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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_00907
  • pan locus tag?: SAUPAN003080000
  • symbol: SAOUHSC_00907
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_00907
  • symbol: SAOUHSC_00907
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 876898..877287
  • length: 390
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTACATTTACATATATTAAGTTGGGTATTAGCGATTATTTTATTTATCGCTACATAC
    TTAAACATTTCAAAAAATCAAGGCAGATCACCATTTTTCAAACCGTTGCACATGATTTTA
    CGCTTATTTATGCTGTTGACGTTAATTTCAGGATTTTGGATATTAATTCAGTCATTTATG
    AATGGCGGGGCAAATCATATGTTGCTTACATTGAAAATGCTGTGTGGTGTTGCAGTAGTT
    GGATTGATGGAAGTGTCGATTGCTAAAAGAAAGAGACATGAACAAAGTCACACAATGTTT
    TGGATAACAATTGCATTAATTATCATCACAATGGTATTAGGTGTCATTCTACCGTTAGGG
    CCTATATCAAAATTATTCGGTATTGGCTAA
    60
    120
    180
    240
    300
    360
    390

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_00907
  • symbol: SAOUHSC_00907
  • description: hypothetical protein
  • length: 129
  • theoretical pI: 11.3868
  • theoretical MW: 14538.9
  • GRAVY: 1.03488

Function[edit | edit source]

  • TIGRFAM:
    MSEP-CTERM protein (TIGR04286; HMM-score: 14.1)
    and 3 more
    exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (TIGR03025; HMM-score: 9.9)
    oligosaccharyl transferase, archaeosortase A system-associated (TIGR04154; EC 2.4.1.-; HMM-score: 7.6)
    XrtN system VIT domain protein (TIGR04477; HMM-score: 2.7)
  • TheSEED  :
    • Uncharacterized protein UPF0344
    Cofactors, Vitamins, Prosthetic Groups, Pigments Tetrapyrroles CPO analysis  Uncharacterized protein UPF0344
  • PFAM:
    no clan defined DUF1516; Protein of unknown function (DUF1516) (PF07457; HMM-score: 122.7)
    and 17 more
    SirB; Invasion gene expression up-regulator, SirB (PF04247; HMM-score: 23.1)
    GPCR_A (CL0192) 7TMR-DISM_7TM; 7TM diverse intracellular signalling (PF07695; HMM-score: 15)
    no clan defined DUF3681; Protein of unknown function (DUF3681) (PF12442; HMM-score: 14)
    DUF3671; Protein of unknown function (PF12420; HMM-score: 12.5)
    DUF5345; Family of unknown function (DUF5345) (PF17280; HMM-score: 11.2)
    DUF805; Protein of unknown function (DUF805) (PF05656; HMM-score: 10.7)
    DUF2304; Uncharacterized conserved protein (DUF2304) (PF10066; HMM-score: 8.7)
    PalH; PalH/RIM21 (PF08733; HMM-score: 7.7)
    DUF5467; Family of unknown function (DUF5467) (PF17555; HMM-score: 7.6)
    DUF2206; Predicted membrane protein (DUF2206) (PF09971; HMM-score: 7)
    DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 7)
    DUF5373; Family of unknown function (DUF5373) (PF17343; HMM-score: 7)
    DUF202; Domain of unknown function (DUF202) (PF02656; HMM-score: 6.9)
    Ninjurin; Ninjurin (PF04923; HMM-score: 6.8)
    DUF1345; Protein of unknown function (DUF1345) (PF07077; HMM-score: 6.4)
    DUF5090; Domain of unknown function (DUF5090) (PF17009; HMM-score: 6.2)
    DUF4131; Domain of unknown function (DUF4131) (PF13567; HMM-score: 6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006761
    • TAT(Tat/SPI): 0.000206
    • LIPO(Sec/SPII): 0.030199
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLHLHILSWVLAIILFIATYLNISKNQGRSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]