⊟Summary[edit | edit source]

pan ID^?: SAUPAN005352000
symbol^?: kdpE
synonym:
description^?: DNA-binding response regulator
- DNA-binding response regulator
- response regulator transcription factor
- DNA-binding response regulator, KdpE
- DNA-binding response regulator KdpE
- KDP operon transcriptional regulatory protein
- KDP operon transcriptional regulatory protein KdpE
- two-component response regulator KdpE
- KdpE protein
- KDP operon response regulator KdpE
- response regulator protein
- response regulator receiver
- response regulator receiver domain/transcriptional regulatory protein
- two component sensor protein
- Two component transcriptional regulator, winged helix family
- winged helix family two component transcriptional regulator
strand^?: +
coordinates^?: 5527473..5528162
synteny block^?: BlockID0041490
occurrence^?: in 100% of 34 strains

kdpE : potassium-responsive response regulator ^[1]

⊟Orthologs[edit | edit source]

COL:

SACOL2071 (kdpE)

N315:

SA1883 (kdpE)

NCTC8325:

SAOUHSC_02315

Newman:

NWMN_1984 (kdpE)

USA300_FPR3757:

SAUSA300_2036 (kdpE)

JSNZ:

JSNZ_002041

04-02981:

SA2981_2020 (kdpE)

08BA02176:

C248_2091 (kdpE)

11819-97:

MS7_2096

6850:

RSAU_001919 (kdpE)

71193:

ST398NM01_2121

ECT-R 2:

ECTR2_1935

ED133:

SAOV_2121

ED98:

SAAV_2134 (kdpE)

HO 5096 0412:

SAEMRSA15_19890 (kdpE)

JH1:

SaurJH1_2154

JH9:

SaurJH9_2116

JKD6008:

SAA6008_02118 (kdpE)

JKD6159:

SAA6159_01994 (kdpE)

LGA251:

SARLGA251_18820 (kdpE)

M013:

M013TW_2038

MRSA252:

SAR2167 (kdpE)

MSHR1132:

SAMSHR1132_19040

MSSA476:

SAS1984

Mu3:

SAHV_2064 (kdpE)

Mu50:

SAV2079 (kdpE)

MW2:

MW2003 (kdpE)

RF122:

SAB1964 (kdpE)

ST398:

SAPIG2121

T0131:

SAT0131_02238

TCH60:

HMPREF0772_11115 (kdpE)

TW20:

SATW20_22190 (kdpE)

USA300_TCH1516:

USA300HOU_2075 (kdpE)

VC40:

SAVC_09280

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

alignment of orthologues:
CLUSTAL format alignment by MAFFT L-INS-i (v7.505)

COL             MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
N315            MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
NCTC8325        MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
Newman          MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
USA300_FPR3757  MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
JSNZ            MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
                ************************************************************

COL             GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
N315            GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
NCTC8325        GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
Newman          GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
USA300_FPR3757  GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
JSNZ            GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
                ************************************************************

COL             KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
N315            KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
NCTC8325        KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
Newman          KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
USA300_FPR3757  KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
JSNZ            KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
                ************************************************************

COL             IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
N315            IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
NCTC8325        IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
Newman          IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
USA300_FPR3757  IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
JSNZ            IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
                ***************************************************

↑ Liping Zhao, Ting Xue, Fei Shang, Haipeng Sun, Baolin Sun
Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence.
Infect Immun: 2010, 78(8);3506-15
[PubMed:20498265] [WorldCat.org] [DOI] (I p)Ting Xue, Yibo You, De Hong, Haipeng Sun, Baolin Sun
The Staphylococcus aureus KdpDE two-component system couples extracellular K+ sensing and Agr signaling to infection programming.
Infect Immun: 2011, 79(6);2154-67
[PubMed:21422185] [WorldCat.org] [DOI] (I p)Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)

[1] Liping Zhao, Ting Xue, Fei Shang, Haipeng Sun, Baolin Sun
Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence.
Infect Immun: 2010, 78(8);3506-15
[PubMed:20498265] [WorldCat.org] [DOI] (I p)Ting Xue, Yibo You, De Hong, Haipeng Sun, Baolin Sun
The Staphylococcus aureus KdpDE two-component system couples extracellular K+ sensing and Agr signaling to infection programming.
Infect Immun: 2011, 79(6);2154-67
[PubMed:21422185] [WorldCat.org] [DOI] (I p)Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)

[1]

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Contents

⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757
JSNZ

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⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]