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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003849000
- symbol?: ctpA
- synonym:
- description?: serine protease
- serine protease
- carboxyl-terminal protease
- carboxy-terminal processing proteinase ctpA
- putative carboxy-terminal processing proteinase
- S41 family peptidase
- carboxy-processing protease
- carboxy-terminal processing protease
- C-terminal processing peptidase family protein
- ctpA-like serine protease
- putative carboxy-terminal processing proteinasectpA
- putative CtpA-like serine protease
- putative protease
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4134288..4135783
- synteny block?: BlockID0029050
- occurrence?: in 100% of 33 strains
ctpA: carboxyl-terminus processing protease[1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1374 (ctpA)
08BA02176:
C248_1460
11819-97:
MS7_1376
6850:
RSAU_001299 (ctpA)
71193:
ST398NM01_1421
ECT-R 2:
ECTR2_1276
ED133:
SAOV_1429c
ED98:
SAAV_1403
HO 5096 0412:
SAEMRSA15_12830
JH1:
SaurJH1_1509
JH9:
SaurJH9_1480
JKD6008:
SAA6008_01388
JKD6159:
SAA6159_01287
LGA251:
SARLGA251_13360
M013:
M013TW_1366
MRSA252:
SAR1432
MSHR1132:
SAMSHR1132_12620
MSSA476:
SAS1363
Mu3:
SAHV_1408 (ctpA)
Mu50:
SAV1420 (ctpA)
MW2:
MW1310 (ctpA)
RF122:
SAB1275c
ST398:
SAPIG1421
T0131:
SAT0131_01500
TCH60:
HMPREF0772_11787
TW20:
SATW20_14210
USA300_TCH1516:
USA300HOU_1357 (ctpA)
VC40:
SAVC_06350
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
N315 MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIF
NCTC8325 MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
Newman MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
USA300_FPR3757 MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
********************************************** *************
COL INQKISGLNKTDQSNLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
N315 INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
NCTC8325 INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
Newman INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
USA300_FPR3757 INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
*************:**********************************************
COL KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
N315 KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
NCTC8325 KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
Newman KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
USA300_FPR3757 KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
************************************************************
COL GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
N315 GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
NCTC8325 GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
Newman GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
USA300_FPR3757 GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
********************************************:***************
COL QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
N315 QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
NCTC8325 QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
Newman QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
USA300_FPR3757 QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
************************************************************
COL TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
N315 TEAIQTSNDSLKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
NCTC8325 TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
Newman TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
USA300_FPR3757 TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
*********:**************************************************
COL REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
N315 REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
NCTC8325 REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
Newman REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
USA300_FPR3757 REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
************************************************************
COL IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
N315 IKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
NCTC8325 IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
Newman IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
USA300_FPR3757 IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
***********************:************************************
COL ANKHDDVLDKLINILK
N315 ANKHDDVLDKLINILK
NCTC8325 ANKHDDVLDKLINILK
Newman ANKHDDVLDKLINILK
USA300_FPR3757 ANKHDDVLDKLINILK
****************
- ↑ Ronan K Carroll, Frances E Rivera, Courtney K Cavaco, Grant M Johnson, David Martin, Lindsey N Shaw
The lone S41 family C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and contributes to virulence.
Microbiology (Reading): 2014, 160(Pt 8);1737-1748
[PubMed:24928312] [WorldCat.org] [DOI] (I p)Martin S Bojer, Katarzyna Wacnik, Peter Kjelgaard, Clement Gallay, Amy L Bottomley, Marianne T Cohn, Gunnar Lindahl, Dorte Frees, Jan-Willem Veening, Simon J Foster, Hanne Ingmer
SosA inhibits cell division in Staphylococcus aureus in response to DNA damage.
Mol Microbiol: 2019, 112(4);1116-1130
[PubMed:31290194] [WorldCat.org] [DOI] (I p)