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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1091 [new locus tag: SA_RS06180 ]
  • pan locus tag?: SAUPAN003542000
  • symbol: fmhC
  • pan gene symbol?: fmhC
  • synonym:
  • product: FmhC protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA1091 [new locus tag: SA_RS06180 ]
  • symbol: fmhC
  • product: FmhC protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1234728..1235972
  • length: 1245
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAATTTTCAACTTTAAGTGAAGAAGAATTTACCAACTACACCAAAAAGCACTTCAAA
    CATTATACACAGTCTATAGAATTATATAATTATAGAAATAAAATAAATCATGAAGCACAT
    ATTGTGGGAGTGAAGAATGATAAAAATGAAGTTATAGCTGCATGTTTATTAACAGAGGCA
    CGAATTTTTAAATTCTACAAATATTTCTACTCTCATAGAGGTCCTTTACTTGATTATTTC
    GATGCTAAATTAGTTTGTTACTTTTTTAAAGAATTATCTAAATTCATTTATAAAAATAGA
    GGAGTATTTATTCTTGTTGATCCATATTTAATAGAGAATTTAAGAGATGCAAATGGTAGG
    ATAATAAAGAATTATAATAATTCAGTGATAGTAAAGATGCTAGGGAAAATTGGGTATCTC
    CATCAAGGTTATACAACAGGATATTCAAATAAAAGTCAAATTAGGTGGATTTCTGTATTG
    GATTTAAAAGATAAAGATGAGAATCAACTTTTAAAAGAAATGGAATACCAAACTAGAAGA
    AATATAAAAAAGACTATTGAGATTGGTGTTAAGGTTGAAGATTTATCTATTGAAGAAACA
    AATCGATTTTATAAATTGTTTCAAATGGCTGAAGAAAAACATGGTTTTCATTTCATGAAT
    GAAGATTATTTTAAACGAATGCAAGAAATATATAAAGATAAGGCAATGTTAAAGATAGCT
    TGTATAAATCTTAATGAATATCAAGATAAATTAAAAATACAATTATTGAAAATCGAAAAT
    GAAATGATGACTGTGAACAGAGCATTAAATGAAAATCCAAATTCTAAAAAGAATAAATCA
    AAATTAAATCAGTTAAATATGCAATTATCTAGTATTAATAATAGAATTAGTAAAACCGAA
    GAACTAATATTAGAAGATGGACCTGTTTTGGATTTAGCTGCTGCTTTATTTATATGTACT
    GATGATGAAGTTTATTATCTATCAAGTGGATCAAATCCGAAATATAATCAGTATATGGGT
    GCATATCATCTACAATGGCATATGATAAAATATGCAAAATCACATAATATTAATAGGTAT
    AATTTTTATGGAATAACAGGCGTCTTTAGTAATGAGGCGGATGATTTTGGTGTTCAACAA
    TTTAAAAAGGGTTTTAATGCACATGTTGAAGAATTAATTGGTGATTTCATCAAACCAGTA
    AGACCAATTCTATATAAATTTGCAAAACTTATTTATAAGGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1245

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA1091 [new locus tag: SA_RS06180 ]
  • symbol: FmhC
  • description: FmhC protein
  • length: 414
  • theoretical pI: 9.38877
  • theoretical MW: 49082.2
  • GRAVY: -0.517391

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General FemAB-related protein, PEP-CTERM system-associated (TIGR03019; HMM-score: 23)
  • TheSEED  :
    • FmhC protein of FemAB family
  • PFAM:
    Acetyltrans (CL0257) FemAB; FemAB family (PF02388; HMM-score: 487.5)
    and 4 more
    Acetyltransf_6; Acetyltransferase (GNAT) domain (PF13480; HMM-score: 24.7)
    P-loop_NTPase (CL0023) DUF3584; Protein of unknown function (DUF3584) (PF12128; HMM-score: 17.6)
    no clan defined LRRFIP; LRRFIP family (PF09738; HMM-score: 14.5)
    Cob_adeno_trans (CL0601) Cob_adeno_trans; Cobalamin adenosyltransferase (PF01923; HMM-score: 13.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013322
    • TAT(Tat/SPI): 0.000284
    • LIPO(Sec/SPII): 0.002296
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELILEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]