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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003266000
- symbol?: fmtA
- synonym:
- description?: protein FmtA
- protein FmtA
- fmt protein
- autolysis and methicillin resistance-related protein FmtA
- autolysis and methicillin resistant-related protein FmtA
- FmtA, autolysis and methicillin resistant-related protein
- methicillin resistance protein FmtA
- teichoic acid D-Ala esterase FmtA
- Autolysis and methicillin resistant-related protein
- affects cell wall cross-linking and amidation
- beta-lactamase
- beta-lactamase family protein
- carboxypeptidase
- FmtA protein involved in methicillin resistance
- S12 family carboxypeptidase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3642915..3644108
- synteny block?: BlockID0023500
- occurrence?: in 100% of 33 strains
fmtA : teichoic acid D-amino acid esterase FmtA [1]
• A crystal structure is available : 5ZH8
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1011 (fmtA)
08BA02176:
C248_1082 (fmt)
11819-97:
MS7_1014 (fmtA)
6850:
RSAU_000944 (fmtA)
71193:
ST398NM01_1054
ECT-R 2:
ECTR2_912
ED133:
SAOV_1003
ED98:
SAAV_1021
HO 5096 0412:
SAEMRSA15_08880 (fmt)
JH1:
SaurJH1_1139
JH9:
SaurJH9_1116
JKD6008:
SAA6008_01012
JKD6159:
SAA6159_00913
LGA251:
SARLGA251_09710 (fmt)
M013:
M013TW_0988
MRSA252:
SAR1030 (fmt)
MSHR1132:
SAMSHR1132_09050
MSSA476:
SAS0992
Mu3:
SAHV_1049 (fmt)
Mu50:
SAV1057 (fmt)
MW2:
MW0940 (fmt)
RF122:
SAB0923 (fmt)
ST398:
SAPIG1054
T0131:
SAT0131_01092
TCH60:
HMPREF0772_12177 (fmt2)
TW20:
SATW20_10530 (fmt)
USA300_TCH1516:
USA300HOU_1001 (fmt1)
VC40:
SAVC_04450
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKV
N315 MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKV
NCTC8325 MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKV
Newman MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKV
USA300_FPR3757 MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKV
************************************************************
COL APSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPN
N315 APSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPN
NCTC8325 APSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPN
Newman APSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPN
USA300_FPR3757 APSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPN
************************************************************
COL TMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKY
N315 TMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKY
NCTC8325 TMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKY
Newman TMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKY
USA300_FPR3757 TMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKY
************************************************************
COL KSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIG
N315 KSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIG
NCTC8325 KSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIG
Newman KSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIG
USA300_FPR3757 KSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIG
************************************************************
COL DPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLIT
N315 DPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLIT
NCTC8325 DPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLIT
Newman DPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLIT
USA300_FPR3757 DPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLIT
************************************************************
COL QIQQYKLFSPKITNPLLHEFGTKKYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYV
N315 QIQQYKLFSPKITNPLLHEFGTKQYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYV
NCTC8325 QIQQYKLFSPKITNPLLHEFGTKKYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYV
Newman QIQQYKLFSPKITNPLLHEFGTKKYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYV
USA300_FPR3757 QIQQYKLFSPKITNPLLHEFGTKKYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYV
***********************:************************************
COL VVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
N315 VVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
NCTC8325 VVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
Newman VVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
USA300_FPR3757 VVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
*************************************
- ↑ Muhammad M Rahman, Howard N Hunter, Shamina Prova, Vidhu Verma, Aneela Qamar, Dasantila Golemi-Kotra
The Staphylococcus aureus Methicillin Resistance Factor FmtA Is a d-Amino Esterase That Acts on Teichoic Acids.
mBio: 2016, 7(1);e02070-15
[PubMed:26861022] [WorldCat.org] [DOI] (I e)