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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002276000
- symbol?: rrlB
- synonym:
- description?: 23S ribosomal RNA
- strand?: +
- coordinates?: 2775864..2783535
- synteny block?: BlockID0015750
- occurrence?: in 56% of 34 strains
rrlB : 23S ribosomal RNA [1]
• A crystal structure is available : 6YEF
Staphylococcal 23S rRNA is modified by methylation at uridine(792) and at uridine(1966) by rlmCD, inversion of uridine(1938), uridine(1942), and uridine(1944) to pseudouridines by rluD, methylation of pseudouridine(1942) by rlmH, methylation at guanosine(2278) by rlmB, methylation at guanosine(2472) by rlmK, uridine reduction at dihydrouridine(2476), methylation at adenosine(2530) by rlmN, and methylation at guanosine(2601) by rlmQ.
⊟Orthologs[edit | edit source]
04-02981:
—
08BA02176:
C248_0586
11819-97:
MS7_0505
6850:
—
71193:
—
ECT-R 2:
ECTR2_469
ED133:
—
ED98:
—
HO 5096 0412:
SAEMRSA15_rRNA0006
JH1:
—
JH9:
SaurJH9_R0018
JKD6008:
SAA6008_r06
JKD6159:
—
LGA251:
SARLGA251_r06
M013:
—
MRSA252:
SARr006
MSHR1132:
—
MSSA476:
SASr009
Mu3:
—
Mu50:
—
MW2:
—
RF122:
—
ST398:
—
T0131:
SAT0131_r007
TCH60:
HMPREF0772_r10002
TW20:
SATW20_r060
USA300_TCH1516:
USA300HOU_r0006 (rrl2)
VC40:
—
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues:
- ↑ Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev
Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution.
FEBS Lett: 2020, 594(21);3551-3567
[PubMed:32852796] [WorldCat.org] [DOI] (I p)Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep: 2024, 14(1);14253
[PubMed:38902339] [WorldCat.org] [DOI] (I e)Roberto Bahena-Ceron, Chloé Teixeira, Jose R Jaramillo Ponce, Philippe Wolff, Florence Couzon, Pauline François, Bruno P Klaholz, François Vandenesch, Pascale Romby, Karen Moreau, Stefano Marzi
RlmQ: a newly discovered rRNA modification enzyme bridging RNA modification and virulence traits in Staphylococcus aureus.
RNA: 2024, 30(3);200-212
[PubMed:38164596] [WorldCat.org] [DOI] (I e)