From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS13105 [old locus tag: SACOL2501 ]
  • pan locus tag?: SAUPAN006091000
  • symbol: SACOL_RS13105
  • pan gene symbol?: pgcA
  • synonym:
  • product: phosphoglucomutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS13105 [old locus tag: SACOL2501 ]
  • symbol: SACOL_RS13105
  • product: phosphoglucomutase
  • replicon: chromosome
  • strand: +
  • coordinates: 2554511..2556319
  • length: 1809
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2554511..2556319) NCBI
  • BioCyc: SACOL_RS13105 BioCyc
  • MicrobesOnline: see SACOL2501

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGCATTTTCATACACATCTATTATATAATACTTGTGAAAAGTATTGTCTTGGGGCTGTG
    TTTTTTTACTTTTGGGGCGTATTTCTTTATAATTCATTACATAAATGTAAGGGCTTTAGT
    TTTCATGTTTTATTAAGTCTAACTGAGATTTTGAAAGGATGTTTAGCAACAATGGATAAA
    GAATTATGGATAGAACGAGCTAATGATAGTTTAGTTAAACATTTTTATGAGCAGCAATCT
    GACATTGAACAGCGAGAAGGTTTTGAAAGTAAATTAACATTTGGTACTGCGGGTATACGC
    GGAAAATTCGGTCTTGGTGAAGGTCGACTTAATAAGTTTACTATTGAAAAATTGGCATTA
    GGTTTAGCGCGTTATTTAAATGCCCAAACAAACAGTCCAACAATAGTCATTCATTATGAT
    ATTAGACATCTTTCAACTGAATTCGCCCAAATAATTGCTAATGTATTAGCAAACCATCAA
    ATAACAGTTTATTTACCTGATACATATAAAACGACACCGGAATTATCGTTCGCGGTGCGC
    AATCTTAATACTACTGCTGGCATTATGATTACAGCAAGTCATAATCCGAAAGACTATAAC
    GGCATCAAAGTATATGGTTCTGATGGTGCGCAATTATCGACTGATGCATCTGAGCTTGCA
    AGTCGTTATATCGAAGAAGTTGGCGATCCATTACAGATTGATATACCTATTTCTAAACAA
    AATACATCTTATATCAAGCCTTTTCCGAAATCTGTAACTGATGACTATATGAAACACATT
    CAAAATATGATTGGCTATATTCCTAAATCTGATTTACAAGTTGTGTTCACTAGTTTGCAT
    GGTACAAGTGTTCCGATTGTACCTGAGTTATTACAATCTTTGAATTTCAATCAATTTAAT
    CTTGTAGAAGCACAATGTAAACCTGATCCGAATTTCAGCTCAGTTCAAAGTGCTAATCCT
    GAAGATCATCGCGCTTTTGATCAAGCAGTCGAACTTGCAAATAAAAGTCATGCAGACTTA
    TTAATATCAACTGACCCTGATGCAGATCGACTTGGTATTGCTGAACGTGATGCACACGGT
    CATATCACATATTTTAATGGCAACCAAATTGGTGCGCTGTTACTTAATTATCGTATTCAA
    CAAACGTCTCAATTACGTCACCGCTTAATGATTCAATCTATTGTAAGTAGTGAGTTAACA
    AAGTCATTAGCACGCTATAATAATGTTGAATACAAAGAGGTGCTGACGGGCTTTAAATTT
    ATTGCTCAGGAAATAAGACAACTGGATGATCATCAAAATATGATTTTCGCATTTGAAGAG
    AGTTACGGTTTTCTATCAGAGCCTTTTGTACGTGATAAAGATGCCGTACAAATTGTGCCA
    CTCATTATAAAATACGCTTCTGAGTTAAAATTATATGGCAAAACATTGAAAGATGAATTA
    GAACAGATTTATCAAACTGTTGGTAGACATGAGGATACATTATTCTCGCATACGCTAGAA
    GGATTTGAAGGGAAAAAGAAAATTAATGCAATAATGACCAAATTCCGTTCAAATCCACCG
    CAAGAGATTCAAGGACTCAAAGTGAAAGCAATTGAAGATTATTTAACTAGCGAGGTTTAT
    CATTTGGATAAAGATACAACGTCGCAGATTAATTCTCCTAAATCAAATGTTATTCGTGTC
    TTATTTGACGAAGGATTTATCGCTTTACGTCCTTCTGGTACTGAACCTAAAATTAAATTA
    TATGTGTCGTTAAAATGTCCGAATTTTGATGATGTAGCTCAAAAAATTAATGCGATGATT
    TTTAGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1809

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS13105 [old locus tag: SACOL2501 ]
  • symbol: SACOL_RS13105
  • description: phosphoglucomutase
  • length: 602
  • theoretical pI: 6.55157
  • theoretical MW: 68347.3
  • GRAVY: -0.275581

⊟Function[edit | edit source]

  • reaction:
    EC 5.4.2.2?  ExPASy
    Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
  • TIGRFAM:
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR03990; EC 5.4.2.10; HMM-score: 171.6)
    and 3 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 97.5)
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 97.5)
    Metabolism Energy metabolism Sugars phosphoglucomutase, alpha-D-glucose phosphate-specific (TIGR01132; EC 5.4.2.2; HMM-score: 74.1)
  • TheSEED: see SACOL2501
  • PFAM:
    no clan defined PGM_PMM_I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PF02878; HMM-score: 142.1)
    and 4 more
    PGM_PMM_II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PF02879; HMM-score: 93.7)
    PGM_PMM_III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PF02880; HMM-score: 56.7)
    PGM_PMM_IV; Phosphoglucomutase/phosphomannomutase, C-terminal domain (PF00408; HMM-score: 32.3)
    Peptidase_MH (CL0035) Amidase_3; N-acetylmuramoyl-L-alanine amidase (PF01520; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Mg2+
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02324
    • TAT(Tat/SPI): 0.000711
    • LIPO(Sec/SPII): 0.005581
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLQSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGFEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2501
  • protein localization: see SACOL2501
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=SACOL_RS13105&oldid=90568"