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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS10045 [old locus tag: NWMN_1757 ]
  • pan locus tag?: SAUPAN004845000
  • symbol: NWMN_RS10045
  • pan gene symbol?:
  • synonym:
  • product: aromatic acid exporter family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS10045 [old locus tag: NWMN_1757 ]
  • symbol: NWMN_RS10045
  • product: aromatic acid exporter family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1967572..1968666
  • length: 1095
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1967572..1968666) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1757

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    TTGAGACTAGGAGCTCGGATTTTTAAAACTGGTATAGCCATTATTTTAGCTATGTCTATC
    GCTTCTTTACTACCGGATGATGTTGGTCTGAAAGCCTTAGCTGGTGTCAGTGCTGTTGTT
    GCAATGCAACCTAGTATTTATCGTTCATTTAAAACAGTTTCTGATCAAGCATTGGGTAAC
    ATTATAGGTGCCATACTATCTGTTACAATGGTAACAATTTTTAGTGATAATTTTATCATT
    ATGGGTGTTACCGTCATAGTACTTATTGCTATTTTATTTAAATTTAATTTAGCACATGTT
    GCTACTTTGGCGAGTGTAACAGCATTAATCATTATGGGACAACATACCGGTTCTTTCTAT
    ATTACCGCCTTTTACAGGTTTGTACTTGTAATGATTGGTGTCATAAGTTCATCTCTAGTT
    AACTTTGTGTTTCTACCACCTAAATTTGAAACAAAAATTTACTATAATTCATTAAATATA
    TCCTCAGATATTTTTATGTGGTTTAAATTAGTATTAAATGATACGACGGAGTTTAATAAT
    ATTAAACAAGATAGTCATAATTTAAAACAACGTGTCGAAAAGTTAGAGAAAATTTATGAT
    TACTATAGCGAAGAACGTCCTATTACAAAAAAACATATTCACCAACAGAATAGAAAGAAA
    ATACTTTTCAGAGAAGTAGTTCAGACGACTAGACAAGCTTATGAAGTATTAAACAAATTG
    TCGCGTTATCAAAACGACTTATATTTACTTAATAACAATTTCCTATTACAAATCAAATTA
    GATTTAGATTCATTAACTGCTTTTCACGAGCAAATTTTAGCTAGCCTTTCTAAAAAAGCA
    CGTTATAATGTGACACATGTTGATTATGAGTTAGATAATCCGCAGAAAAAAGATTTATTG
    TCCACATTTCAGCATGAGTTAATAAATCATCCTTATCAAACGGAATATTCGTTTGCCAAT
    GTTATGCAAATTGTTGCAGCCATCGAAGAGTATCGACACCATTTAGAGCATTTAGACCGC
    ATAAGAATTAGCTTTTTCACATATCATAGATCTGATGCAGACATTGAAATTGTTGAAGAA
    GACTTTGATTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1095

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS10045 [old locus tag: NWMN_1757 ]
  • symbol: NWMN_RS10045
  • description: aromatic acid exporter family protein
  • length: 364
  • theoretical pI: 7.5245
  • theoretical MW: 41949.3
  • GRAVY: 0.112363

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    FUSC (CL0307) ArAE_1; Aromatic acid exporter family member 1 (PF06081; HMM-score: 95.3)
    and 5 more
    FUSC; Fusaric acid resistance protein family (PF04632; HMM-score: 41.9)
    FUSC_2; Fusaric acid resistance protein-like (PF13515; HMM-score: 34.6)
    no clan defined PspB; Phage shock protein B (PF06667; HMM-score: 13.7)
    Yip1 (CL0112) DUF1700; Protein of unknown function (DUF1700) (PF08006; HMM-score: 12.8)
    FUSC (CL0307) HPP; HPP family (PF04982; HMM-score: 6.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 34 aa
    • SP(Sec/SPI): 0.709662
    • TAT(Tat/SPI): 0.031413
    • LIPO(Sec/SPII): 0.026208
    • Cleavage Site: CS pos: 34-35. ALA-GV. Pr: 0.3770
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]