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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2230 [new locus tag: SA_RS12805 ]
  • pan locus tag?: SAUPAN005992000
  • symbol: SA2230
  • pan gene symbol?: flp
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2230 [new locus tag: SA_RS12805 ]
  • symbol: SA2230
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2503865..2505361
  • length: 1497
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGACTACTAAAAAACTGTATTTTCTATCCATTTCTATTATCATTTTAGTCGCCATTTCA
    ATTGCTATATATATAACATTAAATAGCAATACGAAGACACGGTTAACCAATGATTCGCAA
    CAACAAATAGATAAAATTATCGAGCATGATTTACAAAAGGGACACATTCCTGGAGCATCA
    ATTTTAATAGTAAAAAATGGCAAAGTTTTTTTAAATAAAGGTTATGGTTATCAAGATGTT
    GATAAAAAAGTCAAAGCTTCTCCCACAACAAAGTATGAAATTGCTTCTAATACTAAAGCT
    TTCACAGGTCTTGCAATTTTAAAATTAGCTCAAGAAGGTCGATTAAACTTAAATGATGAC
    GTATCCAAACATGTGCCTCATTTTAAAATGAACTATAATGGTCAAAATGAAACTATTACG
    ATTAAGCAACTTTTGGCTCAAACAAGTGGTATACCTAGTGATATTACAAGCGAAGACGCC
    GTAACAAATAAAAATAATCGTTTAAATGATGTAACCCGTGCAATTATGGGTGATGAATTA
    CATCATAAGCCCGGAGAAGAATTTGAATACTCAAATATGAACTATGATTTATTAGGTTTA
    ATTATCCAAAACGTTACGAAGCAATCCTATACAAAATATATTACAAATTCATGGCTCAAG
    CCTTTGCATATGACACATACATCATTCAAACAAACCAATAACAAATCAAAACATGATGCT
    ATTGGCTACGAATTACAAGGTTCGACACCTGTCGTCTCTAAACCTGAATTTAACCTTTGG
    GATACACCATCAGCATATATGATGACATCAACTGAAGATTTGGAACATTGGATAAAATTC
    CAACTTAATCCACCTGATAAATACAAATCATTAGTTCAACAATCACATAAAAATTTATCA
    TCAACAATTGGTGAACCTAATGCCAATGCATATGCTTCGGGCTGGTTTACCAATAATGAT
    GAACATTTAGTGTTTCATTCAGGAACGCTCGATAACTTTTCATCATTTATTTTACTAAAT
    CCAAAACAAAATTATGGAATTGTTGTGCTTGCAAATCTAAATTCGGAATATGTACCCAAA
    TTAGTTGAGCATCTTAATACACAAATTGTAAATCACAAGCGATATTCGACGGTTGCGTCT
    ATACTCAATCAATATAAAGACCAATTTAATATTGTTACCGTTTTGATGACAACACTTATT
    TTATTAGCATTTATATTCTCAGCTTATCGTGCTTGGCAAATGCGCCATGGTCAAATTCTT
    TTGCGTAGATCAAAACGGATTGCTGTATTGAGTTGGCTAACTTTATGTTTATGTATCGCT
    ATAGCGCTCATATTATATGCATTACCATATCTCATTCTCGGTAGCAATAATTGGTCTTTT
    GTACTGACTTGGCTACCAATAGAAATTAAATTAGCACTAATCACAACATTAATTGCATTA
    TTCAGTACATTAATTGTAATTCTGTTATTCCTTCATACAAAGATAACGAAGACATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1497

Protein[edit | edit source]

Protein Data Bank: 4GDN

General[edit | edit source]

  • locus tag: SA2230 [new locus tag: SA_RS12805 ]
  • symbol: SA2230
  • description: hypothetical protein
  • length: 498
  • theoretical pI: 9.66296
  • theoretical MW: 56495.9
  • GRAVY: -0.0909639

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 8.5)
  • TheSEED:  
    Phages, Prophages, Transposable elements, Plasmids Transposable elements Tn552  Beta-lactamase (EC 3.5.2.6)
    and 1 more
    Virulence, Disease and Defense Resistance to antibiotics and toxic compounds Beta-lactamase  Beta-lactamase (EC 3.5.2.6)
  • PFAM:
    Beta-lactamase (CL0013) Beta-lactamase; Beta-lactamase (PF00144; HMM-score: 240.4)
    and 2 more
    GPCR_A (CL0192) 7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR (PF00003; HMM-score: 16.3)
    no clan defined SIT; SHP2-interacting transmembrane adaptor protein, SIT (PF15330; HMM-score: 10.8)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.449986
    • TAT(Tat/SPI): 0.001717
    • LIPO(Sec/SPII): 0.091224
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDKIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKAFTGLAILKLAQEGRLNLNDDVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDAVTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKHDAIGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDEHLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASILNQYKDQFNIVTVLMTTLILLAFIFSAYRAWQMRHGQILLRRSKRIAVLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLALITTLIALFSTLIVILLFLHTKITKT

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

  • SA2230 no polycistronic organisation predicted

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]