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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005557000
- symbol?: sdrM
- synonym:
- description?: MFS transporter
- MFS transporter
- drug transporter
- major facilitator superfamily drug transporter, putative
- putative drug transporter
- drug resistance-involved transporter
- drug transporter, putative
- Major facilitator superfamily MFS_1
- major facilitator superfamily protein
- major facilitator superfamily transporter
- major facilitator transporter
- MFS family major facilitator transporter
- Multidrug resistance protein B
- Permease
- putative transport protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5699917..5701260
- synteny block?: BlockID0043180
- occurrence?: in 94% of 33 strains
sdrM: staphylococcus drug resistance multidrug transporter [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2107
08BA02176:
C248_2205
11819-97:
MS7_2192
6850:
RSAU_002013
71193:
ST398NM01_2229
ECT-R 2:
ECTR2_2030
ED133:
SAOV_2216c
ED98:
SAAV_2230
HO 5096 0412:
SAEMRSA15_20740
JH1:
SaurJH1_2238
JH9:
SaurJH9_2200
JKD6008:
SAA6008_02207
JKD6159:
SAA6159_02080
LGA251:
SARLGA251_19640
M013:
M013TW_2135
MRSA252:
SAR2260
MSHR1132:
SAMSHR1132_20010
MSSA476:
SAS2070
Mu3:
—
Mu50:
—
MW2:
MW2095
RF122:
SAB2050c
ST398:
SAPIG2229
T0131:
SAT0131_02337
TCH60:
HMPREF0772_11023
TW20:
SATW20_23040
USA300_TCH1516:
USA300HOU_2160
VC40:
SAVC_09715
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
N315 MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
NCTC8325 MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
Newman MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
USA300_FPR3757 MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
************************************************************
COL VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
N315 VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
NCTC8325 VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
Newman VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
USA300_FPR3757 VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
************************************************************
COL LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
N315 LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
NCTC8325 LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
Newman LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
USA300_FPR3757 LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
************************************************************
COL FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
N315 FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
NCTC8325 FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
Newman FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
USA300_FPR3757 FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
************************************************************
COL KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
N315 KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
NCTC8325 KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
Newman KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
USA300_FPR3757 KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
************************************************************
COL SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
N315 SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
NCTC8325 SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
Newman SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
USA300_FPR3757 SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
************************************************************
COL YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
N315 YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
NCTC8325 YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
Newman YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
USA300_FPR3757 YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
************************************************************
COL SAVAVISIGLIVLWVVFFKEQSSQSKE
N315 SAVAVISIGLIVLWVVFFKEQSSQSKE
NCTC8325 SAVAVISIGLIVLWVVFFKEQSSQSKE
Newman SAVAVISIGLIVLWVVFFKEQSSQSKE
USA300_FPR3757 SAVAVISIGLIVLWVVFFKEQSSQSKE
***************************
- ↑ Youichi Yamada, Koh-ichiro Hideka, Sumiko Shiota, Teruo Kuroda, Tomofusa Tsuchiya
Gene cloning and characterization of SdrM, a chromosomally-encoded multidrug efflux pump, from Staphylococcus aureus.
Biol Pharm Bull: 2006, 29(3);554-6
[PubMed:16508166] [WorldCat.org] [DOI] (P p)