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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS07625 [old locus tag: NWMN_1352 ]
  • pan locus tag?: SAUPAN003897000
  • symbol: NWMN_RS07625
  • pan gene symbol?: —
  • synonym:
  • product: PepSY domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS07625 [old locus tag: NWMN_1352 ]
  • symbol: NWMN_RS07625
  • product: PepSY domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1518212..1519552
  • length: 1341
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_009641 (1518212..1519552) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1352

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAAAAATACATTTAATCCATTACAAAGATTACATTTCTATGCAGCAATATTTATTGCT
    CCACTGTTAATCACTTTAACCATTTCGGGCATTGGTTACTTGTTCTTTCCAGAAGTTGAA
    AATAATATTTATAAGAATGAGTTTTTTGGTGACAGTGATGTAAAAACGCATCAAACATTA
    AATGATGCAGTACATCAAGTTGAACAACAATATGAAGGATTCTTTGTAAGTAAAGTTAGC
    ATACTTGATGAACCATATAACAAACGAATTACACTGAGTGATATGGCAGGAAATCAACGT
    TACGTCTTTCTAGATCATAACAATCAATTTGTTGCAGATCAAAATGCGAAACATACGTAT
    TCTAATGTGATGCGAAGTATACATAGTTCTTTGTTTACTGAAAATACTATTATTAATTAT
    TTAGTAGAGTTAACCGCATGTTGGATGATATTCATGATTTTATCTGGTACTTATTTACTC
    ATTAAGAAGCATTTAATTTCTAACAAAAGTAAGGCACTTCGTTGGCAAAAGTGGCACGCA
    ATGATTGGAGTTATCATTGCAATTCCAGTATTTGTATTAGTCTTAACTGGATTGCCATGG
    TCTGGTTTTATGGGCAGTAAAATTGCCGGTATGATGGACACAAACGGTGACCTTGGTCAA
    GGTGAATTAGCGATTAATCCACCTAAATCAGATTTGAACGAATTACCTTGGGCTACACGT
    AAAAATAAACAGCCAGCTTCATCCGAAAAAGGTTCAAGTGGTCATCATGGTAATGCAGCA
    ATGCCTCAAACCAAATTAGATTATCAAATATCTATTGATAAGGTCGTTGAACAGGCGCAA
    AAAGCTGGTATTAAAAAGCCGTTTTCAATCGTATATCCAAGTGATAAAAATGGTACCTTT
    ATTGTATCTAATACTAGTAATTCAGGTGTTACTGGGCTAGATGTATCACCATACAAGGAA
    CAAACACTTTATTTCGATCAATATAGCGGTAAAAAGCTAGGTACGATTAAATATGATGAC
    TACGGTATTATTGCTAAATGGTTTACATGGGGCATTCCGCTTCACGAAGGTCATTTATTC
    GGCATTTTAAATAAAATCATTAATTTATTTGTATGTATCGCTTTATTAGTAGCCATTGGC
    ATGGGGTTTGTCTCTTGGATAAAGCGTACAAAAAATACTGCAGTAAAAGTAACACATCGC
    GTAAAAAAACCAGCATCTATATCACTCATAATATGTTTAATTGTATTAGGATTATTAATG
    CCATTATTTGGATTATCACTTATCCTTGTATTTATAATTGAATTAATATTATATATTAAA
    GATCGTCGTGCTAAACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1341

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_RS07625 [old locus tag: NWMN_1352 ]
  • symbol: NWMN_RS07625
  • description: PepSY domain-containing protein
  • length: 446
  • theoretical pI: 9.75679
  • theoretical MW: 50205.2
  • GRAVY: 0.0769058

⊟Function[edit | edit source]

  • TIGRFAM:
    TIGR03943 family protein (TIGR03943; HMM-score: 10.9)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    PepSY_TM-like (CL0490) PepSY_TM; PepSY-associated TM region (PF03929; HMM-score: 177)
    and 6 more
    no clan defined SIT; SHP2-interacting transmembrane adaptor protein, SIT (PF15330; HMM-score: 12.2)
    Cyt_bd_oxida_II; Cytochrome bd terminal oxidase subunit II (PF02322; HMM-score: 11.2)
    Peptidase_A8; Signal peptidase (SPase) II (PF01252; HMM-score: 9.3)
    DUF1980; Domain of unknown function (DUF1980) (PF09323; HMM-score: 8.5)
    TctB; Tripartite tricarboxylate transporter TctB family (PF07331; HMM-score: 7.6)
    Cytochrom_B_C; Cytochrome b(C-terminal)/b6/petD (PF00032; HMM-score: 7.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.123574
    • TAT(Tat/SPI): 0.000974
    • LIPO(Sec/SPII): 0.036904
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNTFNPLQRLHFYAAIFIAPLLITLTISGIGYLFFPEVENNIYKNEFFGDSDVKTHQTLNDAVHQVEQQYEGFFVSKVSILDEPYNKRITLSDMAGNQRYVFLDHNNQFVADQNAKHTYSNVMRSIHSSLFTENTIINYLVELTACWMIFMILSGTYLLIKKHLISNKSKALRWQKWHAMIGVIIAIPVFVLVLTGLPWSGFMGSKIAGMMDTNGDLGQGELAINPPKSDLNELPWATRKNKQPASSEKGSSGHHGNAAMPQTKLDYQISIDKVVEQAQKAGIKKPFSIVYPSDKNGTFIVSNTSNSGVTGLDVSPYKEQTLYFDQYSGKKLGTIKYDDYGIIAKWFTWGIPLHEGHLFGILNKIINLFVCIALLVAIGMGFVSWIKRTKNTAVKVTHRVKKPASISLIICLIVLGLLMPLFGLSLILVFIIELILYIKDRRAKQ

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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