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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2546 [new locus tag: SACOL_RS13330 ]
  • pan locus tag?: SAUPAN006185000
  • symbol: SACOL2546
  • pan gene symbol?: —
  • synonym:
  • product: perfringolysin O regulator protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2546 [new locus tag: SACOL_RS13330 ]
  • symbol: SACOL2546
  • product: perfringolysin O regulator protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2603696..2604739
  • length: 1044
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGATATTCTGTTAGGTGTAGGCACATTAGTCTTGGTTTTAGTGATCATGACGCTATTT
    TTAAAGTATGCACCGTACGGTAAACAAGGACTACAAGCATTATCCGGTGCAGCTTGTGCG
    ACATTTCTACCACAAGCATTCTTAAGTTATGCTATTGGTGGCGTATTTGATATTAAATTT
    CTACAAGATATTGGGGATTTAGCAGGAAGTTTAAGCGGTATCGCAGTAGGTATTCTAACG
    TGCTTAAACTTAGGCGTTGCACCAGTATTTGCGGTCATTGTTGGTTTAGTATTACATGAC
    TTTAAATTATTACCAGCATTCATCGCAGCTTATGGCGTAGCTTTTTTAATTAAATGGATT
    GAAAAGAAAGTTCCAGAAGGCTTGGACTTAATTGTGGTGATCTTATTTGCACCAGCAATT
    GCTTTCGGACTTGCATCAATCATTACACCTGGTGTGCTAGCAACATTAAAACAAATAGGT
    AGTGCTGTCACTGCGGTAGGTGATAACAATCCATATGCATTAGCGGTCATTTTAGGACTA
    GTGATTCCTGTTACAGGTATGACACCGCTAAGTTCAATGGTATTAACAAGTTTATTAGGA
    CTGACAGGTGTTCCTATGGCTATTGGAGCACTAACATGTACAGGTAGCTCATTTGTTAAC
    CTTATTTTATTCCGAAAATTAAACATTGGTGGACCGTCAAAAGCATTTGCAGTTTGTATT
    GAGCCATTGACGCAAATTGATTTAATAGCGCAATATCCAGTACAACTATATGGTACAAAT
    GCACTGATTGGGGTCGTCAACGCATGTATCGTGACATTTAGCGGACTAGTAATAGGTGTC
    AAAGGTATGGCAACACCAATTGCAGGCGCCATCGTATTGTTTGGCTTTAATAATGCAGTG
    ACATCAATTGTAACAATCGCAACAGTGATTATTGTCAGCATTGTCTTAGCCTATATTATT
    GGAACACTAATTAATAAGTTTAATTTAATGAATATCAACTTTAAAATGCCGAGCAAAAAG
    AATCATATTAAGGAGAGTGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1044

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2546 [new locus tag: SACOL_RS13330 ]
  • symbol: SACOL2546
  • description: perfringolysin O regulator protein
  • length: 347
  • theoretical pI: 8.92098
  • theoretical MW: 36034.3
  • GRAVY: 1.15793

⊟Function[edit | edit source]

  • TIGRFAM:
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 16.3)
  • TheSEED  :
    • Transcriptional regulator pfoR
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC_2; Phosphotransferase system, EIIC (PF13303; HMM-score: 142.7)
    and 1 more
    PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 16.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP: Multi-transmembrane(Lipid modified N-termini)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPII)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: AVGILTC
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.102909
    • TAT(Tat/SPI): 0.00226
    • LIPO(Sec/SPII): 0.007283
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDILLGVGTLVLVLVIMTLFLKYAPYGKQGLQALSGAACATFLPQAFLSYAIGGVFDIKFLQDIGDLAGSLSGIAVGILTCLNLGVAPVFAVIVGLVLHDFKLLPAFIAAYGVAFLIKWIEKKVPEGLDLIVVILFAPAIAFGLASIITPGVLATLKQIGSAVTAVGDNNPYALAVILGLVIPVTGMTPLSSMVLTSLLGLTGVPMAIGALTCTGSSFVNLILFRKLNIGGPSKAFAVCIEPLTQIDLIAQYPVQLYGTNALIGVVNACIVTFSGLVIGVKGMATPIAGAIVLFGFNNAVTSIVTIATVIIVSIVLAYIIGTLINKFNLMNINFKMPSKKNHIKESV

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Carbon catabolism; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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