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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL0046 [new locus tag: SACOL_RS00245 ]
- pan locus tag?: SAUPAN000509000
- symbol: SACOL0046
- pan gene symbol?: —
- synonym:
- product: metallo-beta-lactamase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL0046 [new locus tag: SACOL_RS00245 ]
- symbol: SACOL0046
- product: metallo-beta-lactamase
- replicon: chromosome
- strand: -
- coordinates: 53428..54756
- length: 1329
- essential: unknown
⊟Accession numbers[edit | edit source]
- Gene ID: 3236998 NCBI
- RefSeq: YP_184956 NCBI
- BioCyc: see SACOL_RS00245
- MicrobesOnline: 911530 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1321ATGTTTTTTAAACAATTTTATGATAAACATTTATCTCAAGCATCTTATTTAATCGGTTGT
CAAAAAACTGGAGAAGCCATGATTATTGATCCTATTCGTGACTTATCTTCATATATTCGA
GTTGCTGATGAAGAAGGTTTAACCATTACTCATGCAGCTGAAACACATATACATGCAGAT
TTTGCTTCAGGAATTAGAGATGTTGCTATAAAGTTAAATGCTAATATTTATGTATCGGGT
GAAAGTGATGACACATTAGGTTATAAAAATATGCCTAACCACACTCATTTTGTTCAACAT
AATGACGATATTTATGTAGGAAATATAAAATTAAAAGTGCTTCATACACCGGGTCACACG
CCAGAAAGTATAAGTTTTTTACTTACTGACGAAGGTGCTGGAGCACAAGTTCCAATGGGA
CTATTCAGTGGTGATTTTATTTTTGTAGGAGATATCGGTAGACCTGATTTACTAGAAAAA
GCGGTTAAAGTAGAAGGATCATCTGAAATAGGCGCTAAACAAATGTTTAAATCGATTGAA
AGTATTAAAGACTTGCCAGATTACATTCAAATTTGGCCTGGCCATGGCGCTGGTAGTCCT
TGTGGTAAATCTTTAGGTGCTATTCCAACATCTACTCTTGGCTATGAAAAACAAACGAAC
TGGGCTTTTTCTGAAAATAACGAAGCTACCTTTATCGATAAACTCATTTCTGACCAACCT
GCACCACCACATCATTTTGCACAAATGAAAAAAATTAATCAATTCGGTATGAATTTATAT
CAACCTTATACGGTTTATCCAGCTACAAATACAAACAGATTAACTTTTGATCTCCGCAGT
AAGGAGGCTTATCATGGTGGACATATTGAAGGTACAATCAATATTCCATATGATAAAAAT
TTCATCAATCAAATTGGCTGGTATCTAAACTATGATCAAGAAATTAACTTGATTGGAGAC
TATCACCTTGTTTCAAAAGCAACACACACCTTACAACTCATTGGATACGATGATATTGCT
GGATATCAATTACCGCAATCTAAGATTCAAACACGTTCCATTCATAGTGAAGACATTACA
GGTAACGAATCACATATATTAGATGTACGTAATGATAATGAATGGAATAATGGCCACTTA
TCTCAAGCGGTTCATGTACCACACGGCAAACTTTTAGAAACAGATTTACCTTTCAATAAA
AACGATGTTATTTATGTACACTGTCAGTCTGGCATTAGAAGTTCGATAGCTATTGGTATT
TTAGAACACAAAGGTTATCACAACATTATTAATGTAAATGAAGGTTATAAAGATATACAA
CTTTCTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL0046 [new locus tag: SACOL_RS00245 ]
- symbol: SACOL0046
- description: metallo-beta-lactamase
- length: 442
- theoretical pI: 5.97736
- theoretical MW: 49410
- GRAVY: -0.387104
⊟Function[edit | edit source]
- ⊞TIGRFAM: Cellular processes Detoxification hydroxyacylglutathione hydrolase (TIGR03413; EC 3.1.2.6; HMM-score: 74.5)and 3 more
- TheSEED :
- Polysulfide binding protein
- Zn-dependent hydroxyacylglutathione hydrolase
- ⊞PFAM: Phosphatase (CL0031) Rhodanese; Rhodanese-like domain (PF00581; HMM-score: 66.3)and 1 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MFFKQFYDKHLSQASYLIGCQKTGEAMIIDPIRDLSSYIRVADEEGLTITHAAETHIHADFASGIRDVAIKLNANIYVSGESDDTLGYKNMPNHTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVEGSSEIGAKQMFKSIESIKDLPDYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVYPATNTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYDQEINLIGDYHLVSKATHTLQLIGYDDIAGYQLPQSKIQTRSIHSEDITGNESHILDVRNDNEWNNGHLSQAVHVPHGKLLETDLPFNKNDVIYVHCQSGIRSSIAIGILEHKGYHNIINVNEGYKDIQLS
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization: Lipoprotein [1]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)