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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS03135 [old locus tag: NWMN_0546 ]
  • pan locus tag?: SAUPAN002361000
  • symbol: NWMN_RS03135
  • pan gene symbol?: —
  • synonym:
  • product: DUF423 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS03135 [old locus tag: NWMN_0546 ]
  • symbol: NWMN_RS03135
  • product: DUF423 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 629825..630193
  • length: 369
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (629825..630193) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0546

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAATTATTTATTATTTTAGGTGCATTAAACGCGATGATGGCTGTCGGTACAGGTGCA
    TTTGGTGCGCATGGTTTACAAGGAAAAATAAGTGATCACTATTTATCAGTATGGGAAAAA
    GCAACGACGTATCAAATGTACCATGGCTTAGCATTATTAATTATAGGTGTAATTAGTGGT
    ACAACTTCAATCAATGTTAACTGGGCTGGCTGGTTAATATTTGCTGGTATTATTTTCTTT
    AGTGGATCATTATATATTTTAGTATTAACTCAAATTAAAGTTTTAGGTGCGATTACGCCA
    ATTGGTGGCGTATTGTTCATCATTGGATGGATAATGTTAATCATTGCGACATTCAAATTT
    GCTGGTTAA
    60
    120
    180
    240
    300
    360
    369

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS03135 [old locus tag: NWMN_0546 ]
  • symbol: NWMN_RS03135
  • description: DUF423 domain-containing protein
  • length: 122
  • theoretical pI: 9.8831
  • theoretical MW: 13064.7
  • GRAVY: 1.15328

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined DUF423; Protein of unknown function (DUF423) (PF04241; HMM-score: 109.2)
    and 2 more
    DUF3917; Protein of unknown function (DUF3917) (PF13055; HMM-score: 12.7)
    ATP1G1_PLM_MAT8; ATP1G1/PLM/MAT8 family (PF02038; HMM-score: 8.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 25 aa
    • SP(Sec/SPI): 0.660095
    • TAT(Tat/SPI): 0.008896
    • LIPO(Sec/SPII): 0.069608
    • Cleavage Site: CS pos: 25-26. AHG-LQ. Pr: 0.3590
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKLFIILGALNAMMAVGTGAFGAHGLQGKISDHYLSVWEKATTYQMYHGLALLIIGVISGTTSINVNWAGWLIFAGIIFFSGSLYILVLTQIKVLGAITPIGGVLFIIGWIMLIIATFKFAG

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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