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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004782000
- symbol?: airS
- synonym:
- description?: sensor histidine kinase
- sensor histidine kinase
- GAF domain-containing sensor histidine kinase
- putative sensor histidine kinase
- two-component sensor histidine kinase
- GAF sensor signal transduction histidine kinase
- histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein
- histidine kinase dimerisation and phosphoacceptor region
- histidine kinase protein
- Nitrate/nitrite sensor protein
- putative histidine kinase
- sensor histidine kinase, putative
- two-component response regulator sensor protein, histidine kinase
- two-component response system sensor histidine kinase
- two-component sensor histidine kinase-like protein
- Two-component sensor protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4991719..4992831
- synteny block?: BlockID0037140
- occurrence?: in 100% of 33 strains
airS (yhcS): anaerobic iron-sulfur redox sensor histidine kinase [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1805
08BA02176:
C248_1892
11819-97:
MS7_1854
6850:
RSAU_001708
71193:
ST398NM01_1915
ECT-R 2:
ECTR2_1691
ED133:
SAOV_1846
ED98:
SAAV_1868
HO 5096 0412:
SAEMRSA15_17540
JH1:
SaurJH1_1937
JH9:
SaurJH9_1903
JKD6008:
SAA6008_01806 (yhcS)
JKD6159:
SAA6159_01777 (yhcS)
LGA251:
SARLGA251_17320 (yhcS)
M013:
M013TW_1855
MRSA252:
SAR1940
MSHR1132:
SAMSHR1132_16950
MSSA476:
SAS1770
Mu3:
SAHV_1834 (yhcS)
Mu50:
SAV1849
MW2:
MW1790
RF122:
SAB1782c
ST398:
SAPIG1915
T0131:
SAT0131_01969
TCH60:
HMPREF0772_11295
TW20:
SATW20_18430 (yhcS)
USA300_TCH1516:
USA300HOU_1843
VC40:
SAVC_08485
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHV
N315 MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHV
NCTC8325 MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHV
Newman MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHV
USA300_FPR3757 MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHV
************************************************************
COL ALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHA
N315 ALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHA
NCTC8325 ALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHA
Newman ALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHA
USA300_FPR3757 ALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHA
************************************************************
COL TVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINE
N315 TVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINE
NCTC8325 TVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINE
Newman TVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINE
USA300_FPR3757 TVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINE
************************************************************
COL RNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQL
N315 RNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEKTSQNAVNEMRALIWQL
NCTC8325 RNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQL
Newman RNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQL
USA300_FPR3757 RNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQL
*******************************************:****************
COL KPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTN
N315 KPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTN
NCTC8325 KPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTN
Newman KPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTN
USA300_FPR3757 KPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTN
************************************************************
COL KMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKG
N315 KMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKG
NCTC8325 KMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKG
Newman KMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKG
USA300_FPR3757 KMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKG
************************************************************
COL TQIQFTIPIK
N315 TQIQFTIPIK
NCTC8325 TQIQFTIPIK
Newman TQIQFTIPIK
USA300_FPR3757 TQIQFTIPIK
**********
- ↑ Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)Fei Sun, Quanjiang Ji, Marcus B Jones, Xin Deng, Haihua Liang, Bryan Frank, Joshua Telser, Scott N Peterson, Taeok Bae, Chuan He
AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.
J Am Chem Soc: 2012, 134(1);305-14
[PubMed:22122613] [WorldCat.org] [DOI] (I p)Haipeng Sun, Yifan Yang, Ting Xue, Baolin Sun
Modulation of cell wall synthesis and susceptibility to vancomycin by the two-component system AirSR in Staphylococcus aureus NCTC8325.
BMC Microbiol: 2013, 13;286
[PubMed:24320748] [WorldCat.org] [DOI] (I e)Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji
The AirSR two-component system contributes to Staphylococcus aureus survival in human blood and transcriptionally regulates sspABC operon.
Front Microbiol: 2015, 6;682
[PubMed:26191060] [WorldCat.org] [DOI] (P e)Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji
The Staphylococcus aureus AirSR Two-Component System Mediates Reactive Oxygen Species Resistance via Transcriptional Regulation of Staphyloxanthin Production.
Infect Immun: 2017, 85(2);
[PubMed:27872240] [WorldCat.org] [DOI] (I e)