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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
- pan locus tag?: SAUPAN002791000
- symbol: NWMN_RS04285
- pan gene symbol?: vwb
- synonym:
- product: coagulase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
- symbol: NWMN_RS04285
- product: coagulase
- replicon: chromosome
- strand: +
- coordinates: 852779..854305
- length: 1527
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1501TTGAAAAATAAATTGCTAGTTTTATCATTGGGAGCATTATGTGTATCACAAATTTGGGAA
AGTAATCGTGCGAGTGCAGTGGTTTCTGGGGAGAAGAATCCATATGTATCTGAGTCGTTG
AAACTGACTAATAATAAAAATAAATCTAGAACAGTAGAAGAGTATAAGAAAAGCTTGGAT
GATTTAATATGGTCCTTTCCAAACTTAGATAATGAAAGATTTGATAATCCTGAATATAAA
GAAGCTATGAAAAAATATCAACAGAGATTTATGGCTGAAGATGAGGCTTTGAAGAAATTT
TTTAGTGAAGAGAAAAAAATAAAAAATGGAAATACTGATAATTTAGATTATCTAGGATTA
TCTCATGAAAGATATGAAAGTGTATTTAATACTTTGAAAAAACAAAGTGAGGAGTTCTTA
AAAGAAATTGAAGATATAAAAAAAGATAACCCTGAATTGAAAGACTTTAATGAAGAGGAG
CAATTAAAGTGCGACTTAGAATTAAACAAATTAGAAAATCAGATATTAATGTTAGGTAAA
ACATTTTATCAAAACTATAGAGATGATGTTGAAAGTTTATATAGTAAGTTAGATTTAATT
ATGGGATATAAAGATGAAGAAAGAGCAAATAAAAAAGCAGTTAACAAAAGGATGTTAGAA
AATAAAAAAGAAGACTTAGAAACCATAATTGATGAATTTTTTAGTGATATAGATAAAACA
AGACCTAATAATATTCCTGTTTTAGAAGATGAAAAACAAGAAGAGAAAAATCATAAAAAT
ATGGCTCAATTAAAATCTGACACTGAAGCAGCAAAAAGTGATGAATCAAAAAGAAGCAAG
AGAAGTAAAAGAAGTTTAAATACTCAAAATCACAAACCTGCATCTCAAGAAGTTTCTGAA
CAACAAAAAGCTGAATATGATAAAAGAGCAGAAGAAAGAAAAGCGAGATTTTTGGATAAT
CAAAAAATTAAGAAAACACCTGTAGTGTCATTAGAATATGATTTTGAGCATAAACAACGT
ATTGACAACGAAAACGACAAGAAACTTGTGGTTTCTGCACCAACAAAGAAACCAACATCA
CCGACTACATATACTGAAACAACGACACAGGTACCAATGCCTACAGTTGAGCGTCAAACT
CAGCAACAAATTATTTATAATGCACCAAAACAATTGGCTGGATTAAATGGTGAAAGTCAT
GATTTCACAACAACGCATCAATCACCAACAACTTCAAATCACACGCATAATAATGTTGTT
GAATTTGAAGAAACGTCTGCTTTACCTGGTAGAAAATCAGGATCACTGGTTGGTATAAGT
CAAATTGATTCTTCTCATCTAACTGAACGTGAGAAGCGTGTAATTAAGCGTGAACACGTT
AGAGAAGCTCAAAAGTTAGTTGATAATTATAAAGATACACATAGTTATAAAGACCGAATA
AATGCACAACAAAAAGTAAATACTTTAAGTGAAGGTCATCAAAAACGTTTTAATAAACAA
ATCAATAAAGTATATAATGGCAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
- symbol: NWMN_RS04285
- description: coagulase
- length: 508
- theoretical pI: 8.16958
- theoretical MW: 59277.8
- GRAVY: -1.18642
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: no clan defined Coagulase; Staphylococcus aureus coagulase (PF08764; HMM-score: 68.9)and 2 moreefb-c; Extracellular fibrinogen binding protein C terminal (PF12199; HMM-score: 7.8)EF-G-binding_N; Elongation factor G-binding protein, N-terminal (PF07299; HMM-score: 7.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0.1
- Cytoplasmic Membrane Score: 0.14
- Cellwall Score: 0.15
- Extracellular Score: 9.6
- Internal Helices: 0
- LocateP:
- SignalP: Signal peptide SP(Sec/SPI) length 26 aa
- SP(Sec/SPI): 0.974388
- TAT(Tat/SPI): 0.006156
- LIPO(Sec/SPII): 0.009697
- Cleavage Site: CS pos: 26-27. ASA-VV. Pr: 0.8573
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLDDLIWSFPNLDNERFDNPEYKEAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGLSHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEEQLKCDLELNKLENQILMLGKTFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKTRPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDNQKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRINAQQKVNTLSEGHQKRFNKQINKVYNGK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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