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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2133 [new locus tag: SAUSA300_RS11745 ]
  • pan locus tag?: SAUPAN005564000
  • symbol: SAUSA300_2133
  • pan gene symbol?:
  • synonym:
  • product: transporter gate domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2133 [new locus tag: SAUSA300_RS11745 ]
  • symbol: SAUSA300_2133
  • product: transporter gate domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2306116..2307432
  • length: 1317
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCTTTAATTGGTATCTTATTATTTTTAGTACCAATTCCAGTCGAACAAGATGGACAG
    AAGCAAACAACGTTGCCCGTGGCATTTTTAGCAGGCGTGCTTAAAGATGTATTAGGTGGC
    GTAATGCCATTTTTAATTGTGACGATAATTACTTTATCGGGTATCATAACTCTGATTTGT
    TCAACTATTTTAAAAGATAAATTGAAACCTGACGGGCTAATGAACAATGCTTTTAACGTT
    AGAATTGGTTGGTTAATTTTACGAATATTAGCAGTTGTTTTTGCATGGATGACATTTTTA
    CGAATTGGTTCAAAGGTTATTTACTCAGATGAAACGGGTGGATTATTGTTCTCAAGTTTA
    TTGCCAACATTAGTGGCAGTATTCTTATTTGCAGCTCTATTTTTACCGCTATTAATGGAA
    TACGGTTTGTTAGAGATGTTGGGTCCTATTTTTAGACCGGTTATGAGACCTTTATTTACA
    TTGCCAGGACGTTCGACGGTAGATAATTTAGCATCATTTATTGGAGACGGAACTGTTGGT
    GTCTTAATTACAAGTAGACAATATGGTGAAGGATATTATTCTCGTCGTGAGGCAACAGTT
    ATTTCAACGACATTTAGTGTAGTTTCTATCACCTTTGCAATTGTAGTTGCTGAAACAGTG
    CACATGCAAAATCAATTTTTTGCTTTCTATTTATCAGTGATAGTATCCTGCCTCGTTGCA
    GCAGTCATTATGCCAAGAATTTGGCCTTTAAATAAAATTCCTGATGAGTATGCTAAGGAG
    GTACCTGAAAGTGCGCGTACTGAGGCATTGCCAGAAGGAAAGACGGCATTGAGACATGGC
    TTTGATACTGCAACAGAAGTAGGTATTAAAGCACCGGGCGTTATTGACTTTTTTAAGTCA
    GGATTAAAAACAGTCATTGATATGTGGTTTGTTATTTTGCCTGTAGTAATGAGTATTGGT
    ACTATTGCTACCATTATTGCGAACTACACGCCCTTTTTTGTCATATTGGGTAAACCTTTT
    GTTCCATTTTTAGAGTTAATGCAAATACCTGAAGCGGCACAGGCTTCTCAAACGATTATT
    ATCGGTTTTGCCGATATGTTTTTACCTTCTATATTAATTGAAGGTGTACAAAATGATATA
    ACTCGTTTTGTTATTGGGGCACTTAGTATATCGCAGTTAATATACTTGTCTGAAGTAGGT
    GGCGTCATACTTGGTTCGAAGATTCCTGTAAGCATCGGCAAATTGTTTATGATTTTCTTG
    ATTAGAACAATCATTACACTACCAATTATTTCTTTGATGGCACATCTTTTGTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1317

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_2133 [new locus tag: SAUSA300_RS11745 ]
  • symbol: SAUSA300_2133
  • description: transporter gate domain-containing protein
  • length: 438
  • theoretical pI: 6.79531
  • theoretical MW: 47883.1
  • GRAVY: 0.890183

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination sporulation integral membrane protein YlbJ (TIGR02871; HMM-score: 14.9)
  • TheSEED  :
    • Uncharacterized protein SAV2174
    Amino Acids and Derivatives Arginine; urea cycle, polyamines Arginine Biosynthesis extended  Predicted arginine uptake transporter
  • PFAM:
    no clan defined Gate; Nucleoside recognition (PF07670; HMM-score: 31.7)
    and 1 more
    T_cell_tran_alt; T-cell leukemia translocation-altered (PF15128; HMM-score: 16.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.034157
    • TAT(Tat/SPI): 0.000275
    • LIPO(Sec/SPII): 0.018432
  • predicted transmembrane helices (TMHMM): 9

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSLIGILLFLVPIPVEQDGQKQTTLPVAFLAGVLKDVLGGVMPFLIVTIITLSGIITLICSTILKDKLKPDGLMNNAFNVRIGWLILRILAVVFAWMTFLRIGSKVIYSDETGGLLFSSLLPTLVAVFLFAALFLPLLMEYGLLEMLGPIFRPVMRPLFTLPGRSTVDNLASFIGDGTVGVLITSRQYGEGYYSRREATVISTTFSVVSITFAIVVAETVHMQNQFFAFYLSVIVSCLVAAVIMPRIWPLNKIPDEYAKEVPESARTEALPEGKTALRHGFDTATEVGIKAPGVIDFFKSGLKTVIDMWFVILPVVMSIGTIATIIANYTPFFVILGKPFVPFLELMQIPEAAQASQTIIIGFADMFLPSILIEGVQNDITRFVIGALSISQLIYLSEVGGVILGSKIPVSIGKLFMIFLIRTIITLPIISLMAHLLL

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]