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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003051000
- symbol?: mnhC1
- synonym:
- description?: Na(+)/H(+) antiporter subunit C
- Na(+)/H(+) antiporter subunit C
- monovalent cation/H+ antiporter subunit C
- putative monovalent cation/H+ antiporter subunit C
- NA+/H+ antiporter subunit C
- na(+)/H(+) antiporter subunit C (Multiple resistance and pHhomeostasis protein C) (Mrp complex subunit C)
- CPA3 family monovalent cation (K+ or Na+):proton (H+) antiporter-3 MnhC subunit
- CPA3 family monovalent cation:proton (H+) antiporter-3 subunit C
- monovalent cation antiporter-3 subunit C, MnhC
- Na(+)/H(+) antiporter subunit C1
- Na(+) H(+) antiporter subunit C
- Na+/H+ antiporter subunit
- ShaC
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 3440903..3441157
- synteny block?: BlockID0021590
- occurrence?: in 100% of 33 strains
mnhC1 (snoC): sodium/proton antiporter subunit C [1]
• previously annotated as Staphylococcal NADH:ubiquinone oxidoreductase ortholog as it could establish an ion gradient
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0905 (mnhC)
08BA02176:
C248_0949 (mnhC)
11819-97:
MS7_0905
6850:
RSAU_000827 (mnhC2)
71193:
ST398NM01_0933
ECT-R 2:
ECTR2_806
ED133:
SAOV_0896c
ED98:
SAAV_0911 (mnhC)
HO 5096 0412:
SAEMRSA15_07800 (mnhC)
JH1:
SaurJH1_0969
JH9:
SaurJH9_0950
JKD6008:
SAA6008_00903 (mnhC)
JKD6159:
SAA6159_00809 (mnhC)
LGA251:
SARLGA251_08680 (MnhC1)
M013:
M013TW_0869
MRSA252:
SAR0912 (mnhC)
MSHR1132:
SAMSHR1132_08020
MSSA476:
SAS0820
Mu3:
SAHV_0945 (mnhC)
Mu50:
SAV0950 (mnhC)
MW2:
MW0832 (mnhC)
RF122:
SAB0817c (mnhC)
ST398:
SAPIG0933
T0131:
SAT0131_00982
TCH60:
HMPREF0772_12297 (mnhC)
TW20:
SATW20_09500 (MnhC1)
USA300_TCH1516:
USA300HOU_0910 (mnhC2)
VC40:
SAVC_03925
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL -------------------MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANL
N315 -------------------MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANL
NCTC8325 -----------------------MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANL
Newman MCSSWYCHDNYYFDWRERIVEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANL
USA300_FPR3757 -----------------------MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANL
*************************************
COL FLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTD
N315 FLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTD
NCTC8325 FLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTD
Newman FLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTD
USA300_FPR3757 FLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTD
************************************************************
COL NVESMKGVPEDD
N315 NVESMKGVPEDD
NCTC8325 NVESMKGVPEDD
Newman NVESMKGVPEDD
USA300_FPR3757 NVESMKGVPEDD
************
- ↑ Manisha Vaish, Alexa Price-Whelan, Tamara Reyes-Robles, Jun Liu, Amyeo Jereen, Stephanie Christie, Francis Alonzo, Meredith A Benson, Victor J Torres, Terry A Krulwich
Roles of Staphylococcus aureus Mnh1 and Mnh2 Antiporters in Salt Tolerance, Alkali Tolerance, and Pathogenesis.
J Bacteriol: 2018, 200(5);
[PubMed:29263099] [WorldCat.org] [DOI] (I e)Masahiro Ito, Masato Morino, Terry A Krulwich
Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea.
Front Microbiol: 2017, 8;2325
[PubMed:29218041] [WorldCat.org] [DOI] (P e)