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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS00620 [old locus tag: NWMN_0112 ]
  • pan locus tag?: SAUPAN001002000
  • symbol: NWMN_RS00620
  • pan gene symbol?:
  • synonym:
  • product: DUF454 domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS00620 [old locus tag: NWMN_0112 ]
  • symbol: NWMN_RS00620
  • product: DUF454 domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 136435..136818
  • length: 384
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (136435..136818) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0112

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGCGACTTATTTTAATCGTCATTGGCTTAATATTTACAGCGCTTGGTATTGCAGGTGCC
    GTATTACCTTTACTGCCAACGACCCCTTTTTTACTCGTAGCAGTTTTTTGTTTTGCTCGA
    AGTTCAGATCGCTTTTACAATTGGCTTATTAATCAAAAAATTTATAAAGAATATGTAGAA
    AACTTTTATTTACATCGAGGCTACACGCTACAACAGAAAATTAAAATTTTAATTAGCTTA
    TACATTGTAATAGGTTTTTCAATTTATATGGTGGATGTTCTTGCAGTCCGTGTAGGATTA
    ATCATAATGGTTATCATACAAACCGCTGTACTCTTTACATTTGTAAAAACATTACCCAAA
    TCAAATCATAAAATAGAGGAGTGA
    60
    120
    180
    240
    300
    360
    384

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS00620 [old locus tag: NWMN_0112 ]
  • symbol: NWMN_RS00620
  • description: DUF454 domain-containing protein
  • length: 127
  • theoretical pI: 9.99954
  • theoretical MW: 14569.6
  • GRAVY: 0.922047

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined DUF454; Protein of unknown function (DUF454) (PF04304; HMM-score: 127.5)
    and 3 more
    Glyoxalase (CL0104) Glyoxalase_2; Glyoxalase-like domain (PF12681; HMM-score: 16.7)
    no clan defined DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 13.1)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 5.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.132098
    • TAT(Tat/SPI): 0.018801
    • LIPO(Sec/SPII): 0.154716
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]