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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1766 [new locus tag: SA_RS10155 ]
  • pan locus tag?: SAUPAN005048000
  • symbol: SA1766
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA1766 [new locus tag: SA_RS10155 ]
  • symbol: SA1766
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2018761..2023290
  • length: 4530
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    ATGGGAGAAAGAATAAAAGGTTTATCTATAGGTTTGGATTTAGATGCAGCAAATTTAAAT
    AGATCATTTGCAGAAATCAAACGAAACTTTAAAACTTTAAATTCTGACTTAAAGTTAACC
    GGTAACAACTTCAAATATACCGAAAAATCAACTCATAGTTACAAACAAAGGATTAAAGAA
    CTTGATGGAACTATCACAGGTTATAAGAAAAACGTTGATGATTTAGCCAAGCAATATGGC
    AAGGTATCTCAAGAACAGGGCGAAAACAGCGCGGAAGCTCAAAAATTACGACAAGAATAT
    AACAAACAAGCAAATGAGCTGAATTTTTTAGAAAAAGAACTAGAAAAAACAACAACTGAG
    TTTGAAGAGTTCAAAAAAGCTCAAGTTGAAGCTCAAAGAATGGCAGAAAGTGGCTGGGGA
    AAAACCAGTAAAGTTTTTGAAAGTATGGGACCTAAATTAACAAAAATGGGTGATGGTTTA
    AAATCCATTGGTAAAGGTTTGATGATTGGTGTAACTGCACCTGTTTTAGGTATTGCAGCA
    GCATCAGGAAAAGCTTTTGCAGAAGTTGATAAAGGTTTAGATACAGTTACCCAAGCAACA
    GGAGCAACCGGCGGAGAGCTTAAGAAGTTGCAGAATTCATTTAAAGATGTTTATGGCAAC
    TTTCCAGAAGACGCTGAGACTGTAGGCGGTGTTTTAGGGGAAGTTAACACAAGGTTAGGT
    TTCACTGGCAAAGAACTTGAGAGTGCCACAGAGTCATTCTTGAAATTTAGTCACATAACA
    GGTTCTGACGGCGTACAAGCCGTTCAATTAATTACGCGTGCAATGGGTGATGCAGGTATT
    GAAGCTGATGAGTATCAAAGTGTACTTGATATGGTAGCGAAAGCAGCACAGGCTAGCGGT
    ATAAGTGTTGATACATTAGCTGATAGCATTACTAAATACGGTGCTCCAATGAGGGCTATG
    GGCTTTGAGATGAAAGAATCAATCGCTTTATTCTCTCAATGGGAGAAATCAGGTGTTAAT
    ACTGAAATAGCCTTCAGTGGTTTGAAAAAAGCTATATCCAATTGGGGTAAAGCGGGTAAA
    GACCCAAGAGAAGAATTTAAGAAGACATTAGCAGAAATTGAAAGGACACCGGATATAGCT
    AGCGCAACAAGTTTAGCGATTGAAGCATTTGGTGCAAAAGCAGGTCCTGATTTAGCAGAT
    GCTATTAAAGGCGGTCGCTTTAGTTACCAAGAGTTCTTAAAAACTATCGAAGATTCGCAA
    GGAACGGTCAATCAGACATTTAAAGATTCTGAAAGTGGCTCCGAAAGATTTAAAGTAGCA
    ATGAATAAACTTAAATTAGTAGGTGCTGATGTATGGGCTTCTATTGAAAGTGCGTTTGCT
    CCAGTCATGGAAGAATTAATCAAAAAGCTATCTGTAGCAGTTGATTGGTTTTCAAGTTTA
    AGTGATGGATCTAAAAGGTCGATTGTTATATTCGGTGGTATTGCTGCTGCAATTGGTCCT
    GTAGTTTTTGGATTAGGTGCATTCATAAGCACAGTTGGCAACGCAGTAACTGTATTAGCT
    CCATTATTAGCTAGTATTGCAAAGGCTGGTGGATTGATTAGTTTTTTATCGACTAAAGTA
    CCTATATTAGGAACTGTCTTCACAGCTTTAACTGGTCCAATTGGCATTGTATTAGGTGTA
    TTGGCTGGTTTAGCAGTCGCATTTACAATTGCTTATAAGAAATCTGAAACATTTAGAAAT
    TTTGTTAATGGTGCAATTGAAAGTGTTAAACAAACATTTAGTAATTTTATTCAATTTATT
    CAACCTTTCATTGATTCTGTTAAAAACATCTTTAAACAAGCGATATCAGCAATAGTTGAT
    TTTGCTAAAGATATTTGGAGTCAAATCAATGGATTCTTTAATGAAAATGGAATTTCCATT
    GTTCAAGCACTTCAAAATATATGCAACTTTATTAAAGCGATATTTGAATTTATTTTAAAT
    TTTGTAATTAAACCAATTATGTTCGCAATCTGGCAAGTGATGCAATTTATTTGGCCGGCG
    GTTAAAGCCTTGATTGTCAGCACTTGGGAAAATATCAAAGGTGTAATACAAGGGGCTATT
    AATATTATTTTGGGTATTATCAAAGTGTTCTCTAGTCTTTTCACAGGAAACTGGCGAGGC
    GTTTGGGACGGCATTGTAATGATACTGAAAGGTACTGTGCAGTTAATTTGGAATTTAATT
    CAATTATGGTTTGTAGGCAAAATACTTGGCGTTGTTAGGTACTTTGGCGGATTGCTAAAA
    GGTTTAATAACTATTATATGGGTTGCTATAATAGGCGTTTTCAAGAAATCATTATCGGCA
    ATTTGGAATGCAACAAAAAGTATTTTTGGTTTCTTATTCAATAGTGTTAAATCTATTTTC
    ACTAATATGAAAAACTGGTTATCTAGTACGTGGAATAATATCAAAAGCAATACCGTCGGC
    AAGGCTCATTCGTTATTTACGGGTGTAAGGTCTAAATTCACAAGTTTATGGAATGCGACG
    AAAGATATATTTATTAAATTAAGAAATTGGATGTCAAACATCTGGAACTCTATTAAAGAT
    AACACTGTAGGTATAGCTGGTCGCTTATGGGATAGAGTGCGTAACATCTTTGGAAGCATG
    CGTGACGGTTTAAAATCTATCATTGGTAAAATTAAAGATCATATCGGTGGTATGGTAGAC
    GCTGTTAAAAGAGGTCTTAATAAATTAATTGAAGGTTTAAACTGGGTCGGTGGTAAGTTG
    GGTATGGACAAAATACCGAAGTTACACACTGGTACTGAACATACGCATACTACTACAAGA
    TTAGTTAAGAACGGTAAGATTGCGCGGGATACGTTCGCTACGGTTGGGGATAAAGGACGT
    GGAAATGGTCCGAATGGTTTCAGAAATGAAATGATTGAATTCCCTAATGGCAAACGGGTA
    CTTACGCCTAATACAGATACGACAGCGTACTTACCTAAAGGTTCAAAAGTATATAACGGC
    GCACAAACTTATTCAATGTTAAATGGAACGCTTCCAAGATTTAGCATAGGTACTATGTGG
    AAAGATATTAAATCCGGTGCATCATCGGCATTTAACTGGACAAAAGATCAAATAGGTAAA
    GGTACCAAATGGCTTGGCGATAAAGTTGGCGATGTTTTAGATTTTATTGAAAATCCAGGC
    AAACTTTTAAATTATATACTTGAAGCTTTTGGAATTGATTTCAATTCTTTAACTAAAGGT
    ATGGGAATTGCAGGCGACATAACAAAAGCTGCATGGTCTAAGATTAAGAAAAGTGCTACT
    GATTGGATAAAAGAAAATTTAGAAGCTATGGGCGGTGGCGATTTAGTCGGCGGAATATTA
    GACCCTGACAAAATTAATTATCATTATGGACGTACCGCAGCTTATACCGCTGCAACTGGA
    AGACCATTTCATGAAGGTGTCGATTTTCCATTTGTATATCAAGAAGTTAGAACGCCGATG
    GGTGGCAGACTTACAAGAATGCCATTTATGTCTGGTGGTTATGGTAATTATGTAAAAATT
    ACTAGTGGCGTTATCGATATGCTATTTGCGCATTTGAAAAACTTTAGCAAATCACCACCT
    AGTGGCACGATGGTAAAGCCCGGTGATGTTGTTGGTTTAACTGGTAATACCGGATTTAGT
    ACAGGACCACATTTACATTTTGAAATGAGGAGAAATGGACGACATTTTGACCCTGAACCA
    TATTTAAGGAATGCTAAGAAAAAAGGAAGATTATCAATAGGTGGTGGCGGTGCTACTTCT
    GGAAGTGGCGCAACTTATGCCAGTCGAGTAATCCGACAAGCGCAAAGTATTTTAGGTGGT
    CGTTATAAAGGTAAGTGGATTCATGACCAAATGATGCGCGTTGCAAAACGTGAAAGTAAC
    TACCAGTCAAATGCAGTGAATAACTGGGATATAAATGCTCAAAGAGGAGACCCATCAAGA
    GGATTATTCCAAATCATCGGCTCAACTTTTAGAGCAAACGCTAAACGTGGATATACTAAC
    TTTAATAATCCGGTTCATCAAGGTATTTCAGCAATGCAGTACATTGTTAGACGCTACGGT
    TGGGATGGATTTAAGCGTGCGGGTGATTACGCATATGCTACAGGCGGAAAAGTTTTTGAT
    GGTTGGTATAACTTAGGTGAAGACGGTCATCCAGAATGGGTTATTCCAACAGATCCAGCT
    CGTAGAAATGATGCAATGAAGATGTTACATTATGCAGCTGCGGAAGTTAGAGGGAAAAAC
    GCAAGTAAGAATAAACGACCTAGTCAATTATCTAGTGTAAATGGGTTTGATGACCCAAGC
    TTATTATTGAAAATGATTGAACAACAGCAACAACAAATAGCTTTATTACTGAAGATAGCG
    CAATCTAACGATGTGATTGCAGATAAAGATTATCAGCCGATTATTGACGAATACGCTTTT
    GATAAAAAGGTGAACGCGTCTATAGAAAAGCGAGAAAGGCAAGAATCAACAAAAGTAAAG
    TTTAGAAAAGGAGGAATTGCTATTCAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4530

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA1766 [new locus tag: SA_RS10155 ]
  • symbol: SA1766
  • description: hypothetical protein
  • length: 1509
  • theoretical pI: 10.233
  • theoretical MW: 165436
  • GRAVY: -0.187939

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage tail tape measure protein, TP901 family, core region (TIGR01760; HMM-score: 61.8)
    and 11 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 23.8)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 23.8)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 23.8)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 23.8)
    two transmembrane protein (TIGR04527; HMM-score: 22.9)
    Unknown function Enzymes of unknown specificity quinoprotein relay system zinc metallohydrolase 2 (TIGR04559; EC 3.-.-.-; HMM-score: 13.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaD domain protein (TIGR01446; HMM-score: 12.6)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions DnaD domain protein (TIGR01446; HMM-score: 12.6)
    Genetic information processing Protein synthesis tRNA aminoacylation serine--tRNA ligase (TIGR00414; EC 6.1.1.11; HMM-score: 11.7)
    SH3 domain protein (TIGR04211; HMM-score: 8.1)
    helix-rich protein (TIGR04523; HMM-score: 1.9)
  • TheSEED  :
    • Phage tail, tail length tape-measure protein
    Phages, Prophages, Transposable elements, Plasmids Phages, Prophages Phage tail proteins 2  Phage tail length tape-measure protein
  • PFAM:
    no clan defined PhageMin_Tail; Phage-related minor tail protein (PF10145; HMM-score: 67.4)
    Hybrid (CL0105) Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 61.9)
    and 28 more
    Lysozyme (CL0037) SLT; Transglycosylase SLT domain (PF01464; HMM-score: 23.9)
    no clan defined DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 18.5)
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein (PF07926; HMM-score: 16.7)
    Goodbye; fungal STAND N-terminal Goodbye domain (PF17109; HMM-score: 15.3)
    EsxAB (CL0352) WXG100; Proteins of 100 residues with WXG (PF06013; HMM-score: 14.1)
    no clan defined TMP_2; Prophage tail length tape measure protein (PF06791; HMM-score: 13.5)
    EzrA; Septation ring formation regulator, EzrA (PF06160; HMM-score: 13.2)
    YtxH; YtxH-like protein (PF12732; HMM-score: 13.2)
    FapA; Flagellar Assembly Protein A (PF03961; HMM-score: 13.1)
    BCLiA (CL0551) APG6; Autophagy protein Apg6 (PF04111; HMM-score: 12.9)
    no clan defined DUF745; Protein of unknown function (DUF745) (PF05335; HMM-score: 12.4)
    YebO; YebO-like protein (PF13974; HMM-score: 12.3)
    TACC; Transforming acidic coiled-coil-containing protein (TACC) (PF05010; HMM-score: 12.1)
    TMPIT; TMPIT-like protein (PF07851; HMM-score: 11.5)
    Laminin_I; Laminin Domain I (PF06008; HMM-score: 11.4)
    GAS; Growth-arrest specific micro-tubule binding (PF13851; HMM-score: 11.3)
    HTH (CL0123) Mnd1; Mnd1 family (PF03962; HMM-score: 11.1)
    no clan defined Baculo_PEP_C; Baculovirus polyhedron envelope protein, PEP, C terminus (PF04513; HMM-score: 10.7)
    Spc24; Spc24 subunit of Ndc80 (PF08286; HMM-score: 10.1)
    BLOC1_2; Biogenesis of lysosome-related organelles complex-1 subunit 2 (PF10046; HMM-score: 9.9)
    DUF16; Protein of unknown function DUF16 (PF01519; HMM-score: 9.8)
    tRNA_bind_arm (CL0298) Seryl_tRNA_N; Seryl-tRNA synthetase N-terminal domain (PF02403; HMM-score: 9.7)
    no clan defined OmpH; Outer membrane protein (OmpH-like) (PF03938; HMM-score: 8.8)
    Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase (PF05929; HMM-score: 8.8)
    HeLo; Prion-inhibition and propagation (PF14479; HMM-score: 8)
    Carbpep_Y_N; Carboxypeptidase Y pro-peptide (PF05388; HMM-score: 7.5)
    Tho2; Transcription factor/nuclear export subunit protein 2 (PF11262; HMM-score: 6.5)
    DUF4407; Domain of unknown function (DUF4407) (PF14362; HMM-score: 6.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.35
    • Cellwall Score: 0.32
    • Extracellular Score: 0.32
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.020835
    • TAT(Tat/SPI): 0.002675
    • LIPO(Sec/SPII): 0.001517
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MGERIKGLSIGLDLDAANLNRSFAEIKRNFKTLNSDLKLTGNNFKYTEKSTHSYKQRIKELDGTITGYKKNVDDLAKQYGKVSQEQGENSAEAQKLRQEYNKQANELNFLEKELEKTTTEFEEFKKAQVEAQRMAESGWGKTSKVFESMGPKLTKMGDGLKSIGKGLMIGVTAPVLGIAAASGKAFAEVDKGLDTVTQATGATGGELKKLQNSFKDVYGNFPEDAETVGGVLGEVNTRLGFTGKELESATESFLKFSHITGSDGVQAVQLITRAMGDAGIEADEYQSVLDMVAKAAQASGISVDTLADSITKYGAPMRAMGFEMKESIALFSQWEKSGVNTEIAFSGLKKAISNWGKAGKDPREEFKKTLAEIERTPDIASATSLAIEAFGAKAGPDLADAIKGGRFSYQEFLKTIEDSQGTVNQTFKDSESGSERFKVAMNKLKLVGADVWASIESAFAPVMEELIKKLSVAVDWFSSLSDGSKRSIVIFGGIAAAIGPVVFGLGAFISTVGNAVTVLAPLLASIAKAGGLISFLSTKVPILGTVFTALTGPIGIVLGVLAGLAVAFTIAYKKSETFRNFVNGAIESVKQTFSNFIQFIQPFIDSVKNIFKQAISAIVDFAKDIWSQINGFFNENGISIVQALQNICNFIKAIFEFILNFVIKPIMFAIWQVMQFIWPAVKALIVSTWENIKGVIQGAINIILGIIKVFSSLFTGNWRGVWDGIVMILKGTVQLIWNLIQLWFVGKILGVVRYFGGLLKGLITIIWVAIIGVFKKSLSAIWNATKSIFGFLFNSVKSIFTNMKNWLSSTWNNIKSNTVGKAHSLFTGVRSKFTSLWNATKDIFIKLRNWMSNIWNSIKDNTVGIAGRLWDRVRNIFGSMRDGLKSIIGKIKDHIGGMVDAVKRGLNKLIEGLNWVGGKLGMDKIPKLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGRGNGPNGFRNEMIEFPNGKRVLTPNTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFSIGTMWKDIKSGASSAFNWTKDQIGKGTKWLGDKVGDVLDFIENPGKLLNYILEAFGIDFNSLTKGMGIAGDITKAAWSKIKKSATDWIKENLEAMGGGDLVGGILDPDKINYHYGRTAAYTAATGRPFHEGVDFPFVYQEVRTPMGGRLTRMPFMSGGYGNYVKITSGVIDMLFAHLKNFSKSPPSGTMVKPGDVVGLTGNTGFSTGPHLHFEMRRNGRHFDPEPYLRNAKKKGRLSIGGGGATSGSGATYASRVIRQAQSILGGRYKGKWIHDQMMRVAKRESNYQSNAVNNWDINAQRGDPSRGLFQIIGSTFRANAKRGYTNFNNPVHQGISAMQYIVRRYGWDGFKRAGDYAYATGGKVFDGWYNLGEDGHPEWVIPTDPARRNDAMKMLHYAAAEVRGKNASKNKRPSQLSSVNGFDDPSLLLKMIEQQQQQIALLLKIAQSNDVIADKDYQPIIDEYAFDKKVNASIEKRERQESTKVKFRKGGIAIQ

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]