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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
  • pan locus tag?: SAUPAN006110000
  • symbol: sarU
  • pan gene symbol?: sarU
  • synonym:
  • product: accessory regulator U

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
  • symbol: sarU
  • product: accessory regulator U
  • replicon: chromosome
  • strand: +
  • coordinates: 2563936..2564679
  • length: 744
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    GTGGACTATCAAACTTTCGAAAAGGTCAATAAATTCATAAATGTAAAAGCGTACATATTT
    TTTCTCACTCAAGAGTTAAAGCAACAATATAAATTATCATTAAAAGAATTGTTGATATTA
    GCATATTTTTATTACAAAAATGAACACAGTATTTCACTAAAAGAAATCATTGGTGACATA
    CTTTACAAACAATCTGATGTTGTAAAGAACATTAAGTCACTATCTAAAAAAGGATTTATA
    AATAAGTCTAGAAACGAAGCAGATGAACGCCGTATTTTTGTTTCAGTTACTCCAATACAA
    CGTAAAAAGATTGCTTGTGTTATTAATGAGTTAGATAAAATAATTAAAGGATTTAATAAG
    GAAAGAGACTACATAAAATATCAATGGGCTCCAAAATATAGCAAAGAATTTTTTATACTT
    TTTATGAACATTATGTACTCAAAAGATTTTTTAAAATATCGATTTAATTTAACATTTCTT
    GATTTATCTATCTTATATGTAATATCATCTCGAAAAAATGAGATACTAAATTTAAAAGAT
    TTGTTTGAAAGTATTAGATTTATGTATCCTCAAATTGTTAGGTCAGTTAATAGATTAAAT
    AATAAAGGTATGCTAATCAAAGAACGATCCCTTGCAGATGAAAGGATTGTGTTAATCAAA
    ATAAATAAAATACAATATAACACTATTAAAAGCATATTCACAGATACTTCCAAGATTCTC
    AAACCAAGAAAATTTTTCTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    744

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2507 [new locus tag: SACOL_RS13140 ]
  • symbol: SarU
  • description: accessory regulator U
  • length: 247
  • theoretical pI: 10.4105
  • theoretical MW: 29792
  • GRAVY: -0.246964

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 209.5)
    and 1 more
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 35.4)
  • TheSEED  :
    • Transcriptional regulator SarU (Staphylococcal accessory regulator U)
  • PFAM:
    HTH (CL0123) Staph_reg_Sar_Rot; Transcriptional regulator SarA/Rot (PF22381; HMM-score: 115.7)
    and 8 more
    HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 42.2)
    MarR_2; MarR family (PF12802; HMM-score: 40)
    MarR; MarR family (PF01047; HMM-score: 36.4)
    DnaD_N; DnaD N-terminal domain (PF21984; HMM-score: 19.7)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 17.7)
    F-93_WHD; F-93, winged-helix domain (PF22194; HMM-score: 14.8)
    HTH_Tnp_4; Helix-turn-helix of DDE superfamily endonuclease (PF13613; HMM-score: 13.4)
    WHD_MCM8; MCM8 winged helix domain (PF25051; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7247
    • Cytoplasmic Membrane Score: 0.1273
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.1473
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002607
    • TAT(Tat/SPI): 0.000108
    • LIPO(Sec/SPII): 0.000474
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDYQTFEKVNKFINVKAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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