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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004553000
- symbol?: —
- synonym:
- description?: ATP-binding protein
- ATP-binding protein
- NTPase
- pseudogene
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4771706..4777825
- synteny block?: BlockID0035430
- occurrence?: in 30% of 33 strains
Suggest a pan gene symbol of "avs2" and a description of "AVAST bacteriophage defense system type II" to harmonize with PMID 36302390 with further validation information at DefenseFinder. AVAST systems are STAND (signal transduction ATPase with numerous domains) NTPases that recognize phage large subunit terminase proteins (C-terminal domain) and trigger abortive infection via the N-terminal effector domain (i.e. nuclease, protease, etc) per PMID 35951700.
⊟Orthologs[edit | edit source]
04-02981:
—
08BA02176:
—
11819-97:
—
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
—
HO 5096 0412:
—
JH1:
—
JH9:
—
JKD6008:
—
JKD6159:
—
LGA251:
—
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
SAS1729
Mu3:
—
Mu50:
—
MW2:
MW1749
RF122:
—
ST398:
—
T0131:
SAT0131_01926
TCH60:
—
TW20:
SATW20_18000
USA300_TCH1516:
USA300HOU_1798
VC40:
SAVC_08265
⊟Genome Viewer[edit | edit source]
| COL | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL ------------------------------------------------------------
NCTC8325 MKRSTNQEKFLDTLIRLNTKIEELGKINILNNHIYSEYFFRDLLNIVYGYSLENHNKKQK
Newman ------------------------------------------------------------
USA300_FPR3757 MKRSTNQEKFLDTLIRLNTKIEELGKINILNNHIYSEYFFRDLLNIVYGYSLENHNKKQK
COL ---------------------------------------MEEGYRLKFIFIGNQNNNIKN
NCTC8325 NAPAFDLIDNTNKIIIQVTATCKKQKIEDTLKKEYLTNKMEEGYRLKFIFIGNQNNNIKN
Newman ---------------------------------------MEEGYRLKFIFIGNQNNNIKN
USA300_FPR3757 NAPAFDLIDNTNKIIIQVTATCKKQKIEDTLKKEYLTNKMEEGYRLKFIFIGNQNNNIKN
*********************
COL KNFSNPHNILFDSKKDIILTQDLCEEFLNLNINKQDHAIELLKKELSPLLFEDSLSYLKE
NCTC8325 KNFSNPHNILFDSKKDIILTQDLCEEFLNLNINKQDHAIELLKKELSPLLFEDSLSYLKE
Newman KNFSNPHNILFDSKKDIILTQDLCEEFLNLNINKQDHAIELLKKELSPLLFEDSLSYLKE
USA300_FPR3757 KNFSNPHNILFDSKKDIILTQDLCEEFLNLNINKQDHAIELLKKELSPLLFEDSLSYLKE
************************************************************
COL EFINEKLEFNISNLASRYTANNDVDTINNKIIEGISITNNFKYTNISYLKELKGYIENDI
NCTC8325 EFINEKLEFNISNLASRYTANNDVDTINNKIIEGISITNNFKYTNISYLKELKGYIENDI
Newman EFINEKLEFNISNLASRYTANNDVDTINNKIIEGISITNNFKYTNISYLKELKGYIENDI
USA300_FPR3757 EFINEKLEFNISNLASRYTANNDVDTINNKIIEGISITNNFKYTNISYLKELKGYIENDI
************************************************************
COL LDKMKSKYAKNIYLNFKKIFSNLEQSVNNYLELEEEFEEKKKYLSEIYELIDEINIDPYI
NCTC8325 LDKMKSKYAKNIYLNFKKIFSNLEQSVNNYLELEEEFEEKKKYLSEIYELIDEINIDPYI
Newman LDKMKSKYAKNIYLNFKKIFSNLEQSVNNYLELEEEFEEKKKYLSEIYELIDEINIDPYI
USA300_FPR3757 LDKMKSKYAKNIYLNFKKIFSNLEQSVNNYLELEEEFEEKKKYLSEIYELIDEINIDPYI
************************************************************
COL FLTEHNECNIYKISENEKLELQTYMSKIEKVLLKYQTYLKETCKECLFYPYLLVQGEAGI
NCTC8325 FLTEHNECNIYKISENEKLELQTYMSKIEKVLLKYQTYLKETCKECLFYPYLLVQGEAGI
Newman FLTEHNECNIYKISENEKLELQTYMSKIEKVLLKYQTYLKETCKECLFYPYLLVQGEAGI
USA300_FPR3757 FLTEHNECNIYKISENEKLELQTYMSKIEKVLLKYQTYLKETCKECLFYPYLLVQGEAGI
************************************************************
COL GKSHLLAHLSKKLRDENHIIYLFLGQFFTKNEDPWHQILNDLEVTNSVDNFLRSISNKAK
NCTC8325 GKSHLLAHLSKKLRDENHIIYLFLGQFFTKNEDPWHQILNDLEVTNSVDNFLRSISNKAK
Newman GKSHLLAHLSKKLRDENHIIYLFLGQFFTKNEDPWHQILNDLEVTNSVDNFLRSISNKAK
USA300_FPR3757 GKSHLLAHLSKKLRDENHIIYLFLGQFFTKNEDPWHQILNDLEVTNSVDNFLRSISNKAK
************************************************************
COL ETKKRAFIIIDALNEGEGKRLWGNYFQSFINHIKKYSNIALIFSIRTPFEDVILPKNAIQ
NCTC8325 ETKKRAFIIIDALNEGEGKRLWGNYFQSFINHIKKYSNIALIFSIRTPFEDVILPKNAIQ
Newman ETKKRAFIIIDALNEGEGKRLWGNYFQSFINHIKKYSNIALIFSIRTPFEDVILPKNAIQ
USA300_FPR3757 ETKKRAFIIIDALNEGEGKRLWGNYFQSFINHIKKYSNIALIFSIRTPFEDVILPKNAIQ
************************************************************
COL DNNIVVFQHEGFSKEENYNPIVSFCDFYGLELPKLPILNPEFNNPLFLKLMCEYCVNKFK
NCTC8325 DNNIVVFQHEGFSKEENYNPIVSFCDFYGLELPKLPILNPEFNNPLFLKLMCEYCVNKFK
Newman DNNIVVFQHEGFSKEENYNPIVSFCDFYGLELPKLPILNPEFNNPLFLKLMCEYCVNKFK
USA300_FPR3757 DNNIVVFQHEGFSKEENYNPIVSFCDFYGLELPKLPILNPEFNNPLFLKLMCEYCVNKFK
************************************************************
COL EFDQTISVAELFTNVLKTVNINLSKEDKFDFDKNINVVQKVIKGLVELMNDSEFNQLNYE
NCTC8325 EFDQTISVAELFTNVLKTVNINLSKEDKFDFDKNINVVQKVIKGLVELMNDSEFNQLNYE
Newman EFDQTISVAELFTNVLKTVNINLSKEDKFDFDKNINVVQKVIKGLVELMNDSEFNQLNYE
USA300_FPR3757 EFDQTISVAELFTNVLKTVNINLSKEDKFDFDKNINVVQKVIKGLVELMNDSEFNQLNYE
************************************************************
COL ESYTVVNNIAKEYVQKSNRFLEALIDENILIKNTGYKGEMIIYFSYERMGDYFLSEYLLE
NCTC8325 ESYTVVNNIAKEYVQKSNRFLEALIDENILIKNTGYKGEMIIYFSYERMGDYFLSEYLLE
Newman ESYTVVNNIAKEYVQKSNRFLEALIDENILIKNTGYKGEMIIYFSYERMGDYFLSEYLLE
USA300_FPR3757 ESYTVVNNIAKEYVQKSNRFLEALIDENILIKNTGYKGEMIIYFSYERMGDYFLSEYLLE
************************************************************
COL KYRNVDKRDLVTKLQSDEKVTRYFQKEDDLSYNRGLINELFIKLANEFNIELFEVFPQFK
NCTC8325 KYRNVDKRDLVTKLQSDEKVTRYFQKEDDLSYNRGLINELFIKLANEFNIELFEVFPQFK
Newman KYRNVDKRDLVTKLQSDEKVTRYFQKEDDLSYNRGLINELFIKLANEFNIELFEVFPQFK
USA300_FPR3757 KYRNVDKRDLVTKLQSDEKVTRYFQKEDDLSYNRGLINELFIKLANEFNIELFEVFPQFK
************************************************************
COL NNYNMIYSFINSLVWRKDGSISKHTKCYISDNVIPYDAFRNNFLDVLLIKMPQKNHPLNI
NCTC8325 NNYNMIYSFINSLVWRKDGSISKHTKCYISDNVIPYDAFRNNFLDVLLIKMPQKNHPLNI
Newman NNYNMIYSFINSLVWRKDGSISKHTKCYISDNVIPYDAFRNNFLDVLLIKMPQKNHPLNI
USA300_FPR3757 NNYNMIYSFINSLVWRKDGSISKHTKCYISDNVIPYDAFRNNFLDVLLIKMPQKNHPLNI
************************************************************
COL WALHKLLKQCNLGKRDFLWTQYISINNEKVFEIINWLFSNYKKLDEETAEKYMIFLTWIF
NCTC8325 WALHKLLKQCNLGKRDFLWTQYISINNEKVFEIINWLFSNYKKLDEETAEKYMIFLTWIF
Newman WALHKLLKQCNLGKRDFLWTQYISINNEKVFEIINWLFSNYKKLDEETAEKYMIFLTWIF
USA300_FPR3757 WALHKLLKQCNLGKRDFLWTQYISINNEKVFEIINWLFSNYKKLDEETAEKYMIFLTWIF
************************************************************
COL SATNNKLRDLGTKSLVKLFKTFPTKIIGLLKLFENNNDPYIVERLYASVLGATLRIDICE
NCTC8325 SATNNKLRDLGTKSLVKLFKTFPTKIIGLLKLFENNNDPYIVERLYASVLGATLRIDICE
Newman SATNNKLRDLGTKSLVKLFKTFPTKIIGLLKLFENNNDPYIVERLYASVLGATLRIDICE
USA300_FPR3757 SATNNKLRDLGTKSLVKLFKTFPTKIIGLLKLFENNNDPYIVERLYASVLGATLRIDICE
************************************************************
COL IHIEIANYIYEEIFDKEMVYPHILMRDYARQTIEYISLSKDISNINLEKIRPPYKSNWYK
NCTC8325 IHIEIANYIYEEIFDKEMVYPHILMRDYARQTIEYISLSKDISNINLEKIRPPYKSNWYK
Newman IHIEIANYIYEEIFDKEMVYPHILMRDYARQTIEYISLSKDISNINLEKIRPPYKSNWYK
USA300_FPR3757 IHIEIANYIYEEIFDKEMVYPHILMRDYARQTIEYISLSKDISNINLEKIRPPYKSNWYK
************************************************************
COL KEYSNLNIDDYIKSLKNKLDSHLHFSIDKIKNSMTTEYGRGTGAYGDFGRYVFGYAVRNW
NCTC8325 KEYSNLNIDDYIKSLKNKLDSHLHFSIDKIKNSMTTEYGRGTGAYGDFGRYVFGYAVRNW
Newman KEYSNLNIDDYIKSLKNKLDSHLHFSIDKIKNSMTTEYGRGTGAYGDFGRYVFGYAVRNW
USA300_FPR3757 KEYSNLNIDDYIKSLKNKLDSHLHFSIDKIKNSMTTEYGRGTGAYGDFGRYVFGYAVRNW
************************************************************
COL VKGFKSDQDLSNIALMRIFEMGYDAKLHGEFDMWVNRYDNFNNSIERISKKYQWIAYYEI
NCTC8325 VKGFKSDQDLSNIALMRIFEMGYDAKLHGEFDMWVNRYDNFNNSIERISKKYQWIAYYEI
Newman VKGFKSDQDLSNIALMRIFEMGYDAKLHGEFDMWVNRYDNFNNSIERISKKYQWIAYYEI
USA300_FPR3757 VKGFKSDQDLSNIALMRIFEMGYDAKLHGEFDMWVNRYDNFNNSIERISKKYQWIAYYEI
************************************************************
COL LAKLVDKFPDVQYSGLWDDYIRDIDPTLLLLEIDK-------------------------
NCTC8325 LAKLVDKFPDVQYSGLWDDYIRDIDPTLLLLEIDKESKILVPSPLPSHQSNEWVKNTKVF
Newman LAKLVDKFPDVQYSGLWDDYIRDIDPTLLLLEIDK-------------------------
USA300_FPR3757 LAKLVDKFPDVQYSGLWDDYIRDIDPTLLLLEIDKESKILVPSPLPSHQSNEWVKNTKVF
***********************************
COL ------------------------------------------------------------
NCTC8325 DETKLFLEIDIDNHRYICLSSKFNFEKREKEIPFEDRDSCYFLAMGYFYNKEDSNEIIKG
Newman ------------------------------------------------------------
USA300_FPR3757 DETKLFLEIDIDNHRYICLSSKFNFEKREKEIPFEDRDSCYFLAMGYFYNKEDSNEIIKG
COL ------------------------------------------------------------
NCTC8325 YENNYDRGINIPRAHSIYLYEYYWSEAYKNYKEGYLTESDGKLCPAIYEYFWELDYSVKD
Newman ------------------------------------------------------------
USA300_FPR3757 YENNYDRGINIPRAHSIYLYEYYWSEAYKNYKEGYLTESDGKLCPAIYEYFWELDYSVKD
COL ------------------------------------------------------------
NCTC8325 KSISFYIPCKEIVDYFSLIQTEEGVWKTKFGETICINSKLLEFDNECLLIKKESLLNFLN
Newman ------------------------------------------------------------
USA300_FPR3757 KSISFYIPCKEIVDYFSLIQTEEGVWKTKFGETICINSKLLEFDNECLLIKKESLLNFLN
COL --------------------------------------------------
NCTC8325 TKKLSIGWKIYLEKISLRDRQEWWYNVFYDDGKYNKKIIKNDMSKIRRNF
Newman --------------------------------------------------
USA300_FPR3757 TKKLSIGWKIYLEKISLRDRQEWWYNVFYDDGKYNKKIIKNDMSKIRRNF