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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_0037 [new locus tag: SAUSA300_RS00200 ]
  • pan locus tag?: SAUPAN000444000
  • symbol: ccrB
  • pan gene symbol?: ccrB
  • synonym:
  • product: cassette chromosome recombinase B

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_0037 [new locus tag: SAUSA300_RS00200 ]
  • symbol: ccrB
  • product: cassette chromosome recombinase B
  • replicon: chromosome
  • strand: -
  • coordinates: 45892..47520
  • length: 1629
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAA
    AGCACAGAAGGTTATAGTATCGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTC
    CATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTATTTCAGGTAAATCTATGAAC
    AGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
    GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGAT
    TTACACAAACAAAATGTCGAATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCT
    TCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAGAATTCGAACGTAATAACATT
    GTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
    TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACAT
    GAAGCTAATATTGTAAAATATATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAA
    ATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAAAGGGGAAACCTTTCAGTATT
    AGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
    TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAA
    GGTAAGCATTCCCCCATTATTAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAA
    CAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGAATCTGCTTACAGGCATTATT
    CACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
    GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAA
    GTATGTTCGGCAAACAGTGTAAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATA
    CTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAGTAACACACGTCAATCAAGAA
    AATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
    GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACA
    TCAGTAATCAGACCAAGTATTCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAA
    ATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTTTATTTGATGCCAAAGAAATC
    AGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
    GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAA
    CAATTCTATGTCACACTCAAACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAA
    CAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTTTGCCCCAAACACTATATCTT
    ACTATTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1629

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_0037 [new locus tag: SAUSA300_RS00200 ]
  • symbol: CcrB
  • description: cassette chromosome recombinase B
  • length: 542
  • theoretical pI: 9.79919
  • theoretical MW: 62654.4
  • GRAVY: -0.628044

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Cassette chromosome recombinase B
  • PFAM:
    no clan defined Resolvase; Resolvase, N terminal domain (PF00239; HMM-score: 141.9)
    and 12 more
    Recombinase; Recombinase (PF07508; HMM-score: 90)
    Zn_Beta_Ribbon (CL0167) Ogr_Delta; Ogr/Delta-like zinc finger (PF04606; HMM-score: 65.4)
    Zn_ribbon_recom; Recombinase zinc beta ribbon domain (PF13408; HMM-score: 56.6)
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger (PF01396; HMM-score: 15.1)
    no clan defined Laminin_II; Laminin Domain II (PF06009; HMM-score: 15.1)
    TMPIT; TMPIT-like protein (PF07851; HMM-score: 15)
    HTH (CL0123) HTH_21; HTH-like domain (PF13276; HMM-score: 14.7)
    no clan defined DUF1796; Putative papain-like cysteine peptidase (DUF1796) (PF08795; HMM-score: 12.2)
    Zn_Beta_Ribbon (CL0167) zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 11.8)
    no clan defined Tho2; Transcription factor/nuclear export subunit protein 2 (PF11262; HMM-score: 9.9)
    DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 7.2)
    FlxA; FlxA-like protein (PF14282; HMM-score: 6.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018476
    • TAT(Tat/SPI): 0.00105
    • LIPO(Sec/SPII): 0.003324
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVMVYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGNLPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAKYKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKDGTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYDEVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLKALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]