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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1706 [new locus tag: SACOL_RS08710 ]
  • pan locus tag?: SAUPAN004260000
  • symbol: SACOL1706
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1706 [new locus tag: SACOL_RS08710 ]
  • symbol: SACOL1706
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1736340..1736624
  • length: 285
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    GTGACTCTATTTATTATTATCGGGGTTCTCGTGCCAATGGTTTATACCATGCAGTTAAAT
    ATTAAAAATGAACCTGTAACAAAGCGCAATCTTTTAATAACATTAGCTTTATCTACGTTA
    GGTATTTTAGTAACCGCGTTAGCAGGTGTAATCGTTACGAAACAAGCTTTTCCTTTATTA
    AGTGTAGCAATTGGCTCAATTTTTACTGGAATCGTTTGGGGCCTTTTACTAAGTGGTAGC
    TACGCGCTGATACGATTTTTATCTAACGCATTTGGGCGTAAGTAA
    60
    120
    180
    240
    285

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL1706 [new locus tag: SACOL_RS08710 ]
  • symbol: SACOL1706
  • description: hypothetical protein
  • length: 94
  • theoretical pI: 11.2593
  • theoretical MW: 10120.3
  • GRAVY: 1.15638

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01108281: hypothetical protein
  • PFAM:
    no clan defined DUF1705; Domain of unknown function (DUF1705) (PF08019; HMM-score: 13.2)
    and 3 more
    DUF5467; Family of unknown function (DUF5467) (PF17555; HMM-score: 9.3)
    GT-C (CL0111) YfhO; Bacterial membrane protein YfhO (PF09586; HMM-score: 8.2)
    no clan defined DUF3481; C-terminal domain of neuropilin glycoprotein (PF11980; HMM-score: 7.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.025897
    • TAT(Tat/SPI): 0.001093
    • LIPO(Sec/SPII): 0.028258
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTLFIIIGVLVPMVYTMQLNIKNEPVTKRNLLITLALSTLGILVTALAGVIVTKQAFPLLSVAIGSIFTGIVWGLLLSGSYALIRFLSNAFGRK

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Integral membrane [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit | edit source]