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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2082 [new locus tag: SACOL_RS10895 ]
  • pan locus tag?: SAUPAN005371000
  • symbol: SACOL2082
  • pan gene symbol?: yidC
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2082 [new locus tag: SACOL_RS10895 ]
  • symbol: SACOL2082
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2147624..2148496
  • length: 873
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAGAAAAAAGCGTTACTACCATTATTTTTAGGTATTATGGTCTTTTTGGCTGGTTGT
    GACTATTCTAAACCTGAAAAACGTAGTGGGTTTTTCTACAATACATTCGTAGATCCAATG
    AAAAATGTATTGGATTGGTTGGGAAATAACTTATTAAACGACAATTATGGTTTAGCTATT
    ATTATCCTTGTATTGGTAATTCGTATTATTTTATTACCATTCATGTTGTCAAACTATAAA
    AATAGTCATATGATGCGTCAAAAAATGAAAGTTGCAAAGCCAGAAGTTGAAAAAATTCAA
    GAAAAAGTGAAACGTGCGCGTACACAAGAAGAAAAAATGGCTGCAAACCAAGAATTAATG
    CAAGTATATAAAAAGTATGACATGAACCCGATTAAGAGTATGTTGGGTTGTTTACCAATG
    CTAATCCAATTACCAATCATCATGGGATTATACTTTGTACTTAAAGACCAACTTGTAGAT
    GGTTTGTTTAAATATCCACACTTCTTATGGTTCGATTTAGGACGTCCTGATATTTGGATT
    ACAATTATTGCCGGTGTTTTATACTTTATCCAAGCATATGTATCAAGTAAAACGATGCCA
    GACGAACAACGTCAAATGGGTTACATGATGATGGTCATTTCACCAATTATGATTATCTGG
    ATTTCATTAAGCTCAGCATCAGCACTTGGTTTGTACTGGTCAGTCAGTGCGGCGTTCCTT
    GTAGTTCAAACACACTTTGCGAACATTTATTATGAAAAAGTCGCTAAAAAAGAAGTACAA
    CCTTTCATTGAAGCGTATGAAAGAGAGCACAACGGCGGCAGCAATAAAAAAGGCAAAAAC
    ACACAAGTTGTGTCTAAAAAGAAAAAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2082 [new locus tag: SACOL_RS10895 ]
  • symbol: SACOL2082
  • description: hypothetical protein
  • length: 290
  • theoretical pI: 10.1207
  • theoretical MW: 33580.9
  • GRAVY: 0.0365517

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking membrane protein insertase, YidC/Oxa1 family (TIGR03592; HMM-score: 160.7)
  • TheSEED  :
    • Inner membrane protein translocase and chaperone YidC, short form OxaI-like
    Cell Division Subsystem including YidCD  Inner membrane protein translocase component YidC, short form OxaI-like
  • PFAM:
    Oxa1 (CL0376) 60KD_IMP; 60Kd inner membrane protein (PF02096; HMM-score: 151.5)
    and 9 more
    no clan defined EI24; Etoposide-induced protein 2.4 (EI24) (PF07264; HMM-score: 20.2)
    DUF4181; Domain of unknown function (DUF4181) (PF13789; HMM-score: 13.9)
    Succ_DH_flav_C; Fumarate reductase flavoprotein C-term (PF02910; HMM-score: 13.8)
    MLANA; Protein melan-A (PF14991; HMM-score: 13.8)
    MFS (CL0015) OATP; Organic Anion Transporter Polypeptide (OATP) family (PF03137; HMM-score: 11.6)
    no clan defined DUF4446; Protein of unknown function (DUF4446) (PF14584; HMM-score: 11.5)
    Trigger_C (CL0262) SurA_N_2; SurA N-terminal domain (PF13623; HMM-score: 10.7)
    Hypoth_1 (CL0447) DUF3784; Domain of unknown function (DUF3784) (PF12650; HMM-score: 8.9)
    no clan defined DUF5325; Family of unknown function (DUF5325) (PF17259; HMM-score: 8.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane(Lipid modified N-termini)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPII)
    • Intracellular possibility: 0
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: VFLAGCD
  • SignalP: Signal peptide LIPO(Sec/SPII) length 19 aa
    • SP(Sec/SPI): 0.000365
    • TAT(Tat/SPI): 0.000066
    • LIPO(Sec/SPII): 0.999252
    • Cleavage Site: CS pos: 19-20. LAG-CD. Pr: 0.9999
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVDGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNKKGKNTQVVSKKKKK

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Lipoprotein [1] [2]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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