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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
  • pan locus tag?: SAUPAN002791000
  • symbol: NWMN_RS04285
  • pan gene symbol?: vwb
  • synonym:
  • product: coagulase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
  • symbol: NWMN_RS04285
  • product: coagulase
  • replicon: chromosome
  • strand: +
  • coordinates: 852779..854305
  • length: 1527
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (852779..854305) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0757

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    TTGAAAAATAAATTGCTAGTTTTATCATTGGGAGCATTATGTGTATCACAAATTTGGGAA
    AGTAATCGTGCGAGTGCAGTGGTTTCTGGGGAGAAGAATCCATATGTATCTGAGTCGTTG
    AAACTGACTAATAATAAAAATAAATCTAGAACAGTAGAAGAGTATAAGAAAAGCTTGGAT
    GATTTAATATGGTCCTTTCCAAACTTAGATAATGAAAGATTTGATAATCCTGAATATAAA
    GAAGCTATGAAAAAATATCAACAGAGATTTATGGCTGAAGATGAGGCTTTGAAGAAATTT
    TTTAGTGAAGAGAAAAAAATAAAAAATGGAAATACTGATAATTTAGATTATCTAGGATTA
    TCTCATGAAAGATATGAAAGTGTATTTAATACTTTGAAAAAACAAAGTGAGGAGTTCTTA
    AAAGAAATTGAAGATATAAAAAAAGATAACCCTGAATTGAAAGACTTTAATGAAGAGGAG
    CAATTAAAGTGCGACTTAGAATTAAACAAATTAGAAAATCAGATATTAATGTTAGGTAAA
    ACATTTTATCAAAACTATAGAGATGATGTTGAAAGTTTATATAGTAAGTTAGATTTAATT
    ATGGGATATAAAGATGAAGAAAGAGCAAATAAAAAAGCAGTTAACAAAAGGATGTTAGAA
    AATAAAAAAGAAGACTTAGAAACCATAATTGATGAATTTTTTAGTGATATAGATAAAACA
    AGACCTAATAATATTCCTGTTTTAGAAGATGAAAAACAAGAAGAGAAAAATCATAAAAAT
    ATGGCTCAATTAAAATCTGACACTGAAGCAGCAAAAAGTGATGAATCAAAAAGAAGCAAG
    AGAAGTAAAAGAAGTTTAAATACTCAAAATCACAAACCTGCATCTCAAGAAGTTTCTGAA
    CAACAAAAAGCTGAATATGATAAAAGAGCAGAAGAAAGAAAAGCGAGATTTTTGGATAAT
    CAAAAAATTAAGAAAACACCTGTAGTGTCATTAGAATATGATTTTGAGCATAAACAACGT
    ATTGACAACGAAAACGACAAGAAACTTGTGGTTTCTGCACCAACAAAGAAACCAACATCA
    CCGACTACATATACTGAAACAACGACACAGGTACCAATGCCTACAGTTGAGCGTCAAACT
    CAGCAACAAATTATTTATAATGCACCAAAACAATTGGCTGGATTAAATGGTGAAAGTCAT
    GATTTCACAACAACGCATCAATCACCAACAACTTCAAATCACACGCATAATAATGTTGTT
    GAATTTGAAGAAACGTCTGCTTTACCTGGTAGAAAATCAGGATCACTGGTTGGTATAAGT
    CAAATTGATTCTTCTCATCTAACTGAACGTGAGAAGCGTGTAATTAAGCGTGAACACGTT
    AGAGAAGCTCAAAAGTTAGTTGATAATTATAAAGATACACATAGTTATAAAGACCGAATA
    AATGCACAACAAAAAGTAAATACTTTAAGTGAAGGTCATCAAAAACGTTTTAATAAACAA
    ATCAATAAAGTATATAATGGCAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1527

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS04285 [old locus tag: NWMN_0757 ]
  • symbol: NWMN_RS04285
  • description: coagulase
  • length: 508
  • theoretical pI: 8.16958
  • theoretical MW: 59277.8
  • GRAVY: -1.18642

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined Coagulase; Staphylococcus aureus coagulase (PF08764; HMM-score: 68.9)
    and 2 more
    efb-c; Extracellular fibrinogen binding protein C terminal (PF12199; HMM-score: 7.8)
    EF-G-binding_N; Elongation factor G-binding protein, N-terminal (PF07299; HMM-score: 7.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.1
    • Cytoplasmic Membrane Score: 0.14
    • Cellwall Score: 0.15
    • Extracellular Score: 9.6
    • Internal Helices: 0
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 26 aa
    • SP(Sec/SPI): 0.974388
    • TAT(Tat/SPI): 0.006156
    • LIPO(Sec/SPII): 0.009697
    • Cleavage Site: CS pos: 26-27. ASA-VV. Pr: 0.8573
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNKLLVLSLGALCVSQIWESNRASAVVSGEKNPYVSESLKLTNNKNKSRTVEEYKKSLDDLIWSFPNLDNERFDNPEYKEAMKKYQQRFMAEDEALKKFFSEEKKIKNGNTDNLDYLGLSHERYESVFNTLKKQSEEFLKEIEDIKKDNPELKDFNEEEQLKCDLELNKLENQILMLGKTFYQNYRDDVESLYSKLDLIMGYKDEERANKKAVNKRMLENKKEDLETIIDEFFSDIDKTRPNNIPVLEDEKQEEKNHKNMAQLKSDTEAAKSDESKRSKRSKRSLNTQNHKPASQEVSEQQKAEYDKRAEERKARFLDNQKIKKTPVVSLEYDFEHKQRIDNENDKKLVVSAPTKKPTSPTTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRINAQQKVNTLSEGHQKRFNKQINKVYNGK

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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