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⊟Summary[edit | edit source]
- pan ID?: SAUPAN006209000
- symbol?: —
- synonym:
- description?: methylated-DNA--[protein]-cysteine S-methyltransferase
- methylated-DNA--[protein]-cysteine S-methyltransferase
- methylated-DNA--protein-cysteine methyltransferase
- methylated DNA-protein cysteine methyltransferase AdaB
- putative 6-O-methylguanine DNAmethyltransferase
- 6-O-methylguanine DNA methyltransferase
- methylated-DNA-[]-cysteine S-methyltransferase family protein
- methylated-DNA-[protein]-cysteine S-methyltransferase family protein
- methylated-DNA-protein-cysteine S-methyltransferase
- O6-methylguanine-DNA methyltransferase
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 6269246..6269767
- synteny block?: BlockID0049330
- occurrence?: in 100% of 33 strains
adaB (ogt): methylated-DNA:protein-cysteine methyltransferase[1]
catalyzes transfer of inappropriately O-methylated guanine (OGT) or O-methylated thymidine (OTT) directly to AdaB enzyme, permanently deactivating the enzyme.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2483 (adaB)
08BA02176:
C248_2604
11819-97:
MS7_2553
6850:
RSAU_002388
71193:
ST398NM01_2597
ECT-R 2:
ECTR2_2399
ED133:
SAOV_2591c
ED98:
SAAV_2613 (ogt)
HO 5096 0412:
SAEMRSA15_24500
JH1:
SaurJH1_2623
JH9:
SaurJH9_2570
JKD6008:
SAA6008_02585 (ada)
JKD6159:
SAA6159_02443 (ada)
LGA251:
SARLGA251_23220
M013:
M013TW_2520
MRSA252:
SAR2627
MSHR1132:
SAMSHR1132_23670
MSSA476:
SAS2433
Mu3:
SAHV_2531 (adaB)
Mu50:
SAV2547 (adaB)
MW2:
MW2468 (adaB)
RF122:
SAB2422c (adaB)
ST398:
SAPIG2597 (ogt)
T0131:
SAT0131_02756 (miaA)
TCH60:
HMPREF0772_10644 (ogt)
TW20:
SATW20_26690
USA300_TCH1516:
USA300HOU_2541 (ogt)
VC40:
SAVC_11615
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MEYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGTREENTSLAIFREATQWLDAYFKGD
N315 MEYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGTREENTSLAIFREATQWLDAYFKGD
NCTC8325 MEYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGTREENTSLAIFREATQWLDAYFKGD
Newman MEYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGTREENTSLAIFREATQWLDAYFKGD
USA300_FPR3757 MEYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGTREENTSLAIFREATQWLDAYFKGD
************************************************************
COL NPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVGKLLNKPKMSAQAVGGAVG
N315 NPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVGKVLDKPKMSAQAVGGAVG
NCTC8325 NPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVGKLLNKPKMSAQAVGGAVG
Newman NPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVGKLLNKPKMSAQAVGGAVG
USA300_FPR3757 NPEITIPLKPTGSHFQQCVWNELRQVPYGTLTTYGAIAKKVGKLLNKPKMSAQAVGGAVG
*******************************************:*:**************
COL SNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENIDMSKLYVPKHSTKP
N315 SNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENIDMSKLYIPKHSTKP
NCTC8325 SNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENIDMSKLYVPKHSTKP
Newman SNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENIDMSKLYVPKHSTKP
USA300_FPR3757 SNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENIDMSKLYVPKHSTKP
*********************************************:*******
- ↑ Kam Pou Ha, Andrew M Edwards
DNA Repair in Staphylococcus aureus.
Microbiol Mol Biol Rev: 2021, 85(4);e0009121
[PubMed:34523959] [WorldCat.org] [DOI] (I p)