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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS09095 [old locus tag: SA1617 ]
  • pan locus tag?: SAUPAN004514000
  • symbol: SA_RS09095
  • pan gene symbol?: —
  • synonym:
  • product: calcium-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS09095 [old locus tag: SA1617 ]
  • symbol: SA_RS09095
  • product: calcium-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1851698..1852348
  • length: 651
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1851698..1852348) NCBI
  • BioCyc: SA_RS09095 BioCyc
  • MicrobesOnline: see SA1617

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGAAAATAACATATAAATATAGAGGAGATTTACCTTTGAATACAGAGAACAACAAGAAT
    CAAAACCAATCTGTTAAAAATTCTGAAAGACGCGGCATGTTAAAAGGATGCGGCGGTTGC
    CTTATTTCTTTTATTTTATTAATAATCTTATTATCAGCCTGTTCAATGATGTTTAGTAAT
    AATGACAATTCCACTAGTAATCAATCATCAAAAACGCAATTAACTCAAAAAGATGAAAAT
    AAAAATGAAGATAAGCCTGAGGAAAAATCAGAAACAGCTACAGATGAGGATTTACAATCA
    ACCGAAGAAGTACCCGCAAATGAAAATACTGAAAATAATCAACATGAAATTGATGAAATA
    ACAACAAAAGATCAATCAGATGATGAAATTAACACACCAAACGTTGCAGAAGATAAATCA
    CAAGACGACTTGAAAGATGATTTAAAAGAAAAGCAACAATCAAGTAACCATCATCAATCC
    ACGCAACCTAAGACCTCACCATCAACTGAAACAAACAGGCAACAATCATTTGCTAATTGT
    AAGCAACTTAGACAAGTTTATCCGAATGGTGTCACTGCCGATCATCCAGCATATCGTCCA
    CATTTAGATAGAGATAAAGATAATCGTGCATGTGAACCTGATAAAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    651

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS09095 [old locus tag: SA1617 ]
  • symbol: SA_RS09095
  • description: calcium-binding protein
  • length: 216
  • theoretical pI: 4.66533
  • theoretical MW: 24522.4
  • GRAVY: -1.40972

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis putative immunoglobulin-blocking virulence protein (TIGR04526; HMM-score: 16.4)
    Cellular processes Cellular processes Pathogenesis type III secretion protein, HrcV family (TIGR01399; HMM-score: 14.1)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion protein, HrcV family (TIGR01399; HMM-score: 14.1)
    TIGR03943 family protein (TIGR03943; HMM-score: 13.3)
    and 9 more
    Cellular processes Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 11.2)
    Cellular processes Cellular processes Cell division cell division protein ZipA (TIGR02205; HMM-score: 10)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 7.2)
    Cellular processes Cellular processes Sporulation and germination stage III sporulation protein AF (TIGR02896; HMM-score: 5.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids 3-hydroxy-3-methylglutaryl-coenzyme A reductase (TIGR00920; HMM-score: 5.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds potassium uptake protein, Trk family (TIGR00934; HMM-score: 4.8)
    Metabolism Transport and binding proteins Nucleosides, purines and pyrimidines nucleoside Transporter (TIGR00939; HMM-score: 4)
    Metabolism Energy metabolism TCA cycle dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex (TIGR01347; EC 2.3.1.61; HMM-score: 3.4)
    Metabolism Transport and binding proteins Cations and iron carrying compounds K+-dependent Na+/Ca+ exchanger (TIGR00927; HMM-score: 1.8)
  • TheSEED: see SA1617
  • PFAM:
    no clan defined Excalibur; Excalibur calcium-binding domain (PF05901; HMM-score: 48.2)
    and 13 more
    CRA; Circumsporozoite-related antigen (CRA) (PF06589; HMM-score: 17.8)
    FAM176; FAM176 family (PF14851; HMM-score: 15.5)
    DUF5850; Family of unknown function (DUF5850) (PF19168; HMM-score: 13.9)
    Nucleoplasmin (CL0055) TT_ORF1; TT viral orf 1 (PF02956; HMM-score: 10.7)
    no clan defined Ac45-VOA1_TM; V0 complex accessory subunit Ac45/VOA1 transmembrane domain (PF20520; HMM-score: 9.6)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 9.5)
    GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 9.4)
    no clan defined CCSAP; Centriole, cilia and spindle-associated (PF15748; HMM-score: 7.8)
    DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 7.7)
    AhpD-like (CL0423) PA26; PA26 p53-induced protein (sestrin) (PF04636; HMM-score: 7.5)
    no clan defined PFF1_TM; Vacuolar membrane protease, transmembrane domain (PF22251; HMM-score: 7.5)
    Golgi_traff (CL0456) Hid1; High-temperature-induced dauer-formation protein (PF12722; HMM-score: 6.5)
    no clan defined Macoilin; Macoilin family (PF09726; HMM-score: 5.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.3866
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.6133
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 53 aa
    • SP(Sec/SPI): 0.042232
    • TAT(Tat/SPI): 0.01563
    • LIPO(Sec/SPII): 0.686594
    • Cleavage Site: CS pos: 53-54. LSA-CS. Pr: 0.5997
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKITYKYRGDLPLNTENNKNQNQSVKNSERRGMLKGCGGCLISFILLIILLSACSMMFSNNDNSTSNQSSKTQLTQKDENKNEDKPEEKSETATDEDLQSTEEVPANENTENNQHEIDEITTKDQSDDEINTPNVAEDKSQDDLKDDLKEKQQSSNHHQSTQPKTSPSTETNRQQSFANCKQLRQVYPNGVTADHPAYRPHLDRDKDNRACEPDKN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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