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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS03865 [old locus tag: NWMN_0684 ]
  • pan locus tag?: SAUPAN002601000
  • symbol: NWMN_RS03865
  • pan gene symbol?: pabC
  • synonym:
  • product: aminodeoxychorismate lyase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS03865 [old locus tag: NWMN_0684 ]
  • symbol: NWMN_RS03865
  • product: aminodeoxychorismate lyase
  • replicon: chromosome
  • strand: +
  • coordinates: 764439..765047
  • length: 609
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (764439..765047) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0684

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGCAATTATTTGAAACAATGAAAATTGATAATGGACATATCCCTAGACTTACTTATCAT
    ACTAATCGCATAAAATGTTCTTCTGAGCGATTAAACTTTAAATTTGATGAACATGCATGG
    CGAAATGAATTAAACGATGTAACAACAAAGTATCACAGTGGTCAATATAGACTTAAAATC
    GTATTAAATGCTGAAAGCAAATTTGAAACGATAGTGTCACCTTTACCTGAGAAAAGTAGT
    TTTACAGCAAAATTTCAAGTGTTGCCCAAAGTAGTTAATCCAACTTTTATAAAAAATAAA
    ACGACAGAACGAAAGCATTTAGCACACAATCATGAAACAGATTTAATATTGCTAACTTCA
    GAGGACGGCAAGGTCCTTGAATTTGATATTGGCAACATTGTCATTGAAGAGGATGGAAAA
    TGGTACACACCAAGTTATAAAGATGATTTCTTAAAAGGATGCATGCGTGATTATTTAATA
    GATAGTGACAAACTTGTTGAAAAAGACTTTAATAAAAACGAATTGATTTATAAATATCAT
    AACAATGAGATACGTTTATTTTTGATAAATAGTTTACGAGAGGTTGCCGATGTCCACCTT
    TGCCTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    609

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS03865 [old locus tag: NWMN_0684 ]
  • symbol: NWMN_RS03865
  • description: aminodeoxychorismate lyase
  • length: 202
  • theoretical pI: 7.01683
  • theoretical MW: 23840
  • GRAVY: -0.569802

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate lyase (TIGR03461; EC 4.1.3.38; HMM-score: 49.7)
    and 1 more
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01122; EC 2.6.1.42; HMM-score: 14.3)
  • TheSEED: data available for N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined Aminotran_4; Amino-transferase class IV (PF01063; HMM-score: 129.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00864
    • TAT(Tat/SPI): 0.00055
    • LIPO(Sec/SPII): 0.004618
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNELNDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTTERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLIDSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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