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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_0699 [new locus tag: SAUSA300_RS03750 ]
- pan locus tag?: SAUPAN002600000
- symbol: SAUSA300_0699
- pan gene symbol?: pabB
- synonym:
- product: chorismate-binding domain-containing protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_0699 [new locus tag: SAUSA300_RS03750 ]
- symbol: SAUSA300_0699
- product: chorismate-binding domain-containing protein
- replicon: chromosome
- strand: +
- coordinates: 772854..774005
- length: 1152
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3913213 NCBI
- RefSeq: YP_493402 NCBI
- BioCyc: see SAUSA300_RS03750
- MicrobesOnline: 1292214 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1141GTGAGAATAGAATATAATTATCGCTACTATTTAACTGAAAATGAATATAAGCAATACCAT
ATTCAATTAAAGGGATTTATAAAGAAGTATGTTGCTACTAAGTTGGCTGATGTGGGAGAA
GTGATACACTTTGCACAAGCGCAGCAACGACAAGGTAGATATGTCTCGTTATATTTAAGT
TACGAAGCGGCAAAGTATTTTAATCATGCTATGTGTACACATTCATTAGCTAAAGATGAT
ATTTATGCAGCAGCTTATAGTTTTGAAAAAGCGGAAAGCATAAATTCAACATATGAACAT
CAAACTTCTTATGTATCAAAGTATCATTTTTCATTTGTTGAATCTTCTGAGGTTATGATG
ACTAATATTAAACGTGTCCAACAAGCAATTGTTGAAGGCGAAACGTATCAAGTGAACTAT
ACGGCGCGCTTAACGGATAACATTTATTATCCTATTAGTACTTTATATGAACGATTAACT
CAATTTAGTAATGGTAATTATACTGCGTTATTACAAACTGATGAAATCCAAGTAGCGTCT
ATCTCACCAGAATTATTTTTTCAAAAAGGACAATTTAACAATGTCGATAACGTTATCATA
AGCAAACCGATGAAAGGGACAATGCCTAGAGGTAAAACGGAAGCTGAAGATCAACAGTAT
TATAAAACATTGCAAACTTCTTCGAAAGATCGTGCAGAAAATGTCATGATTGTTGATTTA
CTAAGAAACGATATAGGGAGAATATCACAGAGTGGCTCAATTAAGGTGTATAAACTATTT
TTTATTGAGGCATATAAAACTGTATTTCAAATGACTTCGATGGTAAGTGGAACTTTAAAA
AATAATACAGACTTAACTCAAATTTTAACATCGTTATTTCCTTGTGGTTCGATTACAGGT
GCACCGAAACTGAATACAATGAAATATATTAAACAATTAGAAAGTTCACCTCGTGGTATA
TACTGCGGAGCAATTGGACTATTACTTCCAACTGAAGATGATAAAATGATTTTTAATATT
CCGATTCGCACTATTGAGTATAAATATGGACAAGCGATTTATGGAGTCGGAGCAGGTATT
ACAATTGATTCTAAGCCAAAAGATGAAGTGAATGAATTTTACGCAAAAACCAAGATTTTG
GAGATGTTATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_0699 [new locus tag: SAUSA300_RS03750 ]
- symbol: SAUSA300_0699
- description: chorismate-binding domain-containing protein
- length: 383
- theoretical pI: 8.30263
- theoretical MW: 43964.8
- GRAVY: -0.358225
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate synthase, component I (TIGR00553; EC 2.6.1.85; HMM-score: 328.3)aminodeoxychorismate synthase, component I (TIGR01824; EC 2.6.1.85; HMM-score: 270.6)and 8 moreAmino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR00564; EC 4.1.3.27; HMM-score: 223.7)Amino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR01820; EC 4.1.3.27; HMM-score: 207.7)aminodeoxychorismate synthase (TIGR01823; EC 2.6.1.85; HMM-score: 140.4)Amino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR00565; EC 4.1.3.27; HMM-score: 128.6)Amino acid biosynthesis Aromatic amino acid family anthranilate synthase (TIGR01815; EC 4.1.3.27; HMM-score: 105.5)salicylate synthase (TIGR03494; EC 4.1.3.-,5.4.4.2; HMM-score: 96.3)Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone isochorismate synthase (TIGR00543; EC 5.4.4.2; HMM-score: 93)Arabidopsis thaliana cystatin-related protein (TIGR01638; HMM-score: 13)
- TheSEED :
- Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)
Amino Acids and Derivatives Aromatic amino acids and derivatives Tryptophan synthesis Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)and 1 more - PFAM: no clan defined Chorismate_bind; chorismate binding enzyme (PF00425; HMM-score: 270.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008779
- TAT(Tat/SPI): 0.00043
- LIPO(Sec/SPII): 0.000798
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHAMCTHSLAKDDIYAAAYSFEKAESINSTYEHQTSYVSKYHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKNNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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