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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1617 [new locus tag: SA_RS09095 ]
  • pan locus tag?: SAUPAN004514000
  • symbol: SA1617
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA1617 [new locus tag: SA_RS09095 ]
  • symbol: SA1617
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1851734..1852348
  • length: 615
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    TTGAATACAGAGAACAACAAGAATCAAAACCAATCTGTTAAAAATTCTGAAAGACGCGGC
    ATGTTAAAAGGATGCGGCGGTTGCCTTATTTCTTTTATTTTATTAATAATCTTATTATCA
    GCCTGTTCAATGATGTTTAGTAATAATGACAATTCCACTAGTAATCAATCATCAAAAACG
    CAATTAACTCAAAAAGATGAAAATAAAAATGAAGATAAGCCTGAGGAAAAATCAGAAACA
    GCTACAGATGAGGATTTACAATCAACCGAAGAAGTACCCGCAAATGAAAATACTGAAAAT
    AATCAACATGAAATTGATGAAATAACAACAAAAGATCAATCAGATGATGAAATTAACACA
    CCAAACGTTGCAGAAGATAAATCACAAGACGACTTGAAAGATGATTTAAAAGAAAAGCAA
    CAATCAAGTAACCATCATCAATCCACGCAACCTAAGACCTCACCATCAACTGAAACAAAC
    AGGCAACAATCATTTGCTAATTGTAAGCAACTTAGACAAGTTTATCCGAATGGTGTCACT
    GCCGATCATCCAGCATATCGTCCACATTTAGATAGAGATAAAGATAATCGTGCATGTGAA
    CCTGATAAAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    615

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA1617 [new locus tag: SA_RS09095 ]
  • symbol: SA1617
  • description: hypothetical protein
  • length: 204
  • theoretical pI: 4.51774
  • theoretical MW: 23073.7
  • GRAVY: -1.44853

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis putative immunoglobulin-blocking virulence protein (TIGR04526; HMM-score: 16.6)
    Cellular processes Cellular processes Pathogenesis type III secretion protein, HrcV family (TIGR01399; HMM-score: 14.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion protein, HrcV family (TIGR01399; HMM-score: 14.4)
    TIGR03943 family protein (TIGR03943; HMM-score: 13.5)
    and 11 more
    Cellular processes Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 11.4)
    Cellular processes Cellular processes Cell division cell division protein ZipA (TIGR02205; HMM-score: 10.1)
    mycoides cluster lipoprotein, LppA/P72 family (TIGR03490; HMM-score: 9.1)
    type IV conjugative transfer system protein TraV (TIGR02747; HMM-score: 8.5)
    Cellular processes Cellular processes Sporulation and germination stage III sporulation protein AF (TIGR02896; HMM-score: 7.4)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 5.9)
    Metabolism Transport and binding proteins Nucleosides, purines and pyrimidines nucleoside Transporter (TIGR00939; HMM-score: 5.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssA (TIGR03927; HMM-score: 4.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds potassium uptake protein, Trk family (TIGR00934; HMM-score: 3.8)
    Metabolism Energy metabolism TCA cycle dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex (TIGR01347; EC 2.3.1.61; HMM-score: 3.6)
    Metabolism Transport and binding proteins Cations and iron carrying compounds K+-dependent Na+/Ca+ exchanger (TIGR00927; HMM-score: 1.6)
  • TheSEED:  
    Hypothetical protein SAV1799
  • PFAM:
    no clan defined Excalibur; Excalibur calcium-binding domain (PF05901; HMM-score: 46.3)
    and 19 more
    DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 17.1)
    Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain (PF12166; HMM-score: 16.4)
    CRA; Circumsporozoite-related antigen (CRA) (PF06589; HMM-score: 16.3)
    TMEM51; Transmembrane protein 51 (PF15345; HMM-score: 14.7)
    DUF4775; Domain of unknown function (DUF4775) (PF16001; HMM-score: 12.8)
    Viral_ssRNA_CP (CL0055) TT_ORF1; TT viral orf 1 (PF02956; HMM-score: 11.6)
    no clan defined FAM176; FAM176 family (PF14851; HMM-score: 10.3)
    O-anti_assembly (CL0499) O-antigen_lig; O-antigen ligase like membrane protein (PF13425; HMM-score: 10)
    AhpD-like (CL0423) PA26; PA26 p53-induced protein (sestrin) (PF04636; HMM-score: 9.8)
    DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 9.7)
    no clan defined SAPS; SIT4 phosphatase-associated protein (PF04499; HMM-score: 8.7)
    DUF4692; Domain of unknown function (DUF4692) (PF15763; HMM-score: 8.4)
    SLC12; Solute carrier family 12 (PF03522; HMM-score: 7.7)
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain (PF14575; HMM-score: 7.5)
    GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 6.9)
    no clan defined G0-G1_switch_2; G0/G1 switch protein 2 (PF15103; HMM-score: 6.9)
    Raftlin; Raftlin (PF15250; HMM-score: 6.7)
    Golgi_traff (CL0456) Hid1; High-temperature-induced dauer-formation protein (PF12722; HMM-score: 6.4)
    no clan defined WDCP; WD repeat and coiled-coil-containing protein family (PF15390; HMM-score: 5.3)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: LLSACSM
  • SignalP: Signal peptide LIPO(Sec/SPII) length 41 aa
    • SP(Sec/SPI): 0.006756
    • TAT(Tat/SPI): 0.038364
    • LIPO(Sec/SPII): 0.940553
    • Cleavage Site: CS pos: 41-42. LSA-CS. Pr: 0.8979
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNTENNKNQNQSVKNSERRGMLKGCGGCLISFILLIILLSACSMMFSNNDNSTSNQSSKTQLTQKDENKNEDKPEEKSETATDEDLQSTEEVPANENTENNQHEIDEITTKDQSDDEINTPNVAEDKSQDDLKDDLKEKQQSSNHHQSTQPKTSPSTETNRQQSFANCKQLRQVYPNGVTADHPAYRPHLDRDKDNRACEPDKN

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

  • SA1617 no polycistronic organisation predicted

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]