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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
- pan locus tag?: SAUPAN006110000
- symbol: sarU
- pan gene symbol?: sarU
- synonym:
- product: accessory regulator U
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
- symbol: sarU
- product: accessory regulator U
- replicon: chromosome
- strand: +
- coordinates: 2563936..2564679
- length: 744
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3238097 NCBI
- RefSeq: YP_187302 NCBI
- BioCyc: see SACOL_RS13140
- MicrobesOnline: 913980 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721GTGGACTATCAAACTTTCGAAAAGGTCAATAAATTCATAAATGTAAAAGCGTACATATTT
TTTCTCACTCAAGAGTTAAAGCAACAATATAAATTATCATTAAAAGAATTGTTGATATTA
GCATATTTTTATTACAAAAATGAACACAGTATTTCACTAAAAGAAATCATTGGTGACATA
CTTTACAAACAATCTGATGTTGTAAAGAACATTAAGTCACTATCTAAAAAAGGATTTATA
AATAAGTCTAGAAACGAAGCAGATGAACGCCGTATTTTTGTTTCAGTTACTCCAATACAA
CGTAAAAAGATTGCTTGTGTTATTAATGAGTTAGATAAAATAATTAAAGGATTTAATAAG
GAAAGAGACTACATAAAATATCAATGGGCTCCAAAATATAGCAAAGAATTTTTTATACTT
TTTATGAACATTATGTACTCAAAAGATTTTTTAAAATATCGATTTAATTTAACATTTCTT
GATTTATCTATCTTATATGTAATATCATCTCGAAAAAATGAGATACTAAATTTAAAAGAT
TTGTTTGAAAGTATTAGATTTATGTATCCTCAAATTGTTAGGTCAGTTAATAGATTAAAT
AATAAAGGTATGCTAATCAAAGAACGATCCCTTGCAGATGAAAGGATTGTGTTAATCAAA
ATAAATAAAATACAATATAACACTATTAAAAGCATATTCACAGATACTTCCAAGATTCTC
AAACCAAGAAAATTTTTCTTTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
- symbol: SarU
- description: accessory regulator U
- length: 247
- theoretical pI: 10.4105
- theoretical MW: 29792
- GRAVY: -0.246964
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 209.5)and 1 morehomoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 35.4)
- TheSEED :
- Transcriptional regulator SarU (Staphylococcal accessory regulator U)
- PFAM: HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 36.3)HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 34.9)MarR_2; MarR family (PF12802; HMM-score: 29.8)and 4 moreTrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 19.2)Rrf2; Transcriptional regulator (PF02082; HMM-score: 14.3)HTH_Tnp_4; Helix-turn-helix of DDE superfamily endonuclease (PF13613; HMM-score: 14.1)OB (CL0021) CSD; 'Cold-shock' DNA-binding domain (PF00313; HMM-score: 12.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.67
- Cytoplasmic Membrane Score: 0.01
- Cellwall Score: 0.15
- Extracellular Score: 0.17
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002607
- TAT(Tat/SPI): 0.000108
- LIPO(Sec/SPII): 0.000474
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MDYQTFEKVNKFINVKAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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