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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • pan locus tag?: SAUPAN001168000
  • symbol: SACOL0267
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • symbol: SACOL0267
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 305492..307015
  • length: 1524
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGTCTAAAAAGTTAAAAATTATAATTCCTATTATTATTGTCTTACTATTAATAGGTGGA
    ATCGCATGGGGAGTTTATGCATTTTTTGCTAATACACCGAAAAATACATACCTAAAAAGT
    GAACAACAAACAGCAAAAATGTATAAAGATTATTTTAATGACCGTTTTGAAAATGAAGTG
    AAGTTCCAAGAAAAGATGAAAGATAATTCGTTTTTATCTTCATTAGAATTAAGCGCAGAT
    GCATCAGATGAAATTGTTAAAGGGCTTGGCATTCCTAAATCTGTTGTTAATGCATCGAAA
    ATTAAAATGTCATATGGACATGATCCTAAAAAAGAGAAATCAATGATTAATCTTGAACCA
    ACAATCGCAGACTCTGCATTAGGGAAATTCCAGTTAGCTGCAGATAAAGATAAGCATTAT
    TTCGAATCACCATTATTTAAAGGGAAATATAGTGTTAATAATTCTGATTTATTATCAACT
    TATTCAAAACTTACAGGTGAAGATGAAGAAACAGCAAAAGAAAATGGTATTACAAACCAA
    CAACTAAATTTAAATACTCTTTTTAATAATGCTCAAGCACAACAAAGTGACTACAGCAAA
    ATTGCCGAAAAATATTCCGAACTTATTGTCGACAAATTAGATGACGATAATTTTGATAAA
    GGTAAAAAAGAAGAAATTAAGGTTAATGGTGAAAAGTACAAAGTTAGACCTGTCACGTTA
    ACACTTAGCAGAGCTGACACTAAAAAAATTACATTAGCTGTATTAGAAGAAGCTAAAAAG
    GATAAAGACCTTAAAAAATTAATGGAAGAACAAGGTGCTAGAAAAGACTTTGAAAAAGAC
    ATCAAAAAAGCAATTGACGATGTCAAAGAAACTAAAAAGGATGAATTTGCTAAAATTCAA
    TCTAAAATTTATACCGAAAAACATACGATTGTAAAACGAGAAATTACTATTACAGACAAA
    GAAAATAATAAAACTAAAATCAAAGGTACTAATACTTTAGAAGACGATAAGTTAAAACTA
    GATTACGCACTTGATTTCGATCAAGATAAATACACGTATGCTGAAGCGAAATATACAATT
    AAAGGCGTATCTTCTAAAGAAAAAGATAATAAATATAATGATAAATACGAATTTGGTAAA
    AAGACAGAATATGATGAATCAAAAATCAAATTAGATAACCAAGAAAAAGTAGATGGCACA
    AAACGTCAAGATAAAGGTAAAATCACTGTCGCATTAGATAAATATAGCGACGAAAATGAA
    TTCACTTTTGAAAATAATATAGATTCTGACGTAAAAAATAACACTCAGAAATCTACGTTA
    AATATCGGCATCAAATATGCTGAAGAACCAATTAATTTCATTTTAAAATCTAGCACAAAA
    TTGAAAGCAGATATTGATTTTGATGATAGTGGTGCAAAAGATTTCAATAGTCTATCTTCA
    AAAGACCGTGAAAAACTTGAAAAAGAAATCGAAAAAAATGGCGGCAAAATGTTTGAATCA
    ATTTTAAAAAAGGCATCTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1524

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL0267 [new locus tag: SACOL_RS01355 ]
  • symbol: SACOL0267
  • description: hypothetical protein
  • length: 507
  • theoretical pI: 8.69108
  • theoretical MW: 57977.1
  • GRAVY: -0.905917

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01108182: hypothetical protein
  • PFAM:
    BRCT-like (CL0459) PTCB-BRCT; twin BRCT domain (PF12738; HMM-score: 12.8)
    no clan defined Orthopox_F14; Orthopoxvirus F14 protein (PF06076; HMM-score: 12.5)
    and 3 more
    SapC; SapC (PF07277; HMM-score: 9.9)
    DUF378; Domain of unknown function (DUF378) (PF04070; HMM-score: 9.4)
    DUF2746; Protein of unknown function (DUF2746) (PF10874; HMM-score: 9.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: 4
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.703659
    • TAT(Tat/SPI): 0.002845
    • LIPO(Sec/SPII): 0.022967
    • Cleavage Site: CS pos: 27-28. VYA-FF. Pr: 0.4302
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKKLKIIIPIIIVLLLIGGIAWGVYAFFANTPKNTYLKSEQQTAKMYKDYFNDRFENEVKFQEKMKDNSFLSSLELSADASDEIVKGLGIPKSVVNASKIKMSYGHDPKKEKSMINLEPTIADSALGKFQLAADKDKHYFESPLFKGKYSVNNSDLLSTYSKLTGEDEETAKENGITNQQLNLNTLFNNAQAQQSDYSKIAEKYSELIVDKLDDDNFDKGKKEEIKVNGEKYKVRPVTLTLSRADTKKITLAVLEEAKKDKDLKKLMEEQGARKDFEKDIKKAIDDVKETKKDEFAKIQSKIYTEKHTIVKREITITDKENNKTKIKGTNTLEDDKLKLDYALDFDQDKYTYAEAKYTIKGVSSKEKDNKYNDKYEFGKKTEYDESKIKLDNQEKVDGTKRQDKGKITVALDKYSDENEFTFENNIDSDVKNNTQKSTLNIGIKYAEEPINFILKSSTKLKADIDFDDSGAKDFNSLSSKDREKLEKEIEKNGGKMFESILKKASK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Signal peptide containing [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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