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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1842 [new locus tag: SA_RS10570 ]
  • pan locus tag?: SAUPAN005275000
  • symbol: agrB
  • pan gene symbol?: agrB
  • synonym:
  • product: accessory gene regulator B

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1842 [new locus tag: SA_RS10570 ]
  • symbol: agrB
  • product: accessory gene regulator B
  • replicon: chromosome
  • strand: +
  • coordinates: 2079446..2080009
  • length: 564
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    TTGAATTATTTTGATAACAAAATTGACCAGTTTGCCACGTATCTTCAAAAGAGAAATAAC
    TTAGATCATATTCAATTTTTGCAAGTACGTTTAGGGATGCAAATTATAGTTGGTAATTTT
    TTTAAAATACTTGTAACATATAGTATTTCTATATTCTTAAGTGTATTTTTGTTTACCTTA
    GTTACACACTTATCCTATATGTTAATACGCTATAATGCACATGGTGCTCATGCAAAGTCT
    TCGATACTTTGTTACATACAAAGTATTTTAACATTTGTATTTGTACCTTATTTTCTAATT
    AATATAGACATTAATTTTACTTATTTACTGGCCTTATCTATTATAGGATTGATTTCCGTT
    GTTATTTATGCACCTGCAGCAACGAAAAAGCAACCTATACCAATAAAATTAGTAAAACGT
    AAAAAGTATTTATCTATAATTATGTATTTATTAGTTTTGATTCTATCCTTAATAATACAT
    CCATTTTATGCTCAATTTATGTTATTAGGAATTTTAGTGGAATCTATTACATTATTACCT
    ATTTTTTTCCCTAAGGAGGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    564

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1842 [new locus tag: SA_RS10570 ]
  • symbol: AgrB
  • description: accessory gene regulator B
  • length: 187
  • theoretical pI: 9.92193
  • theoretical MW: 21680
  • GRAVY: 0.845989

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.-.-?  ExPASy
  • TIGRFAM:
  • TheSEED  :
    • Accessory gene regulator B
  • PFAM:
    no clan defined AgrB; Accessory gene regulator B (PF04647; HMM-score: 110.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002038
    • TAT(Tat/SPI): 0.000082
    • LIPO(Sec/SPII): 0.015886
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: AgrA (activation) regulon, CodY (repression) regulon
    AgrA(TF)important in Virulence, Quorum sensing; RegPrecise 
    CodY(TF)important in Amino acid metabolism; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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