PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003116000
• symbol^?: —
• synonym:
• description^?: 2-isopropylmalate synthase

  descriptions from strain specific annotations:

  • 2-isopropylmalate synthase
  • isopropylmalate synthase-like protein
  • 2-isopropylmalate synthase, putative
  • LeuA family protein
  • HMGL-like family protein
  • isopropylmalate synthase-related protein
  • pseudogene
• strand^?: +
• coordinates^?: 3501937..3503083
• synteny block^?: BlockID0022090
• occurrence^?: in 79% of 33 strains

⊟Orthologs

COL:
SACOL0981
N315:
SA0837
NCTC8325:
SAOUHSC_00914
Newman:
NWMN_0847
USA300_FPR3757:
SAUSA300_0879
04-02981:
SA2981_0932
08BA02176:
—
11819-97:
MS7_0932
6850:
RSAU_000853
71193:
—
ECT-R 2:
ECTR2_832
ED133:
SAOV_0923
ED98:
SAAV_0937
HO 5096 0412:
SAEMRSA15_08060
JH1:
SaurJH1_0995
JH9:
SaurJH9_0976
JKD6008:
SAA6008_00929 (leuA1)
JKD6159:
—
LGA251:
SARLGA251_08940
M013:
—
MRSA252:
SAR0940
MSHR1132:
—
MSSA476:
SAS0847
Mu3:
SAHV_0972
Mu50:
SAV0977
MW2:
MW0859
RF122:
—
ST398:
—
T0131:
SAT0131_01010 (atpD)
TCH60:
HMPREF0772_12268 (leuA2)
TW20:
SATW20_09760
USA300_TCH1516:
USA300HOU_0935 (leuA1)
VC40:
SAVC_04055

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
  N315            MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
  NCTC8325        MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
  Newman          MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
  USA300_FPR3757  MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDI
                  ************************************************************
  
  COL             ISPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
  N315            LSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
  NCTC8325        LSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
  Newman          LSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
  USA300_FPR3757  LSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDC
                  :***********************************************************
  
  COL             LDILKKDKKGVDICFEDGTRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
  N315            LDILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
  NCTC8325        LDILKKDKKGVDICFEDGTRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
  Newman          LDILKKDKKGVDICFEDGTRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
  USA300_FPR3757  LDILKKDKKGVDICFEDGTRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFN
                  *****************.******************************************
  
  COL             YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITIL
  N315            YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITIL
  NCTC8325        YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITIL
  Newman          YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITIL
  USA300_FPR3757  YFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLRIGERAGNAPIEEIITIL
                  ****************************************** *****************
  
  COL             TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
  N315            TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
  NCTC8325        TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
  Newman          TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
  USA300_FPR3757  TKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMY
                  ************************************************************
  
  COL             QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
  N315            QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
  NCTC8325        QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
  Newman          QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
  USA300_FPR3757  QYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVA
                  ************************************************************
  
  COL             PEDTVDLLQIIKRRSKDGNFK
  N315            PEDTVDLLQIIKRRSKDGNFK
  NCTC8325        PEDTVDLLQIIKRRSKDGNFK
  Newman          PEDTVDLLQIIKRRSKDGNFK
  USA300_FPR3757  PEDTVDLLQIIKRRSKDGNFK
                  *********************