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NCBI: 03-AUG-2016
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus NCTC8325
- locus tag: SAOUHSC_02193
- pan locus tag?: SAUPAN001538000
- symbol: SAOUHSC_02193
- pan gene symbol?: —
- synonym:
- product: prohead protease
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAOUHSC_02193
- symbol: SAOUHSC_02193
- product: prohead protease
- replicon: chromosome
- strand: -
- coordinates: 2053338..2053922
- length: 585
- essential: no DEG
⊟Accession numbers[edit | edit source]
- Gene ID: 3919559 NCBI
- RefSeq: YP_500678 NCBI
- BioCyc: G1I0R-2072 BioCyc
- MicrobesOnline: 1290634 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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541ATGAGTAAGGAAACGAGAGTTGGCAACATTATTGAGGTACGCTCAAATGATAACAACGAA
ATGGTCATAGAGGGGTATGCGTTAAAGTTTGACACTTGGTCTGAAAATCTTGGTGGATTC
AAAGAAACGATTTCACGTCGCGCTTTAGAAAACACTGATTTATCTGATGTGCGTTGTTTA
GTAGATCATATCCCATCGCAAATAATTGGTAGGACAAAATCGGGTACTTTGGAGCTCGAA
ACTGATGATGTTGGACTTAAATATCGTTGTAAGTTACCAAACACAACATTTGCACGTGAT
TTATATGAGAACATGCGTGTAGGCAACATCAATCAATGTTCGTTTGGTTTTATGCTTGAC
GATAAAGGCGATGAAGTGCGTTTTGATGAACAAGAAAACATTTACAAACGTACTTTAACA
GCAATTCGTGAACTTACAGATGTTTCTGTAGTGACTTATCCGGCTTACAAAGACACTGAT
GTTAAACCAGCATTACGTAGTATTGAAACCGTTAAAAAAGAACAACGTAAAAAAGAATTA
GAAATAAGACTAAAGAAACACTCTATATTAAATAATATTTGGTGA60
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585
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAOUHSC_02193
- symbol: SAOUHSC_02193
- description: prohead protease
- length: 194
- theoretical pI: 5.91304
- theoretical MW: 22457.3
- GRAVY: -0.647938
⊟Function[edit | edit source]
- TIGRFAM: Mobile and extrachromosomal element functions Prophage functions phage prohead protease, HK97 family (TIGR01543; EC 3.4.-.-; HMM-score: 95.5)Protein fate Other phage prohead protease, HK97 family (TIGR01543; EC 3.4.-.-; HMM-score: 95.5)
- TheSEED :
- Phage head maturation protease
- PFAM: Peptidase_SH (CL0201) Peptidase_S78; Caudovirus prohead serine protease (PF04586; HMM-score: 195.9)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003964
- TAT(Tat/SPI): 0.000292
- LIPO(Sec/SPII): 0.000362
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSKETRVGNIIEVRSNDNNEMVIEGYALKFDTWSENLGGFKETISRRALENTDLSDVRCLVDHIPSQIIGRTKSGTLELETDDVGLKYRCKLPNTTFARDLYENMRVGNINQCSFGFMLDDKGDEVRFDEQENIYKRTLTAIRELTDVSVVTYPAYKDTDVKPALRSIETVKKEQRKKELEIRLKKHSILNNIW
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: [1]
Multi-gene expression profiles
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)