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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS03750 [old locus tag: SAUSA300_0699 ]
  • pan locus tag?: SAUPAN002600000
  • symbol: SAUSA300_RS03750
  • pan gene symbol?: pabB
  • synonym:
  • product: para-aminobenzoate synthetase subunit I

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS03750 [old locus tag: SAUSA300_0699 ]
  • symbol: SAUSA300_RS03750
  • product: para-aminobenzoate synthetase subunit I
  • replicon: chromosome
  • strand: +
  • coordinates: 772854..774005
  • length: 1152
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    GTGAGAATAGAATATAATTATCGCTACTATTTAACTGAAAATGAATATAAGCAATACCAT
    ATTCAATTAAAGGGATTTATAAAGAAGTATGTTGCTACTAAGTTGGCTGATGTGGGAGAA
    GTGATACACTTTGCACAAGCGCAGCAACGACAAGGTAGATATGTCTCGTTATATTTAAGT
    TACGAAGCGGCAAAGTATTTTAATCATGCTATGTGTACACATTCATTAGCTAAAGATGAT
    ATTTATGCAGCAGCTTATAGTTTTGAAAAAGCGGAAAGCATAAATTCAACATATGAACAT
    CAAACTTCTTATGTATCAAAGTATCATTTTTCATTTGTTGAATCTTCTGAGGTTATGATG
    ACTAATATTAAACGTGTCCAACAAGCAATTGTTGAAGGCGAAACGTATCAAGTGAACTAT
    ACGGCGCGCTTAACGGATAACATTTATTATCCTATTAGTACTTTATATGAACGATTAACT
    CAATTTAGTAATGGTAATTATACTGCGTTATTACAAACTGATGAAATCCAAGTAGCGTCT
    ATCTCACCAGAATTATTTTTTCAAAAAGGACAATTTAACAATGTCGATAACGTTATCATA
    AGCAAACCGATGAAAGGGACAATGCCTAGAGGTAAAACGGAAGCTGAAGATCAACAGTAT
    TATAAAACATTGCAAACTTCTTCGAAAGATCGTGCAGAAAATGTCATGATTGTTGATTTA
    CTAAGAAACGATATAGGGAGAATATCACAGAGTGGCTCAATTAAGGTGTATAAACTATTT
    TTTATTGAGGCATATAAAACTGTATTTCAAATGACTTCGATGGTAAGTGGAACTTTAAAA
    AATAATACAGACTTAACTCAAATTTTAACATCGTTATTTCCTTGTGGTTCGATTACAGGT
    GCACCGAAACTGAATACAATGAAATATATTAAACAATTAGAAAGTTCACCTCGTGGTATA
    TACTGCGGAGCAATTGGACTATTACTTCCAACTGAAGATGATAAAATGATTTTTAATATT
    CCGATTCGCACTATTGAGTATAAATATGGACAAGCGATTTATGGAGTCGGAGCAGGTATT
    ACAATTGATTCTAAGCCAAAAGATGAAGTGAATGAATTTTACGCAAAAACCAAGATTTTG
    GAGATGTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1152

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS03750 [old locus tag: SAUSA300_0699 ]
  • symbol: SAUSA300_RS03750
  • description: para-aminobenzoate synthetase subunit I
  • length: 383
  • theoretical pI: 8.30263
  • theoretical MW: 43964.8
  • GRAVY: -0.358225

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate synthase, component I (TIGR00553; EC 2.6.1.85; HMM-score: 328.3)
    aminodeoxychorismate synthase, component I (TIGR01824; EC 2.6.1.85; HMM-score: 270.6)
    and 8 more
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR00564; EC 4.1.3.27; HMM-score: 223.7)
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR01820; EC 4.1.3.27; HMM-score: 207.7)
    aminodeoxychorismate synthase (TIGR01823; EC 2.6.1.85; HMM-score: 140.4)
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase component I (TIGR00565; EC 4.1.3.27; HMM-score: 128.6)
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase (TIGR01815; EC 4.1.3.27; HMM-score: 105.5)
    salicylate synthase (TIGR03494; EC 4.1.3.-,5.4.4.2; HMM-score: 96.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone isochorismate synthase (TIGR00543; EC 5.4.4.2; HMM-score: 93)
    Arabidopsis thaliana cystatin-related protein (TIGR01638; HMM-score: 13)
  • TheSEED: see SAUSA300_0699
  • PFAM:
    no clan defined Chorismate_bind; chorismate binding enzyme (PF00425; HMM-score: 270.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008779
    • TAT(Tat/SPI): 0.00043
    • LIPO(Sec/SPII): 0.000798
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHAMCTHSLAKDDIYAAAYSFEKAESINSTYEHQTSYVSKYHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKNNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]