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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS02200 [old locus tag: NWMN_0390 ]
- pan locus tag?: SAUPAN002108000
- symbol: NWMN_RS02200
- pan gene symbol?: ssl3
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS02200 [old locus tag: NWMN_0390 ]
- symbol: NWMN_RS02200
- product: hypothetical protein
- replicon: chromosome
- strand: +
- coordinates: 437984..439042
- length: 1059
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1021ATGAAAATGAGAACAATTGCTAAAACCAGTTTAGCACTAGGGCTTTTAACAACAGGCGCA
ATTACAGTAACGACGCAATCGGTCAAAGCAGAAAAAATACAATCAACTAAAGTTGACAAA
GTACCAACGCTTAAAGCAGAGCGATTAGCAATGATAAACATAACAGCAGGTGCAAATTCA
GCGACAACACAAGCAGCTAACACAAGACAAGAACGCACGCCTAAACTCGAAAAGGCACCA
AATACTAATGAGGAAAAAACCTCAGCTTCCAAAATAGAAAAAATATCACAACCTAAACAA
GAAGAGCAGAAAACGCTTAATATATCAGCAACGCCAGCGCCTAAACAAGAACAATCACAA
ACGACAACCGAATCCACAACGCCGAAAACTAAAGTGACAACACCTCCATCAACAAACACG
CCACAACCAATGCAATCTACTAAATCAGACACACCACAATCTCCAACCATAAAACAAGCA
CAAACAGATATGACTCCTAAATATGAAGATTTAAGAGCGTATTATACAAAACCGAGTTTT
GAATTTGAAAAGCAGTTTGGATTTATGCTCAAACCATGGACGACGGTTAGGTTTATGAAT
GTTATTCCAAATAGGTTCATCTATAAAATAGCTTTAGTTGGAAAAGATGAGAAAAAATAT
AAAGATGGACCTTACGATAATATCGATGTATTTATCGTTTTAGAAGACAATAAATATCAA
TTGAAAAAATATTCTGTCGGTGGCATCACGAAGACTAATAGTAAAAAAGTTAATCACAAA
GTAGAATTAAGCATTACTAAAAAAGATAATCAAGGTATGATTTCACGCGATGTTTCAGAA
TACATGATTACTAAGGAAGAGATTTCCTTGAAAGAGCTTGATTTTAAATTGAGAAAACAA
CTTATTGAAAAACATAATCTTTACGGTAACATGGGTTCAGGAACAATCGTTATTAAAATG
AAAAACGGTGGGAAATATACGTTTGAATTACACAAAAAACTGCAAGAGCATCGTATGGCA
GGCACTAATATTGATAACATTGAAGTGAATATAAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS02200 [old locus tag: NWMN_0390 ]
- symbol: NWMN_RS02200
- description: hypothetical protein
- length: 352
- theoretical pI: 10.3256
- theoretical MW: 39738.4
- GRAVY: -0.778409
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin hydroxymethylbilane synthase (TIGR00212; EC 2.5.1.61; HMM-score: 11.6)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: OB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 111.9)and 5 moreAnt-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 31.2)PH (CL0266) bPH_2; Bacterial PH domain (PF03703; HMM-score: 12.3)no clan defined DUF4551; Protein of unknown function (DUF4551) (PF15087; HMM-score: 7.5)Ndc1_Nup; Nucleoporin protein Ndc1-Nup (PF09531; HMM-score: 7.1)Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 5.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0
- Extracellular Score: 10
- Internal Helices: 0
- LocateP:
- SignalP: Signal peptide SP(Sec/SPI) length 30 aa
- SP(Sec/SPI): 0.982026
- TAT(Tat/SPI): 0.003614
- LIPO(Sec/SPII): 0.009772
- Cleavage Site: CS pos: 30-31. VKA-EK. Pr: 0.9309
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKMRTIAKTSLALGLLTTGAITVTTQSVKAEKIQSTKVDKVPTLKAERLAMINITAGANSATTQAANTRQERTPKLEKAPNTNEEKTSASKIEKISQPKQEEQKTLNISATPAPKQEQSQTTTESTTPKTKVTTPPSTNTPQPMQSTKSDTPQSPTIKQAQTDMTPKYEDLRAYYTKPSFEFEKQFGFMLKPWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDVFIVLEDNKYQLKKYSVGGITKTNSKKVNHKVELSITKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKMKNGGKYTFELHKKLQEHRMAGTNIDNIEVNIK
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Stefan Monecke, Peter Slickers, Ralf Ehricht
Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition.
FEMS Immunol Med Microbiol: 2008, 53(2);237-51
[PubMed:18507678] [WorldCat.org] [DOI] (P p)