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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02592
  • pan locus tag?: SAUPAN005798000
  • symbol: SAOUHSC_02592
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02592
  • symbol: SAOUHSC_02592
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2383780..2383965
  • length: 186
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGACAACAGCATTAATTGGTGTAATTGTATTAATCTTACTAATTATTAGCTTTGTGCCA
    AACTACCGTGCTATGAAATCAGCAAAAGAACAAGGAAGTAATGCAACAAGAGCTACAATT
    ATGGTAGGCATAGATATTATCTTAATTGTACTTATCATCGTGACGTTATTATTAAAATAT
    ATGTAA
    60
    120
    180
    186

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_02592
  • symbol: SAOUHSC_02592
  • description: hypothetical protein
  • length: 61
  • theoretical pI: 10.3246
  • theoretical MW: 6675.29
  • GRAVY: 1.36557

Function[edit | edit source]

  • TIGRFAM:
    variant surface antigen, rifin family (TIGR01477; HMM-score: 5.9)
  • TheSEED  :
    • Hypothetical protein SAV2318
  • PFAM:
    no clan defined DUF3149; Protein of unknown function (DUF3149) (PF11346; HMM-score: 11.3)
    Omega_toxin (CL0083) Chi-conotoxin; chi-Conotoxin or t superfamily (PF16981; HMM-score: 10.3)
    no clan defined P12; Virus attachment protein p12 family (PF12669; HMM-score: 9.6)
    OppC_N; N-terminal TM domain of oligopeptide transport permease C (PF12911; HMM-score: 9.2)
    and 3 more
    Adeno_E3_CR2; Adenovirus E3 region protein CR2 (PF02439; HMM-score: 9)
    Zn_Beta_Ribbon (CL0167) DUF2116; Uncharacterized protein containing a Zn-ribbon (DUF2116) (PF09889; HMM-score: 7.3)
    VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 6.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.054124
    • TAT(Tat/SPI): 0.000861
    • LIPO(Sec/SPII): 0.059842
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTTALIGVIVLILLIISFVPNYRAMKSAKEQGSNATRATIMVGIDIILIVLIIVTLLLKYM

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]