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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2252 [new locus tag: NWMN_RS12965 ]
  • pan locus tag?: SAUPAN005850000
  • symbol: NWMN_2252
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2252 [new locus tag: NWMN_RS12965 ]
  • symbol: NWMN_2252
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2473803..2474441
  • length: 639
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGACAAATCCAAATCAACGATTAGAACCATTTGATGAGACATTTCAACAACCGAATATT
    CATCGTGGTAAGCGATATGGTAAGAAAAAACGTTCATTGGTAAGCATGATTATTCAAATC
    ATTGTTGTTATATTAACCGCAATCGCTGGATACAGCATGTGGAAACAACCCATTTTTAAT
    ATTGTCTTCACCAAAGAATCTGTAGATTTTGATGGCATTAAAAATTTTAACGAGACAATT
    GGAAAAATGCATCAATTAAATATTAATTTGGGTAATATTAATGATTTACAACAAGGAATC
    GATCGCTTAATTTTAGTCTTTAACGGTTTCTTTATTTTATGTATCGTTAGCCTAGTCATA
    ACAATACTGACAATTGTATTTAATCGCACAGTTCTAAAAGTAGTAAATATTTTAGTGTTA
    ACAATTATGTTAGTCATTACATTGTATTTCAGTTATATTATTAAAGCACTCGCACAAGAA
    ATTGCAGATGTTTTCAAAAAATATTATTTAAATGTACCACCAGATCAAGTGATTACAGAA
    GCTGACGCTATTCATAACGGCATCATTTTACTTGGCTGTAGCATCGGTTTACTTGTTATA
    AGCTTATTCTTCCGTAATCGCATGCCTCGTTTAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    639

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2252 [new locus tag: NWMN_RS12965 ]
  • symbol: NWMN_2252
  • description: hypothetical protein
  • length: 212
  • theoretical pI: 10.0849
  • theoretical MW: 24257.8
  • GRAVY: 0.470755

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssB (TIGR03926; HMM-score: 9.3)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined TspO_MBR; TspO/MBR family (PF03073; HMM-score: 17.9)
    CopD_like (CL0430) DUF4149; Domain of unknown function (DUF4149) (PF13664; HMM-score: 15.3)
    and 8 more
    PH (CL0266) UCH_N; N-terminal of ubiquitin carboxyl-terminal hydrolase 37 (PF16674; HMM-score: 14)
    no clan defined DUF5362; Family of unknown function (DUF5362) (PF17319; HMM-score: 13.6)
    OppC_N; N-terminal TM domain of oligopeptide transport permease C (PF12911; HMM-score: 8.7)
    PKinase (CL0016) YukC; WXG100 protein secretion system (Wss), protein YukC (PF10140; HMM-score: 7.9)
    no clan defined DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 7.6)
    CobD_Cbib; CobD/Cbib protein (PF03186; HMM-score: 7.5)
    TMCCDC2; Transmembrane and coiled-coil domain-containing protein 2 (PF15844; HMM-score: 7.2)
    ATP_synt_H; ATP synthase subunit H (PF05493; HMM-score: 6.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010529
    • TAT(Tat/SPI): 0.000353
    • LIPO(Sec/SPII): 0.004481
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTNPNQRLEPFDETFQQPNIHRGKRYGKKKRSLVSMIIQIIVVILTAIAGYSMWKQPIFNIVFTKESVDFDGIKNFNETIGKMHQLNINLGNINDLQQGIDRLILVFNGFFILCIVSLVITILTIVFNRTVLKVVNILVLTIMLVITLYFSYIIKALAQEIADVFKKYYLNVPPDQVITEADAIHNGIILLGCSIGLLVISLFFRNRMPRLK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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