From AureoWiki
Jump to navigation Jump to search

NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0601
  • pan locus tag?: SAUPAN002524000
  • symbol: SA0601
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0601
  • symbol: SA0601
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 696464..697075
  • length: 612
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTACTTAACTATTCTTGTAACAATTCTTATTTCAATATTTTTGAGTTTAACAGAATCA
    TGGCAAGTAGAAACTGGAAACAGCATTGTGAATGCCATTTTTGGTGGTGTAAGCGTTGGA
    CTAGGAATCGGAGTAATTATCCTTGCAGGCGGTACAACAGCAGGTACAACAATTTTGGCG
    AGAATTGCAACGAAATACCTCGATGTAAGCACGCCATATGCTTTGCTTTTCTTCGATATG
    ATCGTTGTTGCAATTTCACTTACAGTTATTCCACTTGATAAAGTATTAGTAACAGTAATA
    TCACTTTATATAGGAACAAAAGTGATGGAATATGTCATAGAAGGTTTAAACACTAAAAAA
    GCTATGACGATTATTTCAACTAATCCCGACAAACTTGCCAAAGCAATAGACGAGCAAATT
    GGAAGAGGTTTAACCATTTTAAACGGACATGGCTATTATACGCGTGAAGAAAAAGATGTC
    TTATACGTTGTTATTTCTAAAACACAAGTTTCAAAAGCAAAGCGATTAATTAAACAAATC
    GATAAAGATGCATTCCTCGTAATTCATGATGTAAGAGATGTCTATGGTAATGGCTTTCTT
    GCAGATGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    612

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0601
  • symbol: SA0601
  • description: hypothetical protein
  • length: 203
  • theoretical pI: 6.53798
  • theoretical MW: 22087.8
  • GRAVY: 0.57734

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • UPF0750 membrane protein YxkD
  • PFAM:
    no clan defined YitT_membrane; Uncharacterised 5xTM membrane BCR, YitT family COG1284 (PF02588; HMM-score: 120.4)
    and 2 more
    GlnB-like (CL0089) DUF2179; Uncharacterized protein conserved in bacteria (DUF2179) (PF10035; HMM-score: 78)
    P-loop_NTPase (CL0023) KAP_NTPase; KAP family P-loop domain (PF07693; HMM-score: 11.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.349444
    • TAT(Tat/SPI): 0.000743
    • LIPO(Sec/SPII): 0.047562
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MYLTILVTILISIFLSLTESWQVETGNSIVNAIFGGVSVGLGIGVIILAGGTTAGTTILARIATKYLDVSTPYALLFFDMIVVAISLTVIPLDKVLVTVISLYIGTKVMEYVIEGLNTKKAMTIISTNPDKLAKAIDEQIGRGLTILNGHGYYTREEKDVLYVVISKTQVSKAKRLIKQIDKDAFLVIHDVRDVYGNGFLADE

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: CodY (repression) regulon
    CodY(TF)important in Amino acid metabolism; RegPrecise 

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]