PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN004072000
• symbol^?: bfmBAA
• synonym:
• description^?: 2-oxoisovalerate dehydrogenase subunit alpha

  descriptions from strain specific annotations:

  • 2-oxoisovalerate dehydrogenase subunit alpha
  • 2-oxoisovalerate dehydrogenase, E1 component, alpha subunit
  • 2-oxoisovalerate dehydrogenase, E1 component subunit alpha
  • branched-chain alpha-keto acid dehydrogenase E1
  • thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
  • Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit
  • 2-oxoisovalerate dehydrogenase alpha subunit
  • 2-oxoisovalerate dehydrogenase E1 subunit alpha
  • 2-oxoisovalerate dehydrogenase subunit alpha (branched-chain alpha-keto acid dehydrogenase e1 component alpha chain) (bckdhe1-alpha)
  • 3-methyl-2-oxobutanoate dehydrogenase
  • pyruvate dehydrogenase (acetyl-transferring) alpha subunit
• strand^?: -
• coordinates^?: 4353434..4354433
• synteny block^?: BlockID0031040
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1562
N315:
SA1348 (bfmBAA)
NCTC8325:
SAOUHSC_01613
Newman:
NWMN_1423
USA300_FPR3757:
SAUSA300_1466
04-02981:
SA2981_1476 (bfmBAA)
08BA02176:
C248_1560 (bfmBAA)
11819-97:
MS7_1535 (bfmBAA)
6850:
RSAU_001384
71193:
ST398NM01_1583
ECT-R 2:
ECTR2_1369
ED133:
SAOV_1518
ED98:
SAAV_1510
HO 5096 0412:
SAEMRSA15_14380 (bfmBAA)
JH1:
SaurJH1_1609
JH9:
SaurJH9_1576
JKD6008:
SAA6008_01487 (acoA)
JKD6159:
SAA6159_01453 (acoA)
LGA251:
SARLGA251_14240 (bfmBAA)
M013:
M013TW_1533
MRSA252:
SAR1595 (bfmBAA)
MSHR1132:
SAMSHR1132_13580
MSSA476:
SAS1456
Mu3:
SAHV_1505 (bfmBAA)
Mu50:
SAV1517 (bfmBAA)
MW2:
MW1470 (bfmBAA)
RF122:
SAB1390c
ST398:
SAPIG1583
T0131:
SAT0131_01611
TCH60:
HMPREF0772_11623 (bkdA)
TW20:
SATW20_15140 (bfmBAA)
USA300_TCH1516:
USA300HOU_1519 (odpA)
VC40:
SAVC_06835

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVVSGQGQEATQIGMAYAL
  N315            MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVVSGQGQEATQIGMAYAL
  NCTC8325        MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVVSGQGQEATQIGMAYAL
  Newman          MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVVSGQGQEATQIGMAYAL
  USA300_FPR3757  MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVVSGQGQEATQIGMAYAL
                  ************************************************************
  
  COL             EEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGKQMPSHFSSRAKNILSQSS
  N315            EEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGKQMPSHFSSRAKNILSQSS
  NCTC8325        EEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGKQMPSHFSSRAKNILSQSS
  Newman          EEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGKQMPSHFSSRAKNILSQSS
  USA300_FPR3757  EEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGKQMPSHFSSRAKNILSQSS
                  ************************************************************
  
  COL             PVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFHEGLNFAGVHKLPFVCVIINN
  N315            PVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFHEGLNFAGVHKLPFVCVIINN
  NCTC8325        PVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFHEGLNFAGVHKLPFVCVIINN
  Newman          PVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFHEGLNFAGVHKLPFVCVIINN
  USA300_FPR3757  PVATQIPHAVGAALALKMDGKKKIATATVGEGSSNQGDFHEGLNFAGVHKLPFVCVIINN
                  ************************************************************
  
  COL             KYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLAMYKAMKEARDRAISGQGSTLIE
  N315            KYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLAMYKAMKEARDRAISGQGSTLIE
  NCTC8325        KYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLAMYKAMKEARDRAISGQGSTLIE
  Newman          KYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLAMYKAMKEARDRAISGQGSTLIE
  USA300_FPR3757  KYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLAMYKAMKEARDRAISGQGSTLIE
                  ************************************************************
  
  COL             AVTSRMTAHSSDDDDQYRTKEERETLKKADCNEKFKKELLSAGIIDDAWLAEIEAEHKDI
  N315            AVTSRMTAHSSDDDDQYRTKEEREALKKADCNEKFKKELLSAGIIDDAWLAEIEAEHKDI
  NCTC8325        AVTSRMTAHSSDDDDQYRTKEERETLKKADCNEKFKKELLSAGIIDDAWLAEIEAEHKDI
  Newman          AVTSRMTAHSSDDDDQYRTKEERETLKKADCNEKFKKELLSAGIIDDAWLAEIEAEHKDI
  USA300_FPR3757  AVTSRMTAHSSDDDDQYRTKEERETLKKADCNEKFKKELLSAGIIDDAWLAEIEAEHKDI
                  ************************:***********************************
  
  COL             INKATKAAEDAPYPSVEEAYAFVYEEGSLN
  N315            INKATKAAEDAPYPSVEEAYAFVYEEGSLN
  NCTC8325        INKATKAAEDAPYPSVEEAYAFVYEEGSLN
  Newman          INKATKAAEDAPYPSVEEAYAFVYEEGSLN
  USA300_FPR3757  INKATKAAEDAPYPSVEEAYAFVYEEGSLN
                  ******************************