  • description: hypothetical protein
  • length: 410
  • theoretical pI: 9.55044
  • theoretical MW: 45929.2
  • GRAVY: 0.48439

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis inosine-5'-monophosphate dehydrogenase (TIGR01302; EC 1.1.1.205; HMM-score: 13.4)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 167.8)
    and 3 more
    no clan defined ATP-gua_PtransN; ATP:guanido phosphotransferase, N-terminal domain (PF02807; HMM-score: 13.9)
    DUF502; Protein of unknown function (DUF502) (PF04367; HMM-score: 12.8)
    Abhydrolase_9_N; Alpha/beta-hydrolase family N-terminus (PF15420; HMM-score: 6.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.152211
    • TAT(Tat/SPI): 0.000814
    • LIPO(Sec/SPII): 0.142839
  • predicted transmembrane helices (TMHMM): 7

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MHKFWATFTLTYIKKIKAKSFVIFMIIIAALMIGLSNIDKIINMFDDGPDKIGVAAPNEQIYKVFKQQANTFHSDAKFTKVSIEDAEKEVKKHKLDKAYIIKVNQNRTLQGTIISEKRVSHEDSQKVQALLTAIQTNMVAGELNINKEDLQKLQAQSKVDNKVISNDEVDKVSEGQKIFNYALAYGIIFLMFFIVLNYASQIAMEIASEKTSRVIEMIITSISPIQHIFAKILGVIAVAVTQIILIVLMAVICIFAFDLKDLLQGFNVEMNQLSWQIIIVGIISSIVGITAYVLLAAILGSLTSRIEDLNQSLMPLTLLGMIAFYIAIFTINNPDGQLALITSYIPFLAPFQLVVRAQTSGLQIYEVILSSLISIVMVAVLIWIAIKTYKDSVLTFERGLFNSMKRVFKK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]