From AureoWiki
Jump to navigation Jump to search

NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2606 [new locus tag: NWMN_RS14925 ]
  • pan locus tag?: SAUPAN006480000
  • symbol: NWMN_2606
  • pan gene symbol?: mbtS
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2606 [new locus tag: NWMN_RS14925 ]
  • symbol: NWMN_2606
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2870910..2871479
  • length: 570
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    TTGAATCTGAGTAAACAAATTAAAAAGTATAGGGAACGAGATGGTTATTCACAAGAATAT
    CTTGCTGAAAAGTTATATGTATCTAGGCAGAGTATTTCTAATTGGGAAAATGACAAAAGC
    TTACCAGACATACATAACTTATTAATGATGTGTGAATTGTTCAATGTAACTTTAGATGAT
    TTAGTAAAAGGGACCATTCCATTTGTACCTGATATTAAAGCGCAACGAAGTCTTAACTTA
    TGGACATATGTGATGCTTATTTTCATGACATTAGCTGCAATTTTAATGGGACCTTTAGTT
    GTTTATTGGAATTGGACTTGGGGTGTAACGGTGGCAATCATTTTGGGAATAGGTTTTTAT
    GCATCTATGAAAATAGAAGATTTAAAAAAAGTGCATAAAATGGACAACTACGATCGAATT
    GTTGCTTTTATGAATGGAAAAGATCCTAGTGAAGTACAAACGACTAAAGCTAGAAATACG
    ATGACAAATGCGCTTTCTATTATATCAGTAATTGGTATACTCAGCCTCATAATTTTCCTT
    AGTGTGTATTTGGCAAATAAGTTTTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    570

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2606 [new locus tag: NWMN_RS14925 ]
  • symbol: NWMN_2606
  • description: hypothetical protein
  • length: 189
  • theoretical pI: 9.20529
  • theoretical MW: 21756.5
  • GRAVY: 0.18254

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 36.8)
    and 3 more
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 20.7)
    Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 20.6)
    integral membrane protein (TIGR04561; HMM-score: 7.8)
  • TheSEED  :
    • Transcriptional regulator, XRE family
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 61)
    and 10 more
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 48)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 32.1)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 25.1)
    Phage_CI_repr; Bacteriophage CI repressor helix-turn-helix domain (PF07022; HMM-score: 19.6)
    YdaS_toxin; Bacterial toxin YdaS (PF15943; HMM-score: 14.7)
    IT (CL0182) DctM; Tripartite ATP-independent periplasmic transporter, DctM component (PF06808; HMM-score: 13.7)
    HTH (CL0123) HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 13.5)
    HTH_11; HTH domain (PF08279; HMM-score: 13.1)
    no clan defined Attachment_P66; Borrelia burgdorferi attachment protein P66 (PF11263; HMM-score: 12.9)
    Pox_EPC_I2-L1; Poxvirus entry protein complex L1 and I2 (PF12575; HMM-score: 8.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.974
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0259
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005516
    • TAT(Tat/SPI): 0.000335
    • LIPO(Sec/SPII): 0.001107
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKAQRSLNLWTYVMLIFMTLAAILMGPLVVYWNWTWGVTVAIILGIGFYASMKIEDLKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNTMTNALSIISVIGILSLIIFLSVYLANKFL

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=NWMN_2606&oldid=73336"