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⊟Summary[edit | edit source]
- pan ID?: SAUPAN006337000
- symbol?: nsaS
- synonym: braS
- description?: sensor histidine kinase
- sensor histidine kinase
- nisin susceptibility-associated sensor histidine kinase
- nisin susceptibility-associated two-component system sensor histidine kinase NsaS
- susceptibility-associated sensor histidine kinase
- two-component sensor histidine kinase, putative
- Putative two-component sensor histidine kinase
- sensor kinase
- two-component sensor histidine kinase
- ATPase
- histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein
- integral membrane sensor signal transduction histidine kinase
- sensor histidine kinase, putative
- sensor kinase protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 6378307..6379194
- synteny block?: BlockID0050530
- occurrence?: in 100% of 34 strains
nsaS : nisin susceptibility-associated sensor histidine kinase [1]
• alternate accepted nomenclature is braS : bacitractin resistance-associated sensor histidine kinase
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2563
08BA02176:
C248_2691
11819-97:
MS7_2629
6850:
RSAU_002467
71193:
ST398NM01_2673
ECT-R 2:
ECTR2_2478
ED133:
SAOV_2672c
ED98:
SAAV_2692
HO 5096 0412:
SAEMRSA15_25280
JH1:
SaurJH1_2703
JH9:
SaurJH9_2647
JKD6008:
SAA6008_02683
JKD6159:
SAA6159_02520
JSNZ:
JSNZ_002612 (nsaS)
LGA251:
SARLGA251_23960
M013:
M013TW_2603
MRSA252:
SAR2702
MSHR1132:
SAMSHR1132_24400
MSSA476:
SAS2510
Mu3:
SAHV_2608
Mu50:
SAV2624
MW2:
MW2544
RF122:
SAB2499c
ST398:
SAPIG2673
T0131:
SAT0131_02887
TCH60:
HMPREF0772_10565
TW20:
SATW20_27620
USA300_TCH1516:
USA300HOU_2623 (nsaS)
VC40:
SAVC_11990
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKT
N315 MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKT
NCTC8325 MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKT
Newman MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKT
USA300_FPR3757 MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKT
************************************************************
COL ISQQQQIENLENALYQLKNEQIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNR
N315 ISQQQQIENLETALYQLKNEQIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNR
NCTC8325 ISQQQQIENLENALYQLKNEQIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNR
Newman ISQQQQIENLENALYQLKNEQIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNR
USA300_FPR3757 ISQQQQIENLENALYQLKNEQIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNR
***********.************************************************
COL VRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIRPIIMKYSIQFIDQKTKIHYE
N315 VRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIRPIIMKYSIQFIDQKTKIHYE
NCTC8325 VRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIRPIIMKYSIQFIDQKTKIHYE
Newman VRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIRPIIMKYSIQFIDQKTKIHYE
USA300_FPR3757 VRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIRPIIMKYSIQFIDQKTKIHYE
************************************************************
COL PCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
N315 PCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
NCTC8325 PCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
Newman PCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
USA300_FPR3757 PCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
************************************************************
COL IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
N315 IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
NCTC8325 IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
Newman IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
USA300_FPR3757 IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE
*******************************************************
- ↑ Aurélia Hiron, Mélanie Falord, Jaione Valle, Michel Débarbouillé, Tarek Msadek
Bacitracin and nisin resistance in Staphylococcus aureus: a novel pathway involving the BraS/BraR two-component system (SA2417/SA2418) and both the BraD/BraE and VraD/VraE ABC transporters.
Mol Microbiol: 2011, 81(3);602-22
[PubMed:21696458] [WorldCat.org] [DOI] (I p)Christopher P Randall, Arya Gupta, Bret Utley-Drew, Siu Yi Lee, Genevieve Morrison-Williams, Alex J O'Neill
Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module.
mSphere: 2018, 3(6);
[PubMed:30541781] [WorldCat.org] [DOI] (I e)Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)